Gene Gene synonym Ensembl Gene description Chromosome Position Protein class Evidence summary HPA evidence UniProt evidence MS evidence Antibody Reliability (IH) Reliability (Mouse Brain) Reliability (IF) Subcellular location RNA tissue category RNA TS RNA TS FPKM FPKM max in non-specific AASS LKRSDH, LORSDH ENSG00000008311 Aminoadipate-semialdehyde synthase 7 122075647-122144280 Disease related genes, Enzymes, Mitochondrial proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA020637, HPA020728, HPA020734 Supportive Supportive Mitochondria, Vesicles Expressed in all ovary: 19.4 ACADM ACAD1, MCAD, MCADH ENSG00000117054 Acyl-CoA dehydrogenase, C-4 to C-12 straight chain 1 75724347-75787575 Disease related genes, Enzymes, Mitochondrial proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006198, HPA026542 Supportive Supportive Mitochondria Expressed in all kidney: 163.5 ACADS ACAD3, SCAD ENSG00000122971 Acyl-CoA dehydrogenase, C-2 to C-3 short chain 12 120725735-120740008 Disease related genes, Enzymes, Mitochondrial proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA004799, CAB019284, HPA022271 Supportive Supportive Nucleus but not nucleoli, Centrosome Expressed in all duodenum: 56.0 ACADVL ACAD6, LCACD, VLCAD ENSG00000072778 Acyl-CoA dehydrogenase, very long chain 17 7217125-7225273 Disease related genes, Enzymes, Mitochondrial proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019006, HPA020595 Supportive Supportive Nucleus, Mitochondria, Nucleoli Expressed in all adrenal gland: 298.3 ACOX1 PALMCOX ENSG00000161533 Acyl-CoA oxidase 1, palmitoyl 17 75941507-75979363 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB021094, HPA021192, HPA021195, HPA028759 Supportive Supportive Nucleus, Vesicles Expressed in all liver: 79.6 ADH1A ADH1 ENSG00000187758 Alcohol dehydrogenase 1A (class I), alpha polypeptide 4 99276367-99291028 Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB009562, HPA047814, HPA060902 Supportive Tissue enriched 118 liver: 747.4 gallbladder: 6.3 ADH1B ADH2 ENSG00000196616 Alcohol dehydrogenase 1B (class I), beta polypeptide 4 99304964-99321442 Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA047814, HPA060902 Supportive Group enriched 6 adipose tissue: 863.8;liver: 1586.7 lung: 201.9 ADH1C ADH3 ENSG00000248144 Alcohol dehydrogenase 1C (class I), gamma polypeptide 4 99336492-99353027 Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA047814, HPA060902 Supportive Group enriched 6 colon: 232.4;duodenum: 395.6;liver: 455.2;rectum: 135.7;small intestine: 122.3;stomach: 332.1 gallbladder: 47.8 ADH4 ADH-2 ENSG00000198099 Alcohol dehydrogenase 4 (class II), pi polypeptide 4 99123657-99157792 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA020525 Supportive Uncertain Nucleus, Cytoplasm Tissue enriched 12 liver: 1534.9 duodenum: 124.6 ADH7 ADH-4 ENSG00000196344 Alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide 4 99412261-99435737 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039695 Supportive Tissue enriched 5 esophagus: 162.6 tonsil: 32.0 ADO C10orf22, FLJ14547 ENSG00000181915 2-aminoethanethiol (cysteamine) dioxygenase 10 62804857-62808483 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039194, HPA040437 Supportive Expressed in all testis: 32.9 AKR1B1 ALDR1, AR ENSG00000085662 Aldo-keto reductase family 1, member B1 (aldose reductase) 7 134442350-134459284 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB018773, HPA026425, CAB027391, CAB047353, HPA052751 Supportive Supportive Nucleus but not nucleoli, Cytoplasm Tissue enriched 9 adrenal gland: 1545.4 placenta: 174.2 AKR1D1 SRD5B1 ENSG00000122787 Aldo-keto reductase family 1, member D1 7 138002324-138117986 Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA057002 Supportive Supportive Nucleus but not nucleoli Tissue enriched 137 liver: 165.3 testis: 1.2 AKR7A2 AFAR ENSG00000053371 Aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) 1 19303965-19312146 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB032587, CAB032841 Supportive Supportive Cytoplasm Expressed in all kidney: 63.6 ALDH18A1 GSAS, P5CS, PYCS ENSG00000059573 Aldehyde dehydrogenase 18 family, member A1 10 95605929-95656706 Disease related genes, Enzymes, Mitochondrial proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008333, HPA012604 Supportive Supportive Mitochondria Expressed in all duodenum: 65.5 ALDH1A1 ALDH1, PUMB1, RALDH1 ENSG00000165092 Aldehyde dehydrogenase 1 family, member A1 9 72900662-73080442 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002123, CAB020690 Supportive Expressed in all liver: 481.9 ALDH3A1 ALDH3 ENSG00000108602 Aldehyde dehydrogenase 3 family, member A1 17 19737984-19748943 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB045957, HPA051150, HPA063783 Supportive Supportive Plasma membrane, Cytoplasm, Vesicles Tissue enhanced 0 esophagus: 301.4;stomach: 169.0 skin: 49.0 ALDH4A1 ALDH4, P5CDh ENSG00000159423 Aldehyde dehydrogenase 4 family, member A1 1 18871430-18902781 Disease related genes, Enzymes, Mitochondrial proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004645, HPA006401 Supportive Uncertain Cytoplasm Expressed in all kidney: 176.5 ALDH5A1 SSADH, SSDH ENSG00000112294 Aldehyde dehydrogenase 5 family, member A1 6 24494852-24537207 Disease related genes, Enzymes, Mitochondrial proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA029715, HPA029716 Supportive Supportive Mitochondria Expressed in all liver: 33.5 ALDH6A1 MMSDH ENSG00000119711 Aldehyde dehydrogenase 6 family, member A1 14 74056850-74084493 Disease related genes, Enzymes, Mitochondrial proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA029072, HPA029073, HPA029074, HPA029075 Supportive Supportive Mitochondria Group enriched 5 