Tissue expression of BID - Summary - The Human Protein Atlas

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BID

TISSUE

SUBCELL

CELL LINE

CANCER

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN ANTIBODY/ANTIGEN


Dictionary

GENERAL INFORMATION ? »
Protein class Protein class the gene product belongs to according to selected gene lists. List of protein classes. Predicted localization Protein localization predicted from several bioinformatic algorithms. More info... Number of transcripts Number of protein-coding transcribed from this gene as defined by Ensembl.
Gene name	BID
Gene description	BH3 interacting domain death agonist
Protein class	Mitochondrial proteins Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	11
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:	Expressed in all
GTEx:	Expressed in all

Protein evidence

Evidence at protein level

Protein localization

Cytoplasmic expression in lymphocytes and urothelial cells.

ANTIBODY RELIABILITY ? »
Data reliability description Standardized explanatory sentences with additional information required for full understanding of the knowledge-based expression profile. Currently, not all genes have been analyzed by knowledge-based annotation, indicated by "Pending RNA-based expert annotation", when applicable. Data reliability Data reliability score (score description), divided into supportive (premium) or uncertain (not premium), is based on consistency between the staining pattern of one antibody or several antibodies with RNA-seq data and available gene/protein characterization data.
Data reliability description	Pending RNA-based expert annotation.
Data reliability	Supportive based on 2 antibodies. HPA000722 , CAB003771
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM)

Protein expression (score)

Brain

Cerebral cortex

Hippocampus

N/A

Lateral ventricle

N/A

Cerebellum

N/A

Endocrine tissues

Thyroid gland

Parathyroid gland

N/A

Adrenal gland

Bone marrow & immune system

Appendix

Bone marrow

Lymph node

Tonsil

Spleen

Muscle tissues

Heart muscle

Skeletal muscle

Smooth muscle

Lung

Nasopharynx

N/A

Bronchus

N/A

Lung

Liver & gallbladder

Liver

Gallbladder

Pancreas

Gastrointestinal tract

Oral mucosa

N/A

Salivary gland

Esophagus

Stomach

Duodenum

Small intestine

Colon

Rectum

Kidney & urinary bladder

Kidney

Urinary bladder

Male tissues

Testis

Epididymis

N/A

Prostate

Seminal vesicle

N/A

Female tissues

Breast

N/A

Vagina

N/A

Cervix, uterine

N/A

Endometrium

Fallopian tube

Ovary

Placenta

Adipose & soft tissue

Adipose tissue

Soft tissue

N/A

Skin

PROTEIN EXPRESSION OVERVIEW

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Organ

Expression

RNA EXPRESSION OVERVIEW

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HPA dataset

RNA tissue category:

Expressed in all

Organ

Expression

GTEx dataset

RNA tissue category:

Expressed in all

Organ

Expression

GENE INFORMATION ? »
Gene information from Ensembl and Entrez, as well as links to available gene identifiers are displayed here. Information was retrieved from Ensembl if not indicated otherwise.
Gene name	BID
Synonyms
Description	BH3 interacting domain death agonist (HGNC Symbol)
Entrez gene summary	This gene encodes a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2. The encoded protein is a member of the BCL-2 family of cell death regulators. It is a mediator of mitochondrial damage induced by caspase-8 (CASP8); CASP8 cleaves this encoded protein, and the COOH-terminal part translocates to mitochondria where it triggers cytochrome c release. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined. [provided by RefSeq, Jul 2008]
Chromosome	22
Cytoband	q11.21
Chromosome location (bp)	17734138 - 17774770
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000015475 (version 78.38)
Entrez gene	637
UniProt	P55957 (UniProt - Evidence at protein level)
neXtProt	NX_P55957
Antibodypedia	BID antibodies

PROTEIN BROWSER

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ENST00000317361		ENST00000342111		ENST00000399765		ENST00000399767		ENST00000399774		ENST00000551952		ENST00000611040		ENST00000614949		ENST00000615414		ENST00000617586		ENST00000622694

