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GENERAL INFORMATION
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Protein class
Protein class the gene product belongs to according to selected gene lists. List of protein classes.
Predicted localization
Protein localization predicted from several bioinformatic algorithms. More info...
Number of transcripts
Number of protein-coding transcribed from this gene as defined by Ensembl.
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Gene name |
RHD |
Gene description |
Rh blood group, D antigen |
Protein class |
Blood group antigen proteins
CD markers
Predicted membrane proteins
Transporters |
Predicted localization |
Membrane |
Number of transcripts |
9 |
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HUMAN PROTEIN ATLAS INFORMATION
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RNA tissue category
The RNA tissue category is based on mRNA expression levels in 32 different tissues ( RNA assay description).
The categories include: tissue enriched, group enriched, tissue enhanced, expressed in all, not detected, and mixed.
RNA tissue category is calculated separately both for internally generated Human Protein Atlas (HPA) RNA-seq data, as
well as RNA-seq data from the Genotype-Tissue Expression ( GTEx) consortium.
Protein evidence
Protein evidence scores are generated from several independent sources
and are classified as evidence at i) protein level, ii) transcript level, iii) no evidence or iv) not available.
Protein localization
A summary of the overall protein expression pattern across the analyzed tissues. The summary is based on knowledge-based
annotation ( Annotation description). For genes pending
knowledge-based annotation, the protein localization refers to the antibody staining pattern.
"RNA-based expert annotation gave inconconclusive results" is shown for genes analyzed with a knowledge-based approach where
available RNA-seq and gene/protein characterization data has been evaluated as not sufficient in combination with
immunohistochemistry-data to yield a reliable estimation of the protein expression profile.
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RNA tissue category |
| HPA: | Tissue enriched (bone marrow) |
| GTEx: | Tissue enhanced (salivary gland) |
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Protein evidence |
Evidence at protein level |
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ANTIBODY RELIABILITY
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Data reliability description
Standardized explanatory sentences with additional information required for full understanding of the
knowledge-based expression profile. Currently, not all genes have been analyzed by knowledge-based
annotation, indicated by "Pending RNA-based expert annotation", when applicable.
Data reliability
Data reliability score ( score description), divided into supportive (premium)
or uncertain (not premium), is based on consistency between the staining pattern of one antibody or several
antibodies with RNA-seq data and available gene/protein characterization data.
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Data reliability |
Pending normal tissue annotation. |
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PROTEIN EXPRESSION OVERVIEW
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Protein expression data is shown for each of the 44 tissues. Color-coding is based on 13 tissue groups, each consisting
of tissues with common functional features. Mouse-over function shows protein score for analyzed cell types found in a
selected tissue. To access image data click on tissue name or bar. Annotation of protein expression is described in
detail in Assays & annotation.
For genes with available protein data for which a knowledge-based annotation could not be performed, no protein
expression data is displayed in the protein expression data overview, however, all immunohistochemical images are
still available and the annotation data can be found under Primary data.
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Pending normal tissue annotation.
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GENE INFORMATION
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Gene information from Ensembl and Entrez, as well as links to available gene identifiers are displayed here. Information was retrieved from Ensembl if not indicated otherwise.
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Gene name |
RHD (HGNC Symbol) |
Synonyms |
CD240D, DIIIc, RH, Rh30a, Rh4, RhII, RhPI |
Description |
Rh blood group, D antigen (HGNC Symbol) |
Entrez gene summary |
The Rh blood group system is the second most clinically significant of the blood groups, second only to ABO. It is also the most polymorphic of the blood groups, with variations due to deletions, gene conversions, and missense mutations. The Rh blood group includes this gene, which encodes the RhD protein, and a second gene that encodes both the RhC and RhE antigens on a single polypeptide. The two genes, and a third unrelated gene, are found in a cluster on chromosome 1. The classification of Rh-positive and Rh-negative individuals is determined by the presence or absence of the highly immunogenic RhD protein on the surface of erythrocytes. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
Chromosome |
1 |
Cytoband |
p36.11 |
Chromosome location (bp) |
25272393 - 25330445 |
Protein evidence |
Evidence at protein level (all genes) |
Ensembl |
ENSG00000187010 (version 78.38) |
Entrez gene |
6007 |
UniProt |
Q02161 (UniProt - Evidence at protein level) |
neXtProt |
NX_Q02161 |
Antibodypedia |
RHD antibodies |
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PROTEIN BROWSER
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The protein browser displays the antigen location on the target protein(s) and the features of the target protein. The
tabs at the top of the protein view section can be used to switch between the different splice variants to which
an antigen has been mapped.