kidney: 257.6;liver: 120.0 cerebral cortex: 36.5 ALOX12 12S-LOX ENSG00000108839 Arachidonate 12-lipoxygenase 17 6996065-7010736 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA010691, CAB019287 Supportive Supportive Cytoplasm, Nucleus but not nucleoli Group enriched 8 esophagus: 37.6;skin: 13.8 tonsil: 3.3 AOC3 HPAO, VAP-1, VAP1 ENSG00000131471 Amine oxidase, copper containing 3 17 42851184-42858130 Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000980, CAB025797 Supportive Expressed in all adipose tissue: 286.7 BBOX1 BBH, BBOX, G-BBH, gamma-BBH ENSG00000129151 Butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 11 27040725-27127809 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA007600 Supportive Tissue enriched 5 kidney: 251.6 liver: 49.1 BCKDHA MSU, OVD1A ENSG00000248098 Branched chain keto acid dehydrogenase E1, alpha polypeptide 19 41397460-41431345 Disease related genes, Enzymes, Mitochondrial proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036640 Supportive Expressed in all esophagus: 39.5 BDH1 BDH, SDR9C1 ENSG00000161267 3-hydroxybutyrate dehydrogenase, type 1 3 197509783-197573323 Candidate cardiovascular disease genes, Enzymes, Mitochondrial proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA030947, HPA058709 Supportive Supportive Mitochondria, Nucleus but not nucleoli Expressed in all liver: 123.1 BDH2 DHRS6, FLJ13261, PRO20933, SDR15C1, UCPA-OR, UNQ6308 ENSG00000164039 3-hydroxybutyrate dehydrogenase, type 2 4 103079435-103099883 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036028, HPA036029 Supportive Supportive Cytoplasm Expressed in all kidney: 100.9 BLVRB FLR, SDR43U1 ENSG00000090013 Biliverdin reductase B (flavin reductase (NADPH)) 19 40447789-40465840 Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041698, HPA041937 Supportive Supportive Plasma membrane, Cytoplasm, Nucleus but not nucleoli Expressed in all bone marrow: 295.2 CAT ENSG00000121691 Catalase 11 34438925-34472062 Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB001515, HPA051282, HPA055838 Supportive Supportive Vesicles Expressed in all liver: 373.1 CDO1 ENSG00000129596 Cysteine dioxygenase type 1 5 115804733-115816954 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036573, HPA057503 Supportive Uncertain Nucleus but not nucleoli Tissue enhanced 0 adipose tissue: 68.7;liver: 129.2 placenta: 25.0 CHDH ENSG00000016391 Choline dehydrogenase 3 53812335-53846390 Enzymes, Mitochondrial proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA036633, HPA058130 Supportive Tissue enhanced 0 kidney: 28.4 small intestine: 8.6 CP ENSG00000047457 Ceruloplasmin (ferroxidase) 3 149162410-149222055 Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001834, CAB008591 Supportive Tissue enriched 29 liver: 481.3 urinary bladder: 16.7 CRYL1 GDH, lambda-CRY, MGC149525, MGC149526 ENSG00000165475 Crystallin, lambda 1 13 20403667-20525857 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040403, HPA058848 Supportive Supportive Nucleus, Nucleoli, Plasma membrane, Cytoplasm, Golgi apparatus Expressed in all kidney: 242.3 CRYZ ENSG00000116791 Crystallin, zeta (quinone reductase) 1 74705482-74733408 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021921, HPA023290 Supportive Supportive Cytoplasm Expressed in all kidney: 189.7 CYB5R1 humb5R2, NQO3A2 ENSG00000159348 Cytochrome b5 reductase 1 1 202961869-202967280 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA010641, HPA014147 Supportive Uncertain Nucleoli, Cytoplasm, Mitochondria Expressed in all skeletal muscle: 144.1 CYP11A1 CYP11A, P450SCC ENSG00000140459 Cytochrome P450, family 11, subfamily A, polypeptide 1 15 74337759-74367740 Disease related genes, Enzymes, Mitochondrial proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA016436 Supportive Tissue enriched 9 adrenal gland: 462.1 placenta: 51.9 CYP11B1 CPN1, CYP11B, FHI, P450C11 ENSG00000160882 Cytochrome P450, family 11, subfamily B, polypeptide 1 8 142872356-142879846 Disease related genes, Enzymes, FDA approved drug targets, Mitochondrial proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA049171, HPA056348, HPA057752 Supportive Tissue enriched 891 adrenal gland: 1057.2 testis: 1.1 CYP11B2 ALDOS, CPN2, CYP11B, CYP11BL, P-450C18, P450aldo ENSG00000179142 Cytochrome P450, family 11, subfamily B, polypeptide 2 8 142910559-142917843 Disease related genes, Enzymes, Mitochondrial proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA049171, HPA056348, HPA057752 Supportive Tissue enriched 776 adrenal gland: 77.6 adipose tissue: 0.0 CYP17A1 CPT7, CYP17, P450C17, S17AH ENSG00000148795 Cytochrome P450, family 17, subfamily A, polypeptide 1 10 102830531-102837533 Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA048533 Supportive Tissue enriched 31 adrenal gland: 2857.9 testis: 93.6 CYP19A1 ARO, ARO1, aromatase, CPV1, CYAR, CYP19, P-450AROM ENSG00000137869 Cytochrome P450, family 19, subfamily A, polypeptide 1 15 51208057-51338610 Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB000355, HPA051194 Supportive Uncertain Vesicles Tissue enriched 22 placenta: 145.0 adrenal gland: 6.6 CYP1A2 CP12, P3-450 ENSG00000140505 Cytochrome P450, family 1, subfamily A, polypeptide 2 15 74748844-74756202 Cancer-related genes, Enzymes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB016531 Supportive Tissue enriched 431 liver: 223.1 placenta: 0.5 CYP1B1 CP1B, GLC3A ENSG00000138061 Cytochrome P450, family 1, subfamily B, polypeptide 1 2 38066973-38109902 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB011705, HPA026863 Supportive Mixed fallopian tube: 47.6 CYP21A2 CA21H, CAH1, CPS1, CYP21, CYP21B, P450c21B ENSG00000231852 Cytochrome P450, family 21, subfamily A, polypeptide 2 6 32038265-32041670 