FGF4

GENE INFORMATION

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Gene name

FGF4 (HGNC Symbol)

Synonyms

HBGF-4, HST, HST-1, HSTF1, K-FGF, KFGF

Description

Fibroblast growth factor 4 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene was identified by its oncogenic transforming activity. This gene and FGF3, another oncogenic growth factor, are located closely on chromosome 11. Co-amplification of both genes was found in various kinds of human tumors. Studies on the mouse homolog suggested a function in bone morphogenesis and limb development through the sonic hedgehog (SHH) signaling pathway. [provided by RefSeq, Jul 2008]

Chromosome

11

Cytoband

q13.3

Chromosome location (bp)

69771016 - 69775403

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000075388 (version 78.38)

Entrez gene

2249

UniProt

P08620 (UniProt - Evidence at protein level)

neXtProt

NX_P08620

Antibodypedia

FGF4 antibodies
 

PROTEIN VIEW

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FGF4-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

FGF4-001 ENSP00000168712
ENST00000168712
P08620
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