TRPC5

GENE INFORMATION

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Gene name

TRPC5 (HGNC Symbol)

Synonyms

PPP1R159

Description

Transient receptor potential cation channel, subfamily C, member 5 (HGNC Symbol)

Entrez gene summary

This gene belongs to the transient receptor family. It encodes one of the seven mammalian TRPC (transient receptor potential channel) proteins. The encoded protein is a multi-pass membrane protein and is thought to form a receptor-activated non-selective calcium permeant cation channel. The protein is active alone or as a heteromultimeric assembly with TRPC1, TRPC3, and TRPC4. It also interacts with multiple proteins including calmodulin, CABP1, enkurin, Na(+)-H+ exchange regulatory factor (NHERF ), interferon-induced GTP-binding protein (MX1), ring finger protein 24 (RNF24), and SEC14 domain and spectrin repeat-containing protein 1 (SESTD1). [provided by RefSeq, May 2010]

Chromosome

X

Cytoband

q23

Chromosome location (bp)

111774315 - 112082776

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000072315 (version 78.38)

Entrez gene

7224

UniProt

Q9UL62 (UniProt - Evidence at protein level)

neXtProt

NX_Q9UL62

Antibodypedia

TRPC5 antibodies
 

PROTEIN VIEW

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TRPC5-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

TRPC5-001 ENSP00000262839
ENST00000262839
Q9UL62
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