At the top of the view, the position of the antigen (identified by the corresponding HPA identifier) is shown as a green
bar. A yellow triangle on the bar indicates a <100% sequence identity to the protein target.
Under the antigens, the maximum percent sequence identity of the protein to all other proteins from other human genes is
displayed, using a sliding window of 10 aa residues (HsID 10) or 50 aa residues
(HsID 50) ( read more).
If a signal peptide is predicted by a majority of the signal peptide predictors SPOCTOPUS,
SignalP 4.0, and
Phobius (turquoise)
and/or transmembrane regions (orange) are predicted by MDM, these are displayed.
Low complexity regions are shown in yellow
and InterPro regions in green. Common (purple) and
unique (grey) regions between different splice variants of the gene are also displayed
( read more), and at the
bottom of the protein view is the protein scale.
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PROTEIN INFORMATION
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The protein information section displays alternative protein-coding transcripts (splice variants) encoded by this
gene according to the Ensembl database.
The ENSP identifier links to the Ensembl website protein summary, while the ENST identifier links to the Ensembl website transcript summary
for the selected splice variant. The data in the UniProt column can be expanded to show links to all matching
UniProt identifiers for this protein.
The protein classes assigned to this protein are shown if expanding the data in the
protein class column. Parent protein classes are in bold font and subclasses are listed under the parent class.
The Gene Ontology terms assigned to this protein are
listed if expanding the Gene ontology column.
The length of the protein (amino acid residues according to Ensembl), molecular mass (kDalton), predicted signal peptide (according to a
majority of the signal peptide predictors SPOCTOPUS,
SignalP 4.0 and
Phobius) and the number of predicted transmembrane region(s)
(according to MDM) are also reported.
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Splice variant |
Ensembl |
UniProt |
Protein class |
Gene ontology |
Length
(aa) |
Molecular mass
(kDa) |
Signal peptide
(predicted) |
Transmembrane regions
(predicted)
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| RHD-001 |
ENSP00000331871
ENST00000328664
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Q02161
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« Hide
Q02161 [Direct mapping]Blood group Rh(D) polypeptide I2HA01 [Target identity:82%; Query identity:100%]Rhesus blood group D antigen {ECO:0000313|EMBL:CCH63384.1} B4F4S0 [Target identity:76%; Query identity:100%]Rhesus blood group, D antigen {ECO:0000313|EMBL:CAQ53124.1} E7BAS5 [Target identity:73%; Query identity:100%]Rhesus blood group, D antigen {ECO:0000313|EMBL:CBY78080.1} B4F4S7 [Target identity:64%; Query identity:100%]Rhesus blood group, D antigen {ECO:0000313|EMBL:CAQ53131.1} I2HA00 [Target identity:61%; Query identity:100%]Rhesus blood group D antigen {ECO:0000313|EMBL:CCH63383.1} B2ZGQ0 [Target identity:30%; Query identity:100%]Truncated Rhesus blood group D antigen {ECO:0000313|EMBL:ACD43642.1} Q9UDZ3 [Target identity:29%; Query identity:100%]RHD protein {ECO:0000313|EMBL:CAB10170.1} D8MJ84 [Target identity:14%; Query identity:100%]Rh blood group D antigen {ECO:0000313|EMBL:CBS91667.1} P78522 [Target identity:14%; Query identity:100%]Rh blood group C antigen {ECO:0000313|EMBL:AAB39601.1}; Rh blood group D antigen {ECO:0000313|EMBL:AFH77606.1}; Rh