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA048979, HPA053371 Supportive Tissue enriched 519 adrenal gland: 443.2 liver: 0.8 CYP24A1 CP24, CYP24, P450-CC24 ENSG00000019186 Cytochrome P450, family 24, subfamily A, polypeptide 1 20 54153449-54173973 Disease related genes, Enzymes, Mitochondrial proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA022261, HPA063771 Supportive Supportive Nucleus but not nucleoli, Mitochondria, Plasma membrane Tissue enhanced 0 endometrium: 11.5;urinary bladder: 40.1 tonsil: 8.0 CYP2A13 CPAD, CYP2A ENSG00000197838 Cytochrome P450, family 2, subfamily A, polypeptide 13 19 41088472-41096195 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA046713, HPA047262 Supportive Tissue enriched 83 liver: 15.8 testis: 0.1 CYP2A7 CYP2A ENSG00000198077 Cytochrome P450, family 2, subfamily A, polypeptide 7 19 40875439-40882752 Enzymes, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB033510, HPA046713, HPA047262 Supportive Tissue enriched 165 liver: 16.5 adipose tissue: 0.0 CYP2C19 CPCJ, CYP2C, P450IIC19 ENSG00000165841 Cytochrome P450, family 2, subfamily C, polypeptide 19 10 94762624-94853260 Cancer-related genes, Enzymes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA015066 Supportive Tissue enhanced 0 duodenum: 33.5;liver: 82.0 small intestine: 15.0 CYP2C8 CPC8 ENSG00000138115 Cytochrome P450, family 2, subfamily C, polypeptide 8 10 95036772-95069497 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA013547, HPA013970, HPA015066 Supportive Tissue enriched 92 liver: 463.4 gallbladder: 5.0 CYP2C9 CYP2C10, P450IIC9 ENSG00000138109 Cytochrome P450, family 2, subfamily C, polypeptide 9 10 94938658-94989390 Enzymes, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA015066, CAB016123 Supportive Tissue enriched 5 liver: 489.0 duodenum: 97.6 CYP2D6 CPD6, CYP2D, CYP2D7AP, CYP2D7BP, CYP2D7P2, CYP2D8P2, CYP2DL1, P450-DB1, P450C2D ENSG00000100197 Cytochrome P450, family 2, subfamily D, polypeptide 6 22 42126499-42130906 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA045223 Supportive Uncertain Golgi apparatus Group enriched 60 duodenum: 15.1;liver: 51.5;small intestine: 18.2 testis: 0.4 CYP2E1 CYP2E ENSG00000130649 Cytochrome P450, family 2, subfamily E, polypeptide 1 10 133520406-133561220 Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA009128, HPA029564 Supportive Tissue enriched 114 liver: 3140.7 tonsil: 27.6 CYP3A4 CYP3A3 ENSG00000160868 Cytochrome P450, family 3, subfamily A, polypeptide 4 7 99756960-99784265 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB033671 Supportive Group enriched 154 duodenum: 629.3;liver: 1056.5;small intestine: 684.5 adrenal gland: 5.1 CYP3A43 ENSG00000021461 Cytochrome P450, family 3, subfamily A, polypeptide 43 7 99828013-99866102 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA066463 Supportive Tissue enriched 11 liver: 3.5 testis: 0.3 CYP4F11 ENSG00000171903 Cytochrome P450, family 4, subfamily F, polypeptide 11 19 15912367-15934867 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA017265, CAB033648, HPA058960 Supportive Tissue enhanced 0 gallbladder: 19.1;liver: 27.7 small intestine: 17.5 CYP4F2 ENSG00000186115 Cytochrome P450, family 4, subfamily F, polypeptide 2 19 15878023-15898120 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA014048, HPA017265, HPA058960 Supportive Group enriched 15 duodenum: 55.3;kidney: 31.1;liver: 78.4;small intestine: 56.1 bone marrow: 3.7 DAO DAMOX ENSG00000110887 D-amino-acid oxidase 12 108858932-108901043 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038653, HPA038654 Supportive Uncertain Nuclear membrane Group enriched 29 kidney: 54.5;liver: 44.0 rectum: 1.7 DCXR DCR, KIDCR, SDR20C1 ENSG00000169738 Dicarbonyl/L-xylulose reductase 17 82035136-82037732 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023371, HPA023863 Supportive Uncertain Nucleoli, Cytoskeleton (Microtubules) Expressed in all liver: 500.7 DDO ENSG00000203797 D-aspartate oxidase 6 110391771-110415562 Enzymes, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA037525, HPA037526 Supportive Supportive Cytoplasm Mixed heart muscle: 10.0 DECR1 DECR, SDR18C1 ENSG00000104325 2,4-dienoyl CoA reductase 1, mitochondrial 8 90001405-90052092 Disease related genes, Enzymes, Mitochondrial proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023160, HPA023162, HPA023238 Supportive Supportive Mitochondria, Cytoplasm Expressed in all liver: 186.0 DHCR24 KIAA0018, seladin-1 ENSG00000116133 24-dehydrocholesterol reductase 1 54849633-54887218 Cytoskeleton related proteins, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB037247, HPA063005 Supportive Expressed in all adrenal gland: 721.4 DHDH HUM2DD ENSG00000104808 Dihydrodiol dehydrogenase (dimeric) 19 48933682-48944969 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA044131 Supportive Uncertain Nucleus but not nucleoli, Cytoskeleton (Actin filaments) Tissue enhanced 0 kidney: 15.2;small intestine: 11.6 duodenum: 5.5 DHODH ENSG00000102967 Dihydroorotate dehydrogenase (quinone) 16 72008588-72027664 Disease related genes, Enzymes, FDA approved drug targets, Mitochondrial proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA010123, HPA011942 Supportive Supportive Nucleus but not nucleoli, Mitochondria Expressed in all liver: 17.6 DHRS3 RDH17, retSDR1, Rsdr1, SDR1, SDR16C1 ENSG00000162496 Dehydrogenase/reductase (SDR family) member 3 1 12567910-12617731 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA010844 Supportive Uncertain Mitochondria, Nucleoli Expressed in all liver: 90.3 DLD DLDH, GCSL, LAD ENSG00000091140 Dihydrolipoamide dehydrogenase 7 107890970-107931730 Citric acid cycle related proteins, Disease related genes, Enzymes, Mitochondrial proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA044849 