CNR2

GENE INFORMATION

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Gene name

CNR2 (HGNC Symbol)

Synonyms

CB2

Description

Cannabinoid receptor 2 (macrophage) (HGNC Symbol)

Entrez gene summary

The cannabinoid delta-9-tetrahydrocannabinol is the principal psychoactive ingredient of marijuana. The proteins encoded by this gene and the cannabinoid receptor 1 (brain) (CNR1) gene have the characteristics of a guanine nucleotide-binding protein (G-protein)-coupled receptor for cannabinoids. They inhibit adenylate cyclase activity in a dose-dependent, stereoselective, and pertussis toxin-sensitive manner. These proteins have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. The cannabinoid receptors are members of family 1 of the G-protein-coupled receptors. [provided by RefSeq, Jul 2008]

Chromosome

1

Cytoband

p36.11

Chromosome location (bp)

23870526 - 23913362

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000188822 (version 78.38)

Entrez gene

1269

UniProt

P34972 (UniProt - Evidence at protein level)

neXtProt

NX_P34972

Antibodypedia

CNR2 antibodies
 

PROTEIN VIEW

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CNR2-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CNR2-001 ENSP00000363596
ENST00000374472
P34972
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