PROTEIN INFORMATION

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Splice variant	Ensembl	UniProt	Protein class	Gene ontology	Length (aa)	Molecular mass (kDa)	Signal peptide (predicted)
BID-001	ENSP00000382674 ENST00000399774	P55957 Show all » « Hide P55957 [Direct mapping] BH3-interacting domain death agonist BH3-interacting domain death agonist p15 BH3-interacting domain death agonist p13 BH3-interacting domain death agonist p11 A8ASI8 [Target identity:100%; Query identity:100%] BH3 interacting domain death agonist, isoform CRA_d {ECO:0000313\|EMBL:EAW57773.1}; BID isoform L(2) {ECO:0000313\|EMBL:ACD47108.1}; Desmocollin type 4 {ECO:0000313\|EMBL:BAF79673.1}; cDNA, FLJ94329, Homo sapiens BH3 interacting domain death agonist (BID), mRNA {ECO:0000313\|EMBL:BAG36471.1} B1PL87 [Target identity:69%; Query identity:100%] Bid {ECO:0000313\|EMBL:ACA61804.1} B2ZP79 [Target identity:50%; Query identity:100%] BH3 interacting domain death agonist, isoform CRA_b {ECO:0000313\|EMBL:EAW57771.1}; BID isoform ES(1b) {ECO:0000313\|EMBL:ACD47107.1}	Show » « Hide Predicted intracellular proteins Mitochondrial proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)	Show » « Hide GO:0001836 [release of cytochrome c from mitochondria] GO:0005123 [death receptor binding] GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0005739 [mitochondrion] GO:0005741 [mitochondrial outer membrane] GO:0005829 [cytosol] GO:0006915 [apoptotic process] GO:0008625 [extrinsic apoptotic signaling pathway via death domain receptors] GO:0008637 [apoptotic mitochondrial changes] GO:0016020 [membrane] GO:0032461 [positive regulation of protein oligomerization] GO:0032464 [positive regulation of protein homooligomerization] GO:0042770 [signal transduction in response to DNA damage] GO:0043065 [positive regulation of apoptotic process] GO:0051402 [neuron apoptotic process] GO:0070062 [extracellular vesicular exosome] GO:0090150 [establishment of protein localization to membrane] GO:0090200 [positive regulation of release of cytochrome c from mitochondria] GO:0097193 [intrinsic apoptotic signaling pathway] GO:1900740 [positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway] GO:1901030 [positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway] GO:2001238 [positive regulation of extrinsic apoptotic signaling pathway] GO:2001244 [positive regulation of intrinsic apoptotic signaling pathway]	195	22	No
BID-002	ENSP00000318822 ENST00000317361	P55957 Show all » « Hide P55957 [Direct mapping] BH3-interacting domain death agonist BH3-interacting domain death agonist p15 BH3-interacting domain death agonist p13 BH3-interacting domain death agonist p11 A8ASI8 [Target identity:80%; Query identity:100%] BH3 interacting domain death agonist, isoform CRA_d {ECO:0000313\|EMBL:EAW57773.1}; BID isoform L(2) {ECO:0000313\|EMBL:ACD47108.1}; Desmocollin type 4 {ECO:0000313\|EMBL:BAF79673.1}; cDNA, FLJ94329, Homo sapiens BH3 interacting domain death agonist (BID), mRNA {ECO:0000313\|EMBL:BAG36471.1} B1PL87 [Target identity:56%; Query identity:100%] Bid {ECO:0000313\|EMBL:ACA61804.1} B2ZP79 [Target identity:41%; Query identity:100%] BH3 interacting domain death agonist, isoform CRA_b {ECO:0000313\|EMBL:EAW57771.1}; BID isoform ES(1b) {ECO:0000313\|EMBL:ACD47107.1}	Show » « Hide Predicted intracellular proteins Mitochondrial proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)	Show » « Hide GO:0001836 [release of cytochrome c from mitochondria] GO:0005123 [death receptor binding] GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0005739 [mitochondrion] GO:0005741 [mitochondrial outer membrane] GO:0005829 [cytosol] GO:0006626 [protein targeting to mitochondrion] GO:0006915 [apoptotic process] GO:0006919 [activation of cysteine-type endopeptidase activity involved in apoptotic process] GO:0007420 [brain development] GO:0008625 [extrinsic apoptotic signaling pathway via death domain receptors] GO:0008637 [apoptotic mitochondrial changes] GO:0016020 [membrane] GO:0031625 [ubiquitin protein ligase binding] GO:0032355 [response to estradiol] GO:0032459 [regulation of protein oligomerization] GO:0032461 [positive regulation of protein oligomerization] GO:0032464 [positive regulation of protein