Supportive Supportive Mitochondria Expressed in all heart muscle: 93.3 DMGDH ENSG00000132837 Dimethylglycine dehydrogenase 5 78997606-79236038 Disease related genes, Enzymes, Mitochondrial proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036441, HPA036442 Supportive Group enriched 17 kidney: 107.7;liver: 82.2 adipose tissue: 5.6 EHHADH ECHD ENSG00000113790 Enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase 3 185190624-185281990 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036401, HPA042021 Supportive Group enriched 7 kidney: 96.5;liver: 128.0 duodenum: 16.2 ETFDH ETFQO ENSG00000171503 Electron-transferring-flavoprotein dehydrogenase 4 158672125-158709623 Disease related genes, Enzymes, Mitochondrial proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041978 Supportive Expressed in all liver: 59.0 ETHE1 HSCO, YF13H12 ENSG00000105755 Ethylmalonic encephalopathy 1 19 43506719-43527244 Cancer-related genes, Disease related genes, Enzymes, Mitochondrial proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028360, HPA029028, HPA029029 Supportive Supportive Mitochondria, Nucleus but not nucleoli Expressed in all rectum: 173.1 FASN FAS, SDR27X1 ENSG00000169710 Fatty acid synthase 17 82078338-82098332 Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB005192, HPA006461, CAB015417, HPA056108 Supportive Supportive Cytoplasm, Plasma membrane Tissue enriched 5 adipose tissue: 170.3 prostate: 32.1 FDXR ADXR ENSG00000161513 Ferredoxin reductase 17 74862497-74873031 Enzymes, Mitochondrial proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB009818, HPA044393, HPA053673 Supportive Tissue enhanced 0 adrenal gland: 126.6 testis: 26.5 FMO3 ENSG00000007933 Flavin containing monooxygenase 3 1 171090877-171117819 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008065, HPA013750 Supportive Uncertain Nucleus but not nucleoli, Cytoplasm, Cytoskeleton (Actin filaments) Tissue enriched 25 liver: 338.8 fallopian tube: 13.3 G6PD G6PD1 ENSG00000160211 Glucose-6-phosphate dehydrogenase X 154531391-154547572 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000247, HPA000834 Supportive Supportive Cytoplasm, Vesicles, Microtubule organizing center, Centrosome Expressed in all testis: 71.9 GAPDH GAPD ENSG00000111640 Glyceraldehyde-3-phosphate dehydrogenase 12 6533927-6538374 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB005197, CAB016392, HPA040067, HPA061280 Supportive Supportive Plasma membrane, Cytoplasm, Nuclear membrane Expressed in all skeletal muscle: 5958.2 GCDH ACAD5 ENSG00000105607 Glutaryl-CoA dehydrogenase 19 12891026-12914207 Disease related genes, Enzymes, Mitochondrial proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043252, HPA048492 Supportive Supportive Mitochondria Expressed in all liver: 37.4 GLDC GCSP, NKH ENSG00000178445 Glycine dehydrogenase (decarboxylating) 9 6532464-6645650 Disease related genes, Enzymes, Mitochondrial proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002318, HPA052887 Supportive Supportive Mitochondria, Nucleus Tissue enhanced 0 kidney: 19.2;liver: 11.4;placenta: 12.5 cerebral cortex: 4.5 GPD2 ENSG00000115159 Glycerol-3-phosphate dehydrogenase 2 (mitochondrial) 2 156435290-156613735 Enzymes, Mitochondrial proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008012, HPA045506 Supportive Expressed in all fallopian tube: 21.1 GPX1 ENSG00000233276 Glutathione peroxidase 1 3 49357176-49358600 Cancer-related genes, Enzymes, Mitochondrial proteins, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB011582, HPA044758 Supportive Supportive Cytoplasm Expressed in all adipose tissue: 174.3 GPX8 EPLA847, UNQ847 ENSG00000164294 Glutathione peroxidase 8 (putative) 5 55160118-55167071 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036720, HPA036721 Supportive Supportive Cytoplasm, Cytoskeleton (Actin filaments) Mixed placenta: 27.9 GSR ENSG00000104687 Glutathione reductase 8 30678061-30727926 Cancer-related genes, Enzymes, FDA approved drug targets, Mitochondrial proteins, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001538, CAB008632 Supportive Supportive Cytoplasm, Plasma membrane Expressed in all rectum: 46.8 GSTO1 GSTTLp28, P28 ENSG00000148834 Glutathione S-transferase omega 1 10 104235356-104267459 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA037603, HPA037604 Supportive Expressed in all liver: 183.9 H6PD GDH ENSG00000049239 Hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) 1 9234775-9271337 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA004824, HPA005440 Supportive Uncertain Cytoplasm Expressed in all ovary: 30.3 HAAO ENSG00000162882 3-hydroxyanthranilate 3,4-dioxygenase 2 42767089-42792593 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036394, HPA042024 Supportive Expressed in all liver: 117.4 HADH HADH1, HADHSC, SCHAD ENSG00000138796 Hydroxyacyl-CoA dehydrogenase 4 107989714-108035175 Disease related genes, Enzymes, Mitochondrial proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039588, HPA043888 Supportive Supportive Mitochondria, Nucleus but not nucleoli Expressed in all kidney: 108.2 HAO1 GOX, GOX1 ENSG00000101323 Hydroxyacid oxidase (glycolate oxidase) 1 20 7882981-7940474 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA049552 Supportive Tissue enriched 288 liver: 197.3 kidney: 0.6 HGD AKU, HGO ENSG00000113924 Homogentisate 1,2-dioxygenase 3 120628173-120682571 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA047374, HPA052359 Supportive Uncertain Nucleus, Nucleoli Tissue enhanced 0 kidney: 79.1;liver: 146.1 gallbladder: 46.3 HIBADH NS5ATP1 ENSG00000106049 3-hydroxyisobutyrate dehydrogenase 7 27525442-27662995 Enzymes, Mitochondrial proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019522, HPA021002 