THE HUMAN PROTEIN ATLAS BLOG
Another PhD student within the Human Protein Atlas has successfully graduated
Arash Zandian defended his PhD-thesis "Array-based autoantibody profiling and epitope mapping" on October 6th where he presented the work he has performed during the last 4 years at SciLifeLab, School of Biotechnology, KTH Royal Institute of Technology. The last decades of technical development and availability of protein and peptide microarrays have enabled large-scale profiling of antibodies and precise determination of their specificities through epitope mapping. In this thesis the aim was to use affinity proteomics tools to profile antibodies, determine their specificities, and discover potential associations of autoantigens to disease by analyzing blood-derived samples with microarray-based methods. Here described with articles in the field of narcolepsy, multiple sclerosis, psychosis and malaria.