RUSC2

GENERAL INFORMATION

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Gene name

RUSC2

Gene description

RUN and SH3 domain containing 2

Protein class

Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

2
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

Moderate nuclear and cytoplasmic immunoreactivity was observed in most normal cells. Strongly stained nuclei were observed in parathyroid gland. Spleen and most squamous epithelial cells were weakly stained.

ANTIBODY RELIABILITY

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Data reliability
description

Pending RNA-based expert annotation.

Data reliability

Uncertain based on 1 antibody.
HPA021297
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Expressed in all

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

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Gene name

RUSC2 (HGNC Symbol)

Synonyms

KIAA0375

Description

RUN and SH3 domain containing 2 (HGNC Symbol)

Entrez gene summary

This gene encodes a RUN and SH3 domain containing protein that interacts with Rab1b and Rab1-binding protein GM130. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jun 2012]

Chromosome

9

Cytoband

p13.3

Chromosome location (bp)

35490127 - 35561898

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000198853 (version 78.38)

Entrez gene

9853

UniProt

Q8N2Y8 (UniProt - Evidence at protein level)

neXtProt

NX_Q8N2Y8

Antibodypedia

RUSC2 antibodies


PROTEIN BROWSER

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ENST00000361226
 
ENST00000455600
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

RUSC2-001 ENSP00000355177
ENST00000361226
Q8N2Y8
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Show » Show » 1516 161.2 No 0
RUSC2-201 ENSP00000393922
ENST00000455600
Q8N2Y8
Show all »
Show » Show » 1516 161.2 No 0