NUP62

GENERAL INFORMATION

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Gene name

NUP62

Gene description

Nucleoporin 62kDa

Protein class

Cytoskeleton related proteins
Disease related genes
Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

15
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Expressed in all
GTEx:Tissue enhanced (testis)

Protein evidence

Evidence at protein level

Protein localization

General nuclear membranous expression, additional cytoplasmic expression in several cases.

ANTIBODY RELIABILITY

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Data reliability
description

Pending RNA-based expert annotation.

Data reliability

Supportive based on 2 antibodies.
HPA005435 , CAB020724
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Pancreas

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Expressed in all

Organ

Expression

GTEx dataset
RNA tissue category:  Tissue enhanced (testis)

Organ

Expression



GENE INFORMATION

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Gene name

NUP62 (HGNC Symbol)

Synonyms

DKFZp547L134, FLJ20822, FLJ43869, IBSN, MGC841, p62, SNDI

Description

Nucleoporin 62kDa (HGNC Symbol)

Entrez gene summary

The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins are the main components of the nuclear pore complex in eukaryotic cells. The protein encoded by this gene is a member of the FG-repeat containing nucleoporins and is localized to the nuclear pore central plug. This protein associates with the importin alpha/beta complex which is involved in the import of proteins containing nuclear localization signals. Multiple transcript variants of this gene encode a single protein isoform. [provided by RefSeq, Jul 2008]

Chromosome

19

Cytoband

q13.33

Chromosome location (bp)

49906825 - 49929763

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000213024 (version 78.38)

Entrez gene

23636

UniProt

P37198 (UniProt - Evidence at protein level)

neXtProt

NX_P37198

Antibodypedia

NUP62 antibodies


PROTEIN BROWSER

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ENST00000352066
 
ENST00000413454
 
ENST00000422090
 
ENST00000593652
 
ENST00000594673
 
ENST00000595761
 
ENST00000596217
 
ENST00000596437
 
ENST00000596680
 
ENST00000597029
 
ENST00000597723
 
ENST00000599567
 
ENST00000599788
 
ENST00000600645
 
ENST00000600935
 
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PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

NUP62-001 ENSP00000305503
ENST00000352066
P37198
Show all »
Show » Show » 522 53.3 No 0
NUP62-002 ENSP00000473192
ENST00000597029
P37198
Show all »
Show » Show » 522 53.3 No 0
NUP62-003 ENSP00000471191
ENST00000596217
P37198
Show all »
Show » Show » 522 53.3 No 0
NUP62-004 ENSP00000407331
ENST00000422090
P37198
Show all »
Show » Show » 522 53.3 No 0
NUP62-005 ENSP00000469283
ENST00000597723
M0QXN5
Show all »
Show » Show » 446 45.6 No 0
NUP62-008 ENSP00000472081
ENST00000599567
M0R1S1
Show all »
Show » Show » 100 9.6 No 0
NUP62-013 ENSP00000472918
ENST00000593652
M0R302
Show all »
Show » Show » 138 13.2 No 0
NUP62-014 ENSP00000470157
ENST00000594673
M0QYY0
Show all »
Show » Show » 36 3.5 No 0
NUP62-015 ENSP00000468884
ENST00000599788
M0QX10
Show all »
Show » 24 2.3 No 0
NUP62-016 ENSP00000468839
ENST00000600935
M0QX10
Show all »
Show » 23 2.2 No 0
NUP62-017 ENSP00000471133
ENST00000596680
M0R0B7
Show all »
Show » 19 1.8 No 0
NUP62-020 ENSP00000468842
ENST00000596437
M0QX13
Show all »
Show » Show » 75 7.3 No 0
NUP62-023 ENSP00000468930
ENST00000595761
M0QX64
Show all »
Show » Show » 134 12.8 No 0
NUP62-024 ENSP00000470624
ENST00000600645
M0QZL5
Show all »
Show » Show » 99 9.5 No 0
NUP62-201 ENSP00000387991
ENST00000413454
M0R302
Show all »
Show » Show » 193 18.4 No 0