blood group, CcEe antigens {ECO:0000313|EMBL:CAS02275.1}; Rh blood group, D antigen {ECO:0000313|EMBL:CBB12662.1} Q49IM6 [Target identity:13%; Query identity:100%]Rh blood group D antigen {ECO:0000313|EMBL:AFM38801.1}; Rh blood group, D antigen {ECO:0000313|EMBL:CBM95511.1}; Rhesus blood group D antigen {ECO:0000313|EMBL:AAX63192.1} Q6A1H1 [Target identity:12%; Query identity:100%]Rhesus blood group D antigen {ECO:0000313|EMBL:CAH04922.2} I0CKG6 [Target identity:11%; Query identity:100%]Rh blood group D antigen {ECO:0000313|EMBL:AFH77613.1} A0PFK1 [Target identity:11%; Query identity:100%]Rhesus blood group C antigen {ECO:0000313|EMBL:CAL69447.1} A9P3T3 [Target identity:11%; Query identity:100%]Rh blood group D antigen {ECO:0000313|EMBL:AGC26025.1}; Rh blood group RHD {ECO:0000313|EMBL:AEF57639.1}; RhD antigen {ECO:0000313|EMBL:AEL12218.1}; Rhesus blood group D antigen {ECO:0000313|EMBL:ABO28976.1} D2CRH1 [Target identity:11%; Query identity:100%]Rhesus blood group D antigen {ECO:0000313|EMBL:ACF09154.1} Q9UEC7 [Target identity:11%; Query identity:100%]Rh blood group D antigen {ECO:0000313|EMBL:AGC26023.1}; RhC protein {ECO:0000313|EMBL:BAA36694.1}; RhD {ECO:0000313|EMBL:AAN86717.1}; Rhesus blood group D antigen {ECO:0000313|EMBL:AEP84116.1} Q5NDM5 [Target identity:10%; Query identity:100%]Rhesus blood group C antigen {ECO:0000313|EMBL:CAI30431.1} A7Y8S3 [Target identity:10%; Query identity:100%]Rh blood group D antigen {ECO:0000313|EMBL:AFM38089.1}; Rhesus blood group D antigen {ECO:0000313|EMBL:ABJ90065.1} G0TQY3 [Target identity:8%; Query identity:100%]Rhesus blood group D antigen {ECO:0000313|EMBL:CCC42282.1} D8MJ86 [Target identity:8%; Query identity:100%]Truncated Rh blood group D antigen {ECO:0000313|EMBL:CBS91669.1} T2DL33 [Target identity:7%; Query identity:100%]RHD antigen {ECO:0000313|EMBL:AGV53068.1} W6AWB5 [Target identity:6%; Query identity:100%]Rh blood group D antigen {ECO:0000313|EMBL:AHI63008.1} Q8NFY2 [Target identity:5%; Query identity:100%]Rh blood group D antigen {ECO:0000313|EMBL:AHI63000.1}; Rh blood group, D antigen {ECO:0000313|EMBL:CBM95509.1}; RhD variant {ECO:0000313|EMBL:AHJ11198.1}; Rhesus blood group D antigen {ECO:0000313|EMBL:AAM46621.1}
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CD markers
Blood group antigen proteins
Transporters
Transporter channels and pores
Predicted membrane proteins
Prediction method-based
Membrane proteins predicted by MDM
MEMSAT3 predicted membrane proteins
MEMSAT-SVM predicted membrane proteins
Phobius predicted membrane proteins
SCAMPI predicted membrane proteins
SPOCTOPUS predicted membrane proteins
THUMBUP predicted membrane proteins
TMHMM predicted membrane proteins
# TM segments-based
>9TM proteins predicted by MDM
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Show »
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417 |
45.2 |
No |
>9 |
| RHD-004 |
ENSP00000413849
ENST00000454452
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Q02161
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Q02161 [Direct mapping]Blood group Rh(D) polypeptide Q5XLT3 [Target identity:100%; Query identity:100%]RHD protein {ECO:0000313|EMBL:AAI39923.1}; Rhesus blood group D antigen isoform 1 {ECO:0000313|EMBL:AAU93635.1} E7BAS5 [Target identity:95%; Query identity:100%]Rhesus blood group, D antigen {ECO:0000313|EMBL:CBY78080.1} B4F4S7 [Target identity:83%; Query identity:100%]Rhesus blood group, D antigen {ECO:0000313|EMBL:CAQ53131.1} I2HA00 [Target identity:79%; Query identity:100%]Rhesus blood group D antigen {ECO:0000313|EMBL:CCH63383.1} B2ZGQ0 [Target identity:39%; Query identity:100%]Truncated Rhesus blood group D antigen {ECO:0000313|EMBL:ACD43642.1} D8MJ84 [Target identity:19%; Query identity:100%]Rh blood group D antigen {ECO:0000313|EMBL:CBS91667.1} P78522 [Target identity:19%; Query identity:100%]Rh blood group C antigen {ECO:0000313|EMBL:AAB39601.1}; Rh blood group D antigen {ECO:0000313|EMBL:AFH77606.1}; Rh blood group, CcEe antigens {ECO:0000313|EMBL:CAS02275.1}; Rh blood group, D antigen {ECO:0000313|EMBL:CBB12662.1} Q49IM6 [Target identity:17%; Query identity:100%]Rh blood group D antigen {ECO:0000313|EMBL:AFM38801.1}; Rh blood group, D antigen {ECO:0000313|EMBL:CBM95511.1}; Rhesus blood group D antigen {ECO:0000313|EMBL:AAX63192.1} Q6A1H1 [Target identity:16%; Query identity:100%]Rhesus blood group D antigen {ECO:0000313|EMBL:CAH04922.2} A9P3T3 [Target identity:15%; Query identity:100%]Rh blood group D antigen {ECO:0000313|EMBL:AGC26025.1}; Rh blood group RHD {ECO:0000313|EMBL:AEF57639.1}; RhD antigen {ECO:0000313|EMBL:AEL12218.1}; Rhesus blood group D antigen {ECO:0000313|EMBL:ABO28976.1} Q9UEC7 [Target identity:15%; Query identity:100%]Rh blood group D antigen {ECO:0000313|EMBL:AGC26023.1}; RhC protein {ECO:0000313|EMBL:BAA36694.1}; RhD {ECO:0000313|EMBL:AAN86717.1}; Rhesus blood group D antigen {ECO:0000313|EMBL:AEP84116.1} D2CRH1 [Target identity:15%; Query identity:100%]Rhesus blood group D antigen {ECO:0000313|EMBL:ACF09154.1} I0CKG6 [Target identity:14%; Query identity:100%]Rh blood group D antigen {ECO:0000313|EMBL:AFH77613.1} Q5NDM5 [Target identity:14%; Query identity:100%]Rhesus blood group C antigen {ECO:0000313|EMBL:CAI30431.1} A0PFK1 [Target identity:14%; Query identity:100%]Rhesus blood group C antigen {ECO:0000313|EMBL:CAL69447.1} G0TQY3 [Target identity:11%; Query identity:100%]Rhesus blood group D antigen {ECO:0000313|EMBL:CCC42282.1} D8MJ86 [Target identity:11%; Query identity:100%]Truncated Rh blood group D antigen {ECO:0000313|EMBL:CBS91669.1}
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CD markers
Blood group antigen proteins
Transporters
Transporter channels and pores
Predicted membrane proteins
Prediction method-based
Membrane proteins predicted by MDM
MEMSAT3 predicted membrane proteins
MEMSAT-SVM predicted membrane proteins
Phobius predicted membrane proteins
SCAMPI predicted membrane proteins
SPOCTOPUS predicted membrane proteins
THUMBUP predicted membrane proteins
TMHMM predicted membrane proteins
# TM segments-based
9TM proteins predicted by MDM
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321 |
34.8 |
No |
9 |
| RHD-005 |
ENSP00000396420
ENST00000417538
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Q02161
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Q02161 [Direct mapping]Blood group Rh(D) polypeptide E7BAS5 [Target identity:81%; Query identity:100%]Rhesus blood group, D antigen {ECO:0000313|EMBL:CBY78080.1} B4F4S7 [Target identity:70%; Query identity:100%]Rhesus blood group, D antigen {ECO:0000313|EMBL:CAQ53131.1} I2HA00 [Target identity:67%; Query identity:100%]Rhesus blood group D antigen {ECO:0000313|EMBL:CCH63383.1} B2ZGQ0 [Target identity:33%; Query identity:100%]Truncated Rhesus blood group D antigen {ECO:0000313|EMBL:ACD43642.1} D8MJ84 [Target identity:16%; Query identity:100%]Rh blood group D antigen {ECO:0000313|EMBL:CBS91667.1} P78522 [Target identity:16%; Query identity:100%]Rh blood group C antigen {ECO:0000313|EMBL:AAB39601.1}; Rh blood group D antigen {ECO:0000313|EMBL:AFH77606.1}; Rh blood group, CcEe antigens {ECO:0000313|EMBL:CAS02275.1}; Rh