SECISBP2

GENE INFORMATION

? »

Gene name

SECISBP2

Synonyms

Description

SECIS binding protein 2 (HGNC Symbol)

Entrez gene summary

The incorporation of selenocysteine into a protein requires the concerted action of an mRNA element called a sec insertion sequence (SECIS), a selenocysteine-specific translation elongation factor and a SECIS binding protein. With these elements in place, a UGA codon can be decoded as selenocysteine. The gene described in this record encodes a nuclear protein that functions as a SECIS binding protein. Mutations in this gene have been associated with a reduction in activity of a specific thyroxine deiodinase, a selenocysteine-containing enzyme, and abnormal thyroid hormone metabolism. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]

Chromosome

9

Cytoband

q22.2

Chromosome location (bp)

89318506 - 89359662

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000187742 (version 78.38)

Entrez gene

79048

UniProt

Q96T21 (UniProt - Evidence at protein level)

neXtProt

NX_Q96T21

Antibodypedia

SECISBP2 antibodies
 

PROTEIN VIEW

? »
 
 
 
SECISBP2-001
 
SECISBP2-002
 
SECISBP2-003
 
SECISBP2-004
 
SECISBP2-201
 
 
 
 
 

PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SECISBP2-001 ENSP00000364965
ENST00000375807
Q96T21
Show all »
Show » Show » 854 95.5 No 0
SECISBP2-002 ENSP00000414288
ENST00000425851
Q5HYY5
Show all »
Show » 275 30.5 No 0
SECISBP2-003 ENSP00000411573
ENST00000440898
Q4V370
Show all »
Show » 60 7.2 No 0
SECISBP2-004 ENSP00000364959
ENST00000339901
Q96T21
Show all »
Show » Show » 781 87.4 Yes 0
SECISBP2-201 ENSP00000436650
ENST00000534113
Q96T21
Show all »
Show » Show » 786 88 No 0