Gene Gene synonym Ensembl Gene description Chromosome Position Protein class Evidence summary HPA evidence UniProt evidence MS evidence Antibody Reliability (IH) Reliability (Mouse Brain) Reliability (IF) Subcellular location RNA tissue category RNA TS RNA TS FPKM FPKM max in non-specific ACVR1 ACVR1A, ACVRLK2, ALK2, SKR1 ENSG00000115170 Activin A receptor, type I 2 157736444-157875862 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA007505, HPA046514 Uncertain Uncertain Nucleoli, Cytoplasm Expressed in all thyroid gland: 37.7 ACVR1B ActRIB, ACVRLK4, ALK4, SKR2 ENSG00000135503 Activin A receptor, type IB 12 51951667-51997078 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB026126, HPA063761 Uncertain Supportive Cytoplasm Expressed in all kidney: 27.0 ACVR1C ACVRLK7, ALK7 ENSG00000123612 Activin A receptor, type IC 2 157526767-157629005 Enzymes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA007982, HPA011933 Uncertain Uncertain Cytoplasm, Cytoskeleton (Intermediate filaments), Cytoskeleton (Microtubules) Tissue enriched 7 adipose tissue: 22.9 duodenum: 3.4 ACVR2A ACTRII, ACVR2 ENSG00000121989 Activin A receptor, type IIA 2 147844517-147930826 Cancer-related genes, Enzymes, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA046997 Uncertain Uncertain Cytoplasm Expressed in all skin: 14.0 ACVR2B ActR-IIB ENSG00000114739 Activin A receptor, type IIB 3 38453851-38493142 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA007398, CAB025115 Uncertain Uncertain Nucleus, Cytoplasm Mixed testis: 2.7 ACVRL1 ACVRLK1, ALK1, HHT, HHT2, ORW2 ENSG00000139567 Activin A receptor type II-like 1 12 51906908-51923361 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA007041 Uncertain Tissue enhanced 0 placenta: 69.3 lung: 56.2 ANKK1 X-kinase ENSG00000170209 Ankyrin repeat and kinase domain containing 1 11 113387791-113400418 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA012813 Uncertain Tissue enhanced 0 skin: 2.4 fallopian tube: 0.8 ARAF ARAF1 ENSG00000078061 A-Raf proto-oncogene, serine/threonine kinase X 47561100-47571920 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA046188, HPA066326 Uncertain Supportive Nucleoli, Nucleus, Nuclear membrane Expressed in all bone marrow: 40.1 BMPR1A ACVRLK3, ALK3, CD292 ENSG00000107779 Bone morphogenetic protein receptor, type IA 10 86756650-86932838 Cancer-related genes, CD markers, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB019398 Uncertain Uncertain Cytoplasm Mixed thyroid gland: 13.9 BMPR1B ALK6, CDw293 ENSG00000138696 Bone morphogenetic protein receptor, type IB 4 94757968-95158448 CD markers, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level CAB009634 Uncertain Tissue enhanced 0 fallopian tube: 14.5;prostate: 23.5 cerebral cortex: 9.6 BMPR2 BMPR-II, BMPR3, BRK-3, PPH1, T-ALK ENSG00000204217 Bone morphogenetic protein receptor, type II (serine/threonine kinase) 2 202376936-202567751 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA017385, HPA049014 Uncertain Uncertain Nucleus but not nucleoli, Plasma membrane Expressed in all lung: 23.1 BRAF BRAF1 ENSG00000157764 B-Raf proto-oncogene, serine/threonine kinase 7 140719327-140924764 Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001328, CAB004552, HPA071048 Uncertain Uncertain Vesicles, Cytoplasm Expressed in all testis: 18.6 ILK ENSG00000166333 Integrin-linked kinase 11 6603708-6610874 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004041, HPA048437 Supportive Supportive Focal Adhesions, Cell Junctions Expressed in all smooth muscle: 306.9 IRAK1 IRAK, pelle ENSG00000184216 Interleukin-1 receptor-associated kinase 1 X 154010500-154019980 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004461, HPA054476 Supportive Supportive Cytoplasm, Nucleus Expressed in all bone marrow: 38.6 IRAK2 ENSG00000134070 Interleukin-1 receptor-associated kinase 2 3 10164865-10243743 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB013483, HPA050520 Uncertain Mixed bone