homooligomerization] GO:0032592 [integral component of mitochondrial membrane] GO:0034349 [glial cell apoptotic process] GO:0042127 [regulation of cell proliferation] GO:0042770 [signal transduction in response to DNA damage] GO:0043065 [positive regulation of apoptotic process] GO:0051260 [protein homooligomerization] GO:0051402 [neuron apoptotic process] GO:0070062 [extracellular vesicular exosome] GO:0090150 [establishment of protein localization to membrane] GO:0090200 [positive regulation of release of cytochrome c from mitochondria] GO:0097191 [extrinsic apoptotic signaling pathway] GO:0097193 [intrinsic apoptotic signaling pathway] GO:0097284 [hepatocyte apoptotic process] GO:0097345 [mitochondrial outer membrane permeabilization] GO:1900740 [positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway] GO:1901030 [positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway] GO:1902108 [regulation of mitochondrial membrane permeability involved in apoptotic process] GO:2000045 [regulation of G1/S transition of mitotic cell cycle] GO:2001238 [positive regulation of extrinsic apoptotic signaling pathway] GO:2001244 [positive regulation of intrinsic apoptotic signaling pathway]	241	26.8	No
BID-003	ENSP00000344594 ENST00000342111	P55957 Show all » « Hide P55957 [Direct mapping] BH3-interacting domain death agonist BH3-interacting domain death agonist p15 BH3-interacting domain death agonist p13 BH3-interacting domain death agonist p11	Show » « Hide Predicted intracellular proteins Mitochondrial proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)	Show » « Hide GO:0001836 [release of cytochrome c from mitochondria] GO:0005123 [death receptor binding] GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0005739 [mitochondrion] GO:0005741 [mitochondrial outer membrane] GO:0005829 [cytosol] GO:0006915 [apoptotic process] GO:0008625 [extrinsic apoptotic signaling pathway via death domain receptors] GO:0008637 [apoptotic mitochondrial changes] GO:0016020 [membrane] GO:0032461 [positive regulation of protein oligomerization] GO:0032464 [positive regulation of protein homooligomerization] GO:0042770 [signal transduction in response to DNA damage] GO:0043065 [positive regulation of apoptotic process] GO:0051402 [neuron apoptotic process] GO:0070062 [extracellular vesicular exosome] GO:0090150 [establishment of protein localization to membrane] GO:0090200 [positive regulation of release of cytochrome c from mitochondria] GO:0097193 [intrinsic apoptotic signaling pathway] GO:1900740 [positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway] GO:1901030 [positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway] GO:2001238 [positive regulation of extrinsic apoptotic signaling pathway] GO:2001244 [positive regulation of intrinsic apoptotic signaling pathway]	137	14.6	No
BID-004	ENSP00000382667 ENST00000399765	P55957 Show all » « Hide P55957 [Direct mapping] BH3-interacting domain death agonist BH3-interacting domain death agonist p15 BH3-interacting domain death agonist p13 BH3-interacting domain death agonist p11 B2ZP79 [Target identity:100%; Query identity:100%] BH3 interacting domain death agonist, isoform CRA_b {ECO:0000313\|EMBL:EAW57771.1}; BID isoform ES(1b) {ECO:0000313\|EMBL:ACD47107.1}	Show » « Hide Predicted intracellular proteins Mitochondrial proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)	Show » « Hide GO:0001836 [release of cytochrome c from mitochondria] GO:0005123 [death receptor binding] GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0005739 [mitochondrion] GO:0005741 [mitochondrial outer membrane] GO:0005829 [cytosol] GO:0006915 [apoptotic process] GO:0008625 [extrinsic apoptotic signaling pathway via death domain receptors] GO:0008637 [apoptotic mitochondrial changes] GO:0016020 [membrane] GO:0032461 [positive regulation of protein oligomerization] GO:0032464 [positive regulation of protein homooligomerization] GO:0042770 [signal transduction in response to DNA damage] GO:0043065 [positive regulation of apoptotic process] GO:0051402 [neuron apoptotic process] GO:0070062 [extracellular vesicular exosome] GO:0090150 [establishment of protein localization to membrane] GO:0090200 [positive regulation of release of cytochrome c from mitochondria] GO:0097193 [intrinsic apoptotic signaling pathway] GO:1900740 [positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway] GO:1901030 [positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway] GO:2001238 [positive regulation of extrinsic apoptotic signaling pathway] GO:2001244 [positive regulation of intrinsic apoptotic signaling pathway]	99	11.3	No