Supportive Expressed in all kidney: 58.4 HMGCR ENSG00000113161 3-hydroxy-3-methylglutaryl-CoA reductase 5 75336329-75362104 Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008338, CAB016797 Supportive Expressed in all cerebral cortex: 44.0 HMOX1 bK286B10, HO-1 ENSG00000100292 Heme oxygenase (decycling) 1 22 35380361-35394214 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000635, CAB017444 Supportive Uncertain Plasma membrane, Golgi apparatus Expressed in all spleen: 268.3 HMOX2 HO-2 ENSG00000103415 Heme oxygenase (decycling) 2 16 4474690-4510347 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB025464, HPA040611 Supportive Uncertain Cytoplasm, Vesicles Expressed in all testis: 104.9 HPD 4-HPPD, 4HPPD, GLOD3, PPD ENSG00000158104 4-hydroxyphenylpyruvate dioxygenase 12 121839527-121863596 Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038321, HPA038322 Supportive Uncertain Nucleus but not nucleoli Group enriched 133 kidney: 311.0;liver: 828.9 testis: 4.2 HPGD SDR36C1 ENSG00000164120 Hydroxyprostaglandin dehydrogenase 15-(NAD) 4 174490177-174523154 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA004919, HPA005679 Supportive Supportive Cytoplasm, Nucleus but not nucleoli Tissue enhanced 0 urinary bladder: 334.8 stomach: 140.5 HSD11B1 HSD11, HSD11B, SDR26C1 ENSG00000117594 Hydroxysteroid (11-beta) dehydrogenase 1 1 209686178-209734950 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA047729 Supportive Tissue enriched 6 liver: 331.4 placenta: 59.9 HSD17B1 EDH17B2, EDHB17, HSD17, MGC138140, SDR28C1 ENSG00000108786 Hydroxysteroid (17-beta) dehydrogenase 1 17 42549214-42555213 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021032, HPA065296 Supportive Supportive Cytoplasm, Nucleus but not nucleoli, Nuclear membrane Tissue enriched 50 placenta: 74.1 adipose tissue: 1.4 HSD17B2 HSD17, SDR9C2 ENSG00000086696 Hydroxysteroid (17-beta) dehydrogenase 2 16 82035004-82098534 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021826, HPA050235 Supportive Tissue enhanced 0 duodenum: 321.9;placenta: 288.9 small intestine: 139.3 HSD17B3 SDR12C2 ENSG00000130948 Hydroxysteroid (17-beta) dehydrogenase 3 9 96235306-96302152 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA015307, HPA056833 Supportive Tissue enriched 14 testis: 39.0 small intestine: 2.8 HSD17B4 DBP, MFE-2, SDR8C1 ENSG00000133835 Hydroxysteroid (17-beta) dehydrogenase 4 5 119452443-119637199 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021302, HPA021311, HPA021479 Supportive Supportive Vesicles Expressed in all thyroid gland: 119.8 HSD17B6 HSE, RODH, SDR9C6 ENSG00000025423 Hydroxysteroid (17-beta) dehydrogenase 6 12 56752161-56787790 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA059141 Supportive Tissue enriched 11 liver: 701.4 lung: 61.8 HSD17B8 D6S2245E, FABGL, H2-KE6, HKE6, KE6, RING2, SDR30C1 ENSG00000204228 Hydroxysteroid (17-beta) dehydrogenase 8 6 33204642-33206831 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042132 Supportive Expressed in all thyroid gland: 25.7 HSD3B1 HSD3B, HSDB3, SDR11E1 ENSG00000203857 Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 1 119507198-119515054 Enzymes, FDA approved drug targets, Mitochondrial proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043261, HPA043264, HPA044028 Supportive Tissue enriched 17 placenta: 90.5 small intestine: 5.4 HSD3B2 SDR11E2 ENSG00000203859 Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 1 119414931-119423035 Disease related genes, Enzymes, FDA approved drug targets, Mitochondrial proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043261, HPA043264, HPA044028 Supportive Tissue enriched 557 adrenal gland: 1546.1 testis: 2.7 IDH1 ENSG00000138413 Isocitrate dehydrogenase 1 (NADP+), soluble 2 208236227-208266074 Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB033218, HPA035248, HPA057936, CAB062556 Supportive Uncertain Nucleus, Cytoplasm Expressed in all adrenal gland: 189.1 IDH2 ENSG00000182054 Isocitrate dehydrogenase 2 (NADP+), mitochondrial 15 90083045-90102504 Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Enzymes, Mitochondrial proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA007831 Supportive Supportive Mitochondria Expressed in all skeletal muscle: 346.7 IDH3A ENSG00000166411 Isocitrate dehydrogenase 3 (NAD+) alpha 15 78131498-78171949 Citric acid cycle related proteins, Enzymes, Mitochondrial proteins, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041465, HPA062971 Supportive Supportive Mitochondria Expressed in all heart muscle: 33.6 IDH3B RP46 ENSG00000101365 Isocitrate dehydrogenase 3 (NAD+) beta 20 2658395-2664219 Citric acid cycle related proteins, Disease related genes, Enzymes, Mitochondrial proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA049387, HPA054180 Supportive Supportive Mitochondria Expressed in all heart muscle: 72.4 IDH3G ENSG00000067829 Isocitrate dehydrogenase 3 (NAD+) gamma X 153785766-153794523 Citric acid cycle related proteins, Enzymes, Mitochondrial proteins, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000425, HPA002017 Supportive Supportive Mitochondria Expressed in all fallopian tube: 43.3 IDO1 IDO, INDO ENSG00000131203 Indoleamine 2,3-dioxygenase 1 8 39902275-39928444 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023072, HPA023149, HPA027772 Supportive Tissue enhanced 0 lymph node: 44.3;placenta: 67.0 appendix: 33.6 IL4I1 FIG1 ENSG00000104951 Interleukin 4 induced 1 19 49889654-49929539 Enzymes, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA045598 Supportive Tissue enhanced 0 appendix: 14.4;testis: 17.9 lymph node: 6.8 IVD ACAD2 ENSG00000128928 Isovaleryl-CoA dehydrogenase 15 40405795-40435947 Disease related genes, Enzymes, Mitochondrial proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041391, HPA044250 Supportive Supportive Mitochondria, Nucleus but not nucleoli Expressed in all thyroid gland: 90.0 IYD C6orf71, DEHAL1, dJ422F24.1 ENSG00000009765 Iodotyrosine deiodinase 6 150368892-150405969 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA059627 Supportive Tissue enriched 24 thyroid gland: 451.1 kidney: 19.1 KDM2A CXXC8, DKFZP434M1735, FBL11, FBL7, FBXL11, FLJ00115, JHDM1A, KIAA1004, LILINA ENSG00000173120 Lysine (K)-specific demethylase 2A 11 67119269-67258087 Enzymes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB012272, HPA042975, HPA044251 Supportive Supportive Nucleus, Nucleoli Expressed in all testis: 35.8 LDHB ENSG00000111716 Lactate dehydrogenase B 12 21635342-21757857 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004641, HPA019007 Supportive Supportive Cytoplasm Expressed in all heart muscle: 1039.2 LDHC CT32 ENSG00000166796 Lactate dehydrogenase C 11 18412307-18452058 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA045442 Supportive Tissue enriched 358 testis: 214.6 fallopian tube: 0.5 LEPRE1 GROS1, LEPRECAN, MGC117314, P3H1 ENSG00000117385 Leucine proline-enriched proteoglycan (leprecan) 1 1 42746335-42767084 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA012113, HPA016980 Supportive Uncertain Vesicles, Nucleoli Expressed in all placenta: 29.1 LEPREL1 FLJ10718, MLAT4, P3H2 ENSG00000090530 Leprecan-like 1 3 189956728-190122437 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA007890, HPA013355 Supportive Mixed prostate: 38.9 LPO SPO ENSG00000167419 Lactoperoxidase 17 58218548-58268518 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028688 Supportive Tissue enriched 552 salivary gland: 426.4 testis: 0.7 MAOA ENSG00000189221 Monoamine oxidase A X 43654907-43746824 Disease related genes, Enzymes, FDA approved drug targets, Mitochondrial proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB009437, HPA054807, HPA059299 Supportive Supportive Mitochondria Mixed small intestine: 178.7 MAOB ENSG00000069535 Monoamine oxidase B X 43766611-43882447 Enzymes, FDA approved drug targets, Mitochondrial proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002328, CAB037200 Supportive Uncertain Nucleoli, Mitochondria Mixed ovary: 130.8 MDH1 ENSG00000014641 Malate dehydrogenase 1, NAD (soluble) 2 63588609-63607197 Cancer-related genes, Citric acid cycle related proteins, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA027296, CAB047333, HPA054276 Supportive Supportive Cytoplasm, Centrosome Expressed in all heart muscle: 622.8 MDH2 ENSG00000146701 Malate dehydrogenase 2, NAD (mitochondrial) 7 76048051-76067508 Citric acid cycle related proteins, Enzymes, Mitochondrial proteins, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019714, HPA019716, HPA019848, HPA026720 Supportive Supportive Mitochondria Expressed in all skeletal muscle: 186.7 ME2 ENSG00000082212 Malic enzyme 2, NAD(+)-dependent, mitochondrial 18 50879049-50954257 Enzymes, Mitochondrial proteins, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008247, HPA008880 Supportive Supportive Mitochondria, Vesicles Expressed in all duodenum: 36.3 MECR CGI-63, FASN2B, NRBF1 ENSG00000116353 Mitochondrial trans-2-enoyl-CoA reductase 1 29192873-29230942 Enzymes, Mitochondrial proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA022018, HPA022030, HPA028740 Supportive Supportive Mitochondria Expressed in all skeletal muscle: 11.7 MIOX ALDRL6 ENSG00000100253 Myo-inositol oxygenase 22 50486784-50490648 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039451, HPA039562 Supportive Uncertain Nucleus but not nucleoli, Cytoplasm Tissue enriched 103 kidney: 802.9 thyroid gland: 7.7 MPO ENSG00000005381 Myeloperoxidase 17 58269856-58280935 Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB000059, HPA021147, HPA061464 Supportive Tissue enriched 273 bone marrow: 2067.0 salivary gland: 7.5 MT-CO1 COI, COX1, MTCO1 ENSG00000198804 Mitochondrially encoded cytochrome c oxidase I MT 5904-7445 Disease related genes, Enzymes, Mitochondrial proteins, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB016241, HPA069328 Supportive Supportive Mitochondria Expressed in all heart muscle: 59869.8 MT-ND3 MTND3, NAD3, ND3 ENSG00000198840 Mitochondrially encoded NADH dehydrogenase 3 MT 10059-10404 Disease related genes, Enzymes, Mitochondrial proteins, Potential drug targets, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA063296 Supportive Uncertain Cytoplasm Expressed in all heart muscle: 39294.6 MTHFD2 ENSG00000065911 Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase 2 74198562-74217565 Enzymes, Mitochondrial proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB003684, HPA049657 Supportive Uncertain Expressed in all appendix: 29.0 MTRR cblE ENSG00000124275 5-methyltetrahydrofolate-homocysteine methyltransferase reductase 5 7851186-7906025 Disease related genes, Enzymes, Mitochondrial proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA038113 Supportive Uncertain Nucleus but not nucleoli, Cytoplasm, Cytoskeleton (Intermediate filaments) Mixed kidney: 11.9 NDUFS2 CI-49 ENSG00000158864 NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase) 1 161197104-161214395 Disease related genes, Enzymes, Mitochondrial proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA055140, HPA061953 Supportive Supportive Mitochondria, Nucleus but not nucleoli Expressed in all heart muscle: 111.6 NDUFV2 CI-24k ENSG00000178127 NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa 18 9102630-9134345 Enzymes, Mitochondrial proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA003404 Supportive Uncertain Expressed in all skeletal muscle: 46.2 NNT ENSG00000112992 Nicotinamide nucleotide