marrow: 11.4 IRAK3 IRAK-M ENSG00000090376 Interleukin-1 receptor-associated kinase 3 12 66188879-66254622 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA043097 Uncertain Uncertain Vesicles Tissue enhanced 0 bone marrow: 33.3 spleen: 11.7 IRAK4 NY-REN-64 ENSG00000198001 Interleukin-1 receptor-associated kinase 4 12 43758944-43789543 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000924, CAB016685, CAB022077 Uncertain Supportive Cytoskeleton (Microtubules), Nucleoli, Plasma membrane, Cytoplasm Expressed in all lymph node: 18.9 KSR1 KSR, RSU2 ENSG00000141068 Kinase suppressor of ras 1 17 27456714-27626438 Enzymes, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB009623, HPA011215 Supportive Expressed in all placenta: 41.2 KSR2 FLJ25965 ENSG00000171435 Kinase suppressor of ras 2 12 117453012-117968983 Enzymes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA035536 Uncertain Tissue enhanced 0 cerebral cortex: 2.1 adrenal gland: 0.7 LIMK1 LIMK ENSG00000106683 LIM domain kinase 1 7 74082933-74122525 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028064, HPA028516 Uncertain Supportive Nucleus but not nucleoli, Cytoplasm Expressed in all lymph node: 19.6 LIMK2 ENSG00000182541 LIM domain kinase 2 22 31212239-31280080 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008183, CAB019313, HPA053882 Uncertain Expressed in all placenta: 42.6 LRRK1 FLJ23119, KIAA1790, RIPK6, Roco1 ENSG00000154237 Leucine-rich repeat kinase 1 15 100919215-101078254 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA010537 Uncertain Supportive Cytoplasm, Mitochondria Mixed lymph node: 9.0 LRRK2 DKFZp434H2111, FLJ45829, PARK8, RIPK7, ROCO2 ENSG00000188906 Leucine-rich repeat kinase 2 12 40196744-40369285 Cancer-related genes, Disease related genes, Enzymes, Mitochondrial proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA014293, CAB037160 Uncertain Tissue enhanced 0 lung: 36.1 appendix: 9.0 RAF1 c-Raf, CRAF, Raf-1 ENSG00000132155 Raf-1 proto-oncogene, serine/threonine kinase 3 12583601-12664226 Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002640, CAB019291 Uncertain Uncertain Nucleus but not nucleoli Expressed in all heart muscle: 47.9 RIPK1 RIP ENSG00000137275 Receptor (TNFRSF)-interacting serine-threonine kinase 1 6 3063991-3115187 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB010302, HPA015257 Supportive Supportive Plasma membrane, Cytoplasm Expressed in all rectum: 15.7 RIPK2 CARD3, CARDIAK, RICK, RIP2 ENSG00000104312 Receptor-interacting serine-threonine kinase 2 8 89757747-89791063 Cytoskeleton related proteins, Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA015273, HPA016499 Supportive Supportive Cytoplasm Mixed gallbladder: 7.9 RIPK3 RIP3 ENSG00000129465 Receptor-interacting serine-threonine kinase 3 14 24336021-24340045 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA055087 Uncertain Mixed small intestine: 15.7 RIPK4 ANKK2, ANKRD3, DIK, PKK, RIP4 ENSG00000183421 Receptor-interacting serine-threonine kinase 4 21 41739369-41767106 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA021158 Uncertain Tissue enhanced 0 esophagus: 22.9 kidney: 10.8 TESK1 ENSG00000107140 Testis-specific kinase 1 9 35605305-35610041 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA017064 Uncertain Expressed in all testis: 29.8 TESK2 ENSG00000070759 Testis-specific kinase 2 1 45343883-45491166 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA027257 Uncertain Supportive Nucleus but not nucleoli Expressed in all prostate: 14.0 TGFBR1 ACVRLK4, ALK-5, ESS1, MSSE ENSG00000106799 Transforming growth factor, beta receptor 1 9 99104038-99154192 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002441, CAB031481 Uncertain Expressed in all placenta: 33.5 TGFBR2 MFS2 ENSG00000163513 Transforming growth factor, beta receptor II (70/80kDa) 3 30606502-30694142 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB073537 Supportive Plasma membrane Expressed in all adipose tissue: 187.4