BID-009	ENSP00000449236 ENST00000551952	P55957 Show all » « Hide P55957 [Direct mapping] BH3-interacting domain death agonist BH3-interacting domain death agonist p15 BH3-interacting domain death agonist p13 BH3-interacting domain death agonist p11 A8ASI8 [Target identity:100%; Query identity:100%] BH3 interacting domain death agonist, isoform CRA_d {ECO:0000313\|EMBL:EAW57773.1}; BID isoform L(2) {ECO:0000313\|EMBL:ACD47108.1}; Desmocollin type 4 {ECO:0000313\|EMBL:BAF79673.1}; cDNA, FLJ94329, Homo sapiens BH3 interacting domain death agonist (BID), mRNA {ECO:0000313\|EMBL:BAG36471.1} B1PL87 [Target identity:69%; Query identity:100%] Bid {ECO:0000313\|EMBL:ACA61804.1} B2ZP79 [Target identity:50%; Query identity:100%] BH3 interacting domain death agonist, isoform CRA_b {ECO:0000313\|EMBL:EAW57771.1}; BID isoform ES(1b) {ECO:0000313\|EMBL:ACD47107.1}	Show » « Hide Predicted intracellular proteins Mitochondrial proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)	Show » « Hide GO:0001836 [release of cytochrome c from mitochondria] GO:0005123 [death receptor binding] GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0005739 [mitochondrion] GO:0005741 [mitochondrial outer membrane] GO:0005829 [cytosol] GO:0006915 [apoptotic process] GO:0008625 [extrinsic apoptotic signaling pathway via death domain receptors] GO:0008637 [apoptotic mitochondrial changes] GO:0016020 [membrane] GO:0032461 [positive regulation of protein oligomerization] GO:0032464 [positive regulation of protein homooligomerization] GO:0042770 [signal transduction in response to DNA damage] GO:0043065 [positive regulation of apoptotic process] GO:0051402 [neuron apoptotic process] GO:0070062 [extracellular vesicular exosome] GO:0090150 [establishment of protein localization to membrane] GO:0090200 [positive regulation of release of cytochrome c from mitochondria] GO:0097193 [intrinsic apoptotic signaling pathway] GO:1900740 [positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway] GO:1901030 [positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway] GO:2001238 [positive regulation of extrinsic apoptotic signaling pathway] GO:2001244 [positive regulation of intrinsic apoptotic signaling pathway]	195	22	No
BID-201	ENSP00000382669 ENST00000399767	P55957 Show all » « Hide P55957 [Direct mapping] BH3-interacting domain death agonist BH3-interacting domain death agonist p15 BH3-interacting domain death agonist p13 BH3-interacting domain death agonist p11 B2ZP79 [Target identity:100%; Query identity:100%] BH3 interacting domain death agonist, isoform CRA_b {ECO:0000313\|EMBL:EAW57771.1}; BID isoform ES(1b) {ECO:0000313\|EMBL:ACD47107.1}	Show » « Hide Predicted intracellular proteins Mitochondrial proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)	Show » « Hide GO:0001836 [release of cytochrome c from mitochondria] GO:0005123 [death receptor binding] GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0005739 [mitochondrion] GO:0005741 [mitochondrial outer membrane] GO:0005829 [cytosol] GO:0006915 [apoptotic process] GO:0008625 [extrinsic apoptotic signaling pathway via death domain receptors] GO:0008637 [apoptotic mitochondrial changes] GO:0016020 [membrane] GO:0032461 [positive regulation of protein oligomerization] GO:0032464 [positive regulation of protein homooligomerization] GO:0042770 [signal transduction in response to DNA damage] GO:0043065 [positive regulation of apoptotic process] GO:0051402 [neuron apoptotic process] GO:0070062 [extracellular vesicular exosome] GO:0090150 [establishment of protein localization to membrane] GO:0090200 [positive regulation of release of cytochrome c from mitochondria] GO:0097193 [intrinsic apoptotic signaling pathway] GO:1900740 [positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway] GO:1901030 [positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway] GO:2001238 [positive regulation of extrinsic apoptotic signaling pathway] GO:2001244 [positive regulation of intrinsic apoptotic signaling pathway]	99	11.3	No