transhydrogenase 5 43602692-43707405 Disease related genes, Enzymes, Mitochondrial proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA004829, CAB004975 Supportive Supportive Mitochondria Expressed in all heart muscle: 109.4 NOS3 ECNOS, eNOS ENSG00000164867 Nitric oxide synthase 3 (endothelial cell) 7 150990995-151014588 Cancer-related genes, Cytoskeleton related proteins, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002168 Supportive Tissue enriched 8 spleen: 50.1 adipose tissue: 6.0 NQO1 DHQU, DIA4, DTD, NMOR1, QR1 ENSG00000181019 NAD(P)H dehydrogenase, quinone 1 16 69706996-69726951 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA007308, CAB012421 Supportive Supportive Cytoplasm Tissue enhanced 0 stomach: 425.9 gallbladder: 210.9 NQO2 DHQV, DIA6, NMOR2, QR2 ENSG00000124588 NAD(P)H dehydrogenase, quinone 2 6 2987987-3028869 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021283, HPA021332 Supportive Supportive Nucleus but not nucleoli, Cytoplasm Expressed in all kidney: 133.4 NSDHL H105e3, SDR31E1, XAP104 ENSG00000147383 NAD(P) dependent steroid dehydrogenase-like X 152830967-152869729 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000248, HPA000571 Supportive Supportive Endoplasmic reticulum, Vesicles Expressed in all esophagus: 24.2 NXN FLJ12614, NRX ENSG00000167693 Nucleoredoxin 17 799313-979770 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA022850, HPA023566 Supportive Supportive Cytoplasm, Golgi apparatus Mixed endometrium: 26.7 OGDH E1k ENSG00000105953 Oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) 7 44606572-44709066 Citric acid cycle related proteins, Enzymes, Mitochondrial proteins, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019514, HPA020347 Supportive Supportive Mitochondria Expressed in all heart muscle: 120.2 P4HA1 C-P4Halpha(I), P4HA ENSG00000122884 Prolyl 4-hydroxylase, alpha polypeptide I 10 73007217-73096974 Enzymes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA007599, HPA026593 Supportive Supportive Endoplasmic reticulum, Mitochondria, Vesicles Expressed in all placenta: 56.3 P4HA2 C-P4Halpha(II) ENSG00000072682 Prolyl 4-hydroxylase, alpha polypeptide II 5 132191838-132295315 Enzymes, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA016997, HPA027824, CAB062557 Supportive Supportive Endoplasmic reticulum, Vesicles Expressed in all kidney: 47.3 PAH PH ENSG00000171759 Phenylalanine hydroxylase 12 102836885-102958410 Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028407, HPA031642 Supportive Uncertain Endoplasmic reticulum, Vesicles Group enriched 108 gallbladder: 78.2;kidney: 277.6;liver: 364.3 testis: 2.2 PAM PAL, PHM ENSG00000145730 Peptidylglycine alpha-amidating monooxygenase 5 102753981-103031105 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB026119, HPA042260 Supportive Uncertain Cytoplasm, Golgi apparatus Expressed in all heart muscle: 784.3 PDHB ENSG00000168291 Pyruvate dehydrogenase (lipoamide) beta 3 58427630-58433857 Citric acid cycle related proteins, Disease related genes, Enzymes, Mitochondrial proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB033794, HPA036744, HPA036745 Supportive Supportive Mitochondria, Nucleus but not nucleoli Expressed in all heart muscle: 93.5 PECR HSA250303, SDR29C1, TERP ENSG00000115425 Peroxisomal trans-2-enoyl-CoA reductase 2 215996329-216082955 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021593, HPA022539 Supportive Supportive Vesicles Expressed in all liver: 63.3 PHGDH PDG, PGDH, SERA ENSG00000092621 Phosphoglycerate dehydrogenase 1 119659798-119744215 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB003681, HPA021241, HPA024031, CAB068216 Supportive Supportive Nucleus but not nucleoli, Plasma membrane, Cytoplasm Mixed salivary gland: 76.5 PHYH PAHX, PHYH1, RD ENSG00000107537 Phytanoyl-CoA 2-hydroxylase 10 13277796-13302412 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA007598, HPA011796 Supportive Expressed in all liver: 239.4 PNPO PDXPO ENSG00000108439 Pyridoxamine 5'-phosphate oxidase 17 47941506-47948288 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023204, HPA027776 Supportive Supportive Nucleus but not nucleoli, Cytoplasm Expressed in all liver: 36.5 POR CYPOR, FLJ26468 ENSG00000127948 P450 (cytochrome) oxidoreductase 7 75899200-75986855 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004372, HPA010136 Supportive Uncertain Nucleus but not nucleoli, Vesicles Expressed in all liver: 154.3 PRDX1 NKEFA, PAGA ENSG00000117450 Peroxiredoxin 1 1 45511036-45523047 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004682, HPA007730 Supportive Supportive Mitochondria Expressed in all thyroid gland: 611.9 PRDX3 AOP-1, AOP1, MER5, SP-22 ENSG00000165672 Peroxiredoxin 3 10 119167703-119178833 Enzymes, Mitochondrial proteins, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB008656, HPA041488 Supportive Expressed in all adrenal gland: 295.5 PRDX4 AOE37-2 ENSG00000123131 Peroxiredoxin 4 X 23664262-23686399 Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB008659, CAB027389 Supportive Expressed in all pancreas: 251.9 PRDX5 ACR1, AOEB166, B166, MGC117264, MGC142283, MGC142285, PLP, PMP20, PRDX6, PRXV, SBBI10 ENSG00000126432 Peroxiredoxin 5 11 64318088-64321811 Enzymes, FDA approved drug targets, Mitochondrial proteins, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB008661, HPA037915, HPA037916 Supportive Supportive Cytoplasm, Mitochondria Expressed in all fallopian tube: 377.8 PRDX6 1-Cys, aiPLA2, AOP2, KIAA0106, MGC46173, NSGPx, p29, PRX ENSG00000117592 Peroxiredoxin 6 1 173477266-173488807 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006983, CAB008663 Supportive Supportive Plasma membrane, Cytoplasm, Nucleus but not nucleoli Expressed in all adipose