PTPN1

CANCER ATLAS

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Gene description

Protein tyrosine phosphatase, non-receptor type 1

Protein class

Enzymes, Predicted membrane proteins

Protein evidence

Evidence at protein level
 
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer

STAINING SUMMARY

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HPA012542
 
CAB009329
 
 
CAB015217
 

Tissue

Cancer staining

Protein
expression of
normal tissue

Breast cancer
 
Carcinoid
 
Cervical cancer
 
 
Colorectal cancer
 
 
Endometrial cancer
 
 
Glioma
 
Head and neck cancer
 
 
Liver cancer
 
 
Lung cancer
 
 
Lymphoma
 
 
 

Tissue

Cancer staining

Protein
expression of
normal tissue

Melanoma
 
Ovarian cancer
 
Pancreatic cancer
 
Prostate cancer
 
Renal cancer
 
Skin cancer
 
Stomach cancer
 
 
Testis cancer
 
Thyroid cancer
 
Urothelial cancer
 
 

Staining summary

Malignant lymphomas exhibited strong cytoplasmic staining in most cases whereas malignant melanomas, endometrial and cervical malignancies exhibited several strongly stained cases. Remaining tumors displayed occasional distinctly stained cases but most malignant cells were negative.
 

Level of antibody staining/expression





High
Medium
Low
Not detected