BID-202	ENSP00000483709 ENST00000611040	P55957 Show all » « Hide P55957 [Direct mapping] BH3-interacting domain death agonist BH3-interacting domain death agonist p15 BH3-interacting domain death agonist p13 BH3-interacting domain death agonist p11 B2ZP79 [Target identity:100%; Query identity:100%] BH3 interacting domain death agonist, isoform CRA_b {ECO:0000313\|EMBL:EAW57771.1}; BID isoform ES(1b) {ECO:0000313\|EMBL:ACD47107.1}	Show » « Hide Predicted intracellular proteins Mitochondrial proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)	Show » « Hide GO:0001836 [release of cytochrome c from mitochondria] GO:0005123 [death receptor binding] GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0005739 [mitochondrion] GO:0005741 [mitochondrial outer membrane] GO:0005829 [cytosol] GO:0006915 [apoptotic process] GO:0008625 [extrinsic apoptotic signaling pathway via death domain receptors] GO:0008637 [apoptotic mitochondrial changes] GO:0016020 [membrane] GO:0032461 [positive regulation of protein oligomerization] GO:0032464 [positive regulation of protein homooligomerization] GO:0042770 [signal transduction in response to DNA damage] GO:0043065 [positive regulation of apoptotic process] GO:0051402 [neuron apoptotic process] GO:0070062 [extracellular vesicular exosome] GO:0090150 [establishment of protein localization to membrane] GO:0090200 [positive regulation of release of cytochrome c from mitochondria] GO:0097193 [intrinsic apoptotic signaling pathway] GO:1900740 [positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway] GO:1901030 [positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway] GO:2001238 [positive regulation of extrinsic apoptotic signaling pathway] GO:2001244 [positive regulation of intrinsic apoptotic signaling pathway]	99	11.3	No
BID-203	ENSP00000477773 ENST00000614949	P55957 Show all » « Hide P55957 [Direct mapping] BH3-interacting domain death agonist BH3-interacting domain death agonist p15 BH3-interacting domain death agonist p13 BH3-interacting domain death agonist p11 B2ZP79 [Target identity:100%; Query identity:100%] BH3 interacting domain death agonist, isoform CRA_b {ECO:0000313\|EMBL:EAW57771.1}; BID isoform ES(1b) {ECO:0000313\|EMBL:ACD47107.1}	Show » « Hide Predicted intracellular proteins Mitochondrial proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)	Show » « Hide GO:0001836 [release of cytochrome c from mitochondria] GO:0005123 [death receptor binding] GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0005739 [mitochondrion] GO:0005741 [mitochondrial outer membrane] GO:0005829 [cytosol] GO:0006915 [apoptotic process] GO:0008625 [extrinsic apoptotic signaling pathway via death domain receptors] GO:0008637 [apoptotic mitochondrial changes] GO:0016020 [membrane] GO:0032461 [positive regulation of protein oligomerization] GO:0032464 [positive regulation of protein homooligomerization] GO:0042770 [signal transduction in response to DNA damage] GO:0043065 [positive regulation of apoptotic process] GO:0051402 [neuron apoptotic process] GO:0070062 [extracellular vesicular exosome] GO:0090150 [establishment of protein localization to membrane] GO:0090200 [positive regulation of release of cytochrome c from mitochondria] GO:0097193 [intrinsic apoptotic signaling pathway] GO:1900740 [positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway] GO:1901030 [positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway] GO:2001238 [positive regulation of extrinsic apoptotic signaling pathway] GO:2001244 [positive regulation of intrinsic apoptotic signaling pathway]	99	11.3	No
