SLC4A4

GENE INFORMATION

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Gene name

SLC4A4 (HGNC Symbol)

Synonyms

hhNMC, HNBC1, NBC1, NBC2, pNBC, SLC4A5

Description

Solute carrier family 4 (sodium bicarbonate cotransporter), member 4 (HGNC Symbol)

Entrez gene summary

This gene encodes a sodium bicarbonate cotransporter (NBC) involved in the regulation of bicarbonate secretion and absorption and intracellular pH. Mutations in this gene are associated with proximal renal tubular acidosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]

Chromosome

4

Cytoband

q13.3

Chromosome location (bp)

71187286 - 71572087

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000080493 (version 78.38)

Entrez gene

8671

UniProt

Q9Y6R1 (UniProt - Evidence at protein level)

neXtProt

NX_Q9Y6R1

Antibodypedia

SLC4A4 antibodies
 

PROTEIN VIEW

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SLC4A4-001
 
SLC4A4-002
 
SLC4A4-003
 
SLC4A4-004
 
SLC4A4-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SLC4A4-001 ENSP00000344272
ENST00000340595
Q9Y6R1
Show all »
Show » Show » 1035 116 No >9
SLC4A4-002 ENSP00000264485
ENST00000264485
Q9Y6R1
Show all »
Show » Show » 1079 121.5 No >9
SLC4A4-003 ENSP00000307349
ENST00000351898
Q9Y6R1
Show all »
Show » Show » 995 112.3 No 9
SLC4A4-004 ENSP00000422400
ENST00000512686
Q9Y6R1
Show all »
Show » Show » 646 72 No 4
SLC4A4-201 ENSP00000393557
ENST00000425175
Q9Y6R1
Show all »
Show » Show » 1094 123.2 No >9