tissue: 240.0 PTGR1 LTB4DH, ZADH3 ENSG00000106853 Prostaglandin reductase 1 9 111549722-111599855 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA036724, HPA036725 Supportive Expressed in all small intestine: 214.7 PTGS1 COX1, PGHS-1, PTGHS ENSG00000095303 Prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) 9 122370530-122395703 Cancer-related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002834, CAB020315 Supportive Supportive Golgi apparatus, Vesicles Tissue enhanced 0 skin: 90.8 esophagus: 63.8 PTGS2 COX2 ENSG00000073756 Prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 1 186671791-186680427 Cancer-related genes, Enzymes, FDA approved drug targets, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB000113, HPA001335 Supportive Tissue enhanced 0 bone marrow: 63.8;urinary bladder: 57.2 gallbladder: 30.9 QDPR DHPR, PKU2, SDR33C1 ENSG00000151552 Quinoid dihydropteridine reductase 4 17460261-17512234 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA058951, HPA065649 Supportive Uncertain Mitochondria Expressed in all cerebral cortex: 104.2 RDH11 ARSDR1, MDT1, SDR7C1 ENSG00000072042 Retinol dehydrogenase 11 (all-trans/9-cis/11-cis) 14 67676801-67695814 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB046011 Supportive Tissue enriched 8 prostate: 523.7 kidney: 65.1 RRM1 ENSG00000167325 Ribonucleotide reductase M1 11 4094707-4138876 Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB022093, HPA057265, HPA064297 Supportive Supportive Cytoplasm Expressed in all tonsil: 39.8 SARDH DMGDHL1, SDH ENSG00000123453 Sarcosine dehydrogenase 9 133663560-133739955 Disease related genes, Enzymes, Mitochondrial proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA057267, HPA058086 Supportive Uncertain Mitochondria Group enriched 7 kidney: 14.6;liver: 38.3;pancreas: 11.2 salivary gland: 2.9 SDHA FP, SDH2, SDHF ENSG00000073578 Succinate dehydrogenase complex, subunit A, flavoprotein (Fp) 5 218241-256700 Citric acid cycle related proteins, Disease related genes, Enzymes, Mitochondrial proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB034929, HPA041981, HPA064582 Supportive Supportive Mitochondria Expressed in all heart muscle: 217.1 SDHB SDH, SDH1 ENSG00000117118 Succinate dehydrogenase complex, subunit B, iron sulfur (Ip) 1 17018722-17054170 Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Enzymes, Mitochondrial proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002868, CAB009822, CAB068233, CAB068234, CAB068235 Supportive Supportive Mitochondria, Nucleus but not nucleoli, Plasma membrane Expressed in all heart muscle: 136.8 SOD1 ALS, ALS1, IPOA ENSG00000142168 Superoxide dismutase 1, soluble 21 31659622-31668931 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001401, CAB008670 Supportive Supportive Nucleus, Cytoplasm, Plasma membrane Expressed in all liver: 629.6 SOD2 ENSG00000112096 Superoxide dismutase 2, mitochondrial 6 159669057-159762529 Cancer-related genes, Disease related genes, Enzymes, Mitochondrial proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001814, CAB002013 Supportive Expressed in all bone marrow: 567.3 SOD3 EC-SOD ENSG00000109610 Superoxide dismutase 3, extracellular 4 24789912-24800842 Enzymes, Plasma proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA042110 Supportive Tissue enhanced 0 adipose tissue: 111.3 prostate: 50.2 SORD ENSG00000140263 Sorbitol dehydrogenase 15 45023104-45077185 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA040260, HPA040621 Supportive Group enriched 7 kidney: 75.1;liver: 172.0;prostate: 164.5;thyroid gland: 203.4 urinary bladder: 23.5 TECR GPSN2, MRT14, SC2, TER ENSG00000099797 Trans-2,3-enoyl-CoA reductase 19 14517085-14565980 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA029780, HPA056488 Supportive Supportive Endoplasmic reticulum Expressed in all esophagus: 135.8 TET1 bA119F7.1, CXXC6, KIAA1676, LCX ENSG00000138336 Tet methylcytosine dioxygenase 1 10 68560656-68694482 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Transcription factors Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB014886, HPA019032, HPA057273 Supportive Supportive Nucleus, Nuclear membrane Mixed placenta: 1.0 TH DYT5b ENSG00000180176 Tyrosine hydroxylase 11 2163929-2171877 Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002522, HPA061003, CAB072340 Supportive Supportive Tissue enriched 70 adrenal gland: 133.5 adipose tissue: 1.9 TPH1 TPH, TPRH ENSG00000129167 Tryptophan hydroxylase 1 11 18017564-18042426 Enzymes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level CAB010767, HPA022483 Supportive Uncertain Cytoplasm Group enriched 9 colon: 6.7;duodenum: 7.3;rectum: 12.7;small intestine: 7.4;stomach: 10.1 prostate: 0.9 TPO TPX ENSG00000115705 Thyroid peroxidase 2 1374223-1543711 Disease related genes, Enzymes, FDA approved drug targets, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level HPA007987, CAB009587 Supportive Uncertain Cytoplasm Tissue enriched 68 thyroid gland: 1821.7 spleen: 26.7 TYR OCA1, OCA1A, OCAIA ENSG00000077498 Tyrosinase 11 89177452-89295759 Disease related genes, Enzymes, FDA approved drug targets, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB000079 Supportive Tissue enriched 186 skin: 18.5 adipose tissue: 0.0 UGDH ENSG00000109814 UDP-glucose 6-dehydrogenase 4 39498755-39528311 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB034444, HPA036656, HPA036657 Supportive Supportive Nucleus Expressed in all colon: 80.3 UQCRFS1 RIP1, RIS1, RISP, UQCR5 ENSG00000169021 Ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 19 29205321-29213541 Enzymes, Mitochondrial proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041863, HPA050339 Supportive Supportive Mitochondria Expressed in all skeletal muscle: 47.0