BID-204	ENSP00000483534 ENST00000615414	P55957 Show all » « Hide P55957 [Direct mapping] BH3-interacting domain death agonist BH3-interacting domain death agonist p15 BH3-interacting domain death agonist p13 BH3-interacting domain death agonist p11 B2ZP79 [Target identity:100%; Query identity:100%] BH3 interacting domain death agonist, isoform CRA_b {ECO:0000313\|EMBL:EAW57771.1}; BID isoform ES(1b) {ECO:0000313\|EMBL:ACD47107.1}	Show » « Hide Predicted intracellular proteins Mitochondrial proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)	Show » « Hide GO:0001836 [release of cytochrome c from mitochondria] GO:0005123 [death receptor binding] GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0005739 [mitochondrion] GO:0005741 [mitochondrial outer membrane] GO:0005829 [cytosol] GO:0006915 [apoptotic process] GO:0008625 [extrinsic apoptotic signaling pathway via death domain receptors] GO:0008637 [apoptotic mitochondrial changes] GO:0016020 [membrane] GO:0032461 [positive regulation of protein oligomerization] GO:0032464 [positive regulation of protein homooligomerization] GO:0042770 [signal transduction in response to DNA damage] GO:0043065 [positive regulation of apoptotic process] GO:0051402 [neuron apoptotic process] GO:0070062 [extracellular vesicular exosome] GO:0090150 [establishment of protein localization to membrane] GO:0090200 [positive regulation of release of cytochrome c from mitochondria] GO:0097193 [intrinsic apoptotic signaling pathway] GO:1900740 [positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway] GO:1901030 [positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway] GO:2001238 [positive regulation of extrinsic apoptotic signaling pathway] GO:2001244 [positive regulation of intrinsic apoptotic signaling pathway]	99	11.3	No
BID-205	ENSP00000481991 ENST00000617586	B2ZP78 Show all » « Hide B2ZP78 [Target identity:100%; Query identity:100%] BID isoform Si6 {ECO:0000313\|EMBL:ACD47106.1}	Show » « Hide Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)	Show » « Hide GO:0005737 [cytoplasm] GO:0043065 [positive regulation of apoptotic process]	122	13	No
BID-206	ENSP00000480414 ENST00000622694	P55957 Show all » « Hide P55957 [Direct mapping] BH3-interacting domain death agonist BH3-interacting domain death agonist p15 BH3-interacting domain death agonist p13 BH3-interacting domain death agonist p11 A8ASI8 [Target identity:100%; Query identity:100%] BH3 interacting domain death agonist, isoform CRA_d {ECO:0000313\|EMBL:EAW57773.1}; BID isoform L(2) {ECO:0000313\|EMBL:ACD47108.1}; Desmocollin type 4 {ECO:0000313\|EMBL:BAF79673.1}; cDNA, FLJ94329, Homo sapiens BH3 interacting domain death agonist (BID), mRNA {ECO:0000313\|EMBL:BAG36471.1} B1PL87 [Target identity:69%; Query identity:100%] Bid {ECO:0000313\|EMBL:ACA61804.1} B2ZP79 [Target identity:50%; Query identity:100%] BH3 interacting domain death agonist, isoform CRA_b {ECO:0000313\|EMBL:EAW57771.1}; BID isoform ES(1b) {ECO:0000313\|EMBL:ACD47107.1}	Show » « Hide Predicted intracellular proteins Mitochondrial proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)	Show » « Hide GO:0001836 [release of cytochrome c from mitochondria] GO:0005123 [death receptor binding] GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0005739 [mitochondrion] GO:0005741 [mitochondrial outer membrane] GO:0005829 [cytosol] GO:0006915 [apoptotic process] GO:0008625 [extrinsic apoptotic signaling pathway via death domain receptors] GO:0008637 [apoptotic mitochondrial changes] GO:0016020 [membrane] GO:0032461 [positive regulation of protein oligomerization] GO:0032464 [positive regulation of protein homooligomerization] GO:0042770 [signal transduction in response to DNA damage] GO:0043065 [positive regulation of apoptotic process] GO:0051402 [neuron apoptotic process] GO:0070062 [extracellular vesicular exosome] GO:0090150 [establishment of protein localization to membrane] GO:0090200 [positive regulation of release of cytochrome c from mitochondria] GO:0097193 [intrinsic apoptotic signaling pathway] GO:1900740 [positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway] GO:1901030 [positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway] GO:2001238 [positive regulation of extrinsic apoptotic signaling pathway] GO:2001244 [positive regulation of intrinsic apoptotic signaling pathway]	195	22	No

The Human Protein Atlas project is funded by the Knut & Alice Wallenberg foundation.

Protein class

Predicted localization

Number of transcripts

RNA tissue category

Protein evidence

Protein localization

Data reliability description

Data reliability

RNA expression (FPKM)

Protein expression (score)

HPA dataset

RNA tissue category HPA

GTEx dataset

RNA tissue category GTEx