blood group, D antigen {ECO:0000313|EMBL:CBB12662.1} Q6A1H1 [Target identity:14%; Query identity:100%]Rhesus blood group D antigen {ECO:0000313|EMBL:CAH04922.2} Q49IM6 [Target identity:14%; Query identity:100%]Rh blood group D antigen {ECO:0000313|EMBL:AFM38801.1}; Rh blood group, D antigen {ECO:0000313|EMBL:CBM95511.1}; Rhesus blood group D antigen {ECO:0000313|EMBL:AAX63192.1} A9P3T3 [Target identity:13%; Query identity:100%]Rh blood group D antigen {ECO:0000313|EMBL:AGC26025.1}; Rh blood group RHD {ECO:0000313|EMBL:AEF57639.1}; RhD antigen {ECO:0000313|EMBL:AEL12218.1}; Rhesus blood group D antigen {ECO:0000313|EMBL:ABO28976.1} I0CKG6 [Target identity:12%; Query identity:100%]Rh blood group D antigen {ECO:0000313|EMBL:AFH77613.1} D2CRH1 [Target identity:12%; Query identity:100%]Rhesus blood group D antigen {ECO:0000313|EMBL:ACF09154.1} Q9UEC7 [Target identity:12%; Query identity:100%]Rh blood group D antigen {ECO:0000313|EMBL:AGC26023.1}; RhC protein {ECO:0000313|EMBL:BAA36694.1}; RhD {ECO:0000313|EMBL:AAN86717.1}; Rhesus blood group D antigen {ECO:0000313|EMBL:AEP84116.1} A0PFK1 [Target identity:12%; Query identity:100%]Rhesus blood group C antigen {ECO:0000313|EMBL:CAL69447.1} Q5NDM5 [Target identity:11%; Query identity:100%]Rhesus blood group C antigen {ECO:0000313|EMBL:CAI30431.1} G0TQY3 [Target identity:9%; Query identity:100%]Rhesus blood group D antigen {ECO:0000313|EMBL:CCC42282.1} D8MJ86 [Target identity:9%; Query identity:100%]Truncated Rh blood group D antigen {ECO:0000313|EMBL:CBS91669.1} J7GUD8 [Target identity:6%; Query identity:100%]Rh blood group D antigen {ECO:0000313|EMBL:AFP86357.1}
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CD markers
Blood group antigen proteins
Transporters
Transporter channels and pores
Predicted membrane proteins
Prediction method-based
Membrane proteins predicted by MDM
MEMSAT3 predicted membrane proteins
MEMSAT-SVM predicted membrane proteins
Phobius predicted membrane proteins
SCAMPI predicted membrane proteins
SPOCTOPUS predicted membrane proteins
THUMBUP predicted membrane proteins
TMHMM predicted membrane proteins
# TM segments-based
9TM proteins predicted by MDM
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378 |
41.7 |
No |
9 |
| RHD-006 |
ENSP00000350150
ENST00000357542
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Q02161
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Q02161 [Direct mapping]Blood group Rh(D) polypeptide I2HA01 [Target identity:86%; Query identity:100%]Rhesus blood group D antigen {ECO:0000313|EMBL:CCH63384.1} B4F4S0 [Target identity:80%; Query identity:100%]Rhesus blood group, D antigen {ECO:0000313|EMBL:CAQ53124.1} E7BAS5 [Target identity:77%; Query identity:100%]Rhesus blood group, D antigen {ECO:0000313|EMBL:CBY78080.1} B4F4S7 [Target identity:67%; Query identity:100%]Rhesus blood group, D antigen {ECO:0000313|EMBL:CAQ53131.1} I2HA00 [Target identity:64%; Query identity:100%]Rhesus blood group D antigen {ECO:0000313|EMBL:CCH63383.1} B2ZGQ0 [Target identity:32%; Query identity:100%]Truncated Rhesus blood group D antigen {ECO:0000313|EMBL:ACD43642.1} Q9UDZ3 [Target identity:31%; Query identity:100%]RHD protein {ECO:0000313|EMBL:CAB10170.1} D8MJ84 [Target identity:15%; Query identity:100%]Rh blood group D antigen {ECO:0000313|EMBL:CBS91667.1} P78522 [Target identity:15%; Query identity:100%]Rh blood group C antigen {ECO:0000313|EMBL:AAB39601.1}; Rh blood group D antigen {ECO:0000313|EMBL:AFH77606.1}; Rh blood group, CcEe antigens {ECO:0000313|EMBL:CAS02275.1}; Rh blood group, D antigen {ECO:0000313|EMBL:CBB12662.1} Q6A1H1 [Target identity:13%; Query identity:100%]Rhesus blood group D antigen {ECO:0000313|EMBL:CAH04922.2} Q49IM6 [Target identity:13%; Query identity:100%]Rh blood group D antigen {ECO:0000313|EMBL:AFM38801.1}; Rh blood group, D antigen {ECO:0000313|EMBL:CBM95511.1}; Rhesus blood group D antigen {ECO:0000313|EMBL:AAX63192.1} A9P3T3 [Target identity:12%; Query identity:100%]Rh blood group D antigen {ECO:0000313|EMBL:AGC26025.1}; Rh blood group RHD {ECO:0000313|EMBL:AEF57639.1}; RhD antigen {ECO:0000313|EMBL:AEL12218.1}; Rhesus blood group D antigen {ECO:0000313|EMBL:ABO28976.1} D2CRH1 [Target identity:12%; Query identity:100%]Rhesus blood group D antigen {ECO:0000313|EMBL:ACF09154.1} Q9UEC7 [Target identity:12%; Query identity:100%]Rh blood group D antigen {ECO:0000313|EMBL:AGC26023.1}; RhC protein {ECO:0000313|EMBL:BAA36694.1}; RhD {ECO:0000313|EMBL:AAN86717.1}; Rhesus blood group D antigen {ECO:0000313|EMBL:AEP84116.1} A7Y8S3 [Target identity:11%; Query identity:100%]Rh blood group D antigen {ECO:0000313|EMBL:AFM38089.1}; Rhesus blood group D antigen {ECO:0000313|EMBL:ABJ90065.1} Q5NDM5 [Target identity:11%; Query identity:100%]Rhesus blood group C antigen {ECO:0000313|EMBL:CAI30431.1} I0CKG6 [Target identity:11%; Query identity:100%]Rh blood group D antigen {ECO:0000313|EMBL:AFH77613.1} A0PFK1 [Target identity:11%; Query identity:100%]Rhesus blood group C antigen {ECO:0000313|EMBL:CAL69447.1} G0TQY3 [Target identity:9%; Query identity:100%]Rhesus blood group D antigen {ECO:0000313|EMBL:CCC42282.1} D8MJ86 [Target identity:9%; Query identity:100%]Truncated Rh blood group D antigen {ECO:0000313|EMBL:CBS91669.1}
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CD markers
Blood group antigen proteins
Transporters
Transporter channels and pores
Predicted membrane proteins
Prediction method-based
Membrane proteins predicted by MDM
MEMSAT3 predicted membrane proteins
MEMSAT-SVM predicted membrane proteins
Phobius predicted membrane proteins
SCAMPI predicted membrane proteins
SPOCTOPUS predicted membrane proteins
THUMBUP predicted membrane proteins
TMHMM predicted membrane proteins
# TM segments-based
>9TM proteins predicted by MDM
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396 |
43.3 |
No |
>9 |
| RHD-007 |
ENSP00000456966
ENST00000568195
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H3BT10
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H3BT10 [Target identity:100%; Query identity:100%]Blood group Rh(D) polypeptide {ECO:0000313|Ensembl:ENSP00000456966} I2HA01 [Target identity:73%; Query identity:100%]Rhesus blood group D antigen {ECO:0000313|EMBL:CCH63384.1} B4F4S0 [Target identity:68%; Query identity:100%]Rhesus blood group, D antigen {ECO:0000313|EMBL:CAQ53124.1} E7BAS5 [Target identity:66%; Query identity:100%]Rhesus blood group, D antigen {ECO:0000313|EMBL:CBY78080.1} B4F4S7 [Target identity:57%; Query identity:100%]Rhesus blood group, D antigen {ECO:0000313|EMBL:CAQ53131.1} I2HA00 [Target identity:55%; Query identity:100%]Rhesus blood group D antigen {ECO:0000313|EMBL:CCH63383.1} B2ZGQ0 [Target identity:27%; Query identity:100%]Truncated Rhesus blood group D antigen {ECO:0000313|EMBL:ACD43642.1} Q9UDZ3 [Target identity:26%; Query identity:100%]RHD protein {ECO:0000313|EMBL:CAB10170.1} P78522 [Target identity:13%; Query identity:100%]Rh blood group C antigen {ECO:0000313|EMBL:AAB39601.1}; Rh blood group D antigen {ECO:0000313|EMBL:AFH77606.1}; Rh blood group, CcEe antigens {ECO:0000313|EMBL:CAS02275.1}; Rh blood group, D antigen {ECO:0000313|EMBL:CBB12662.1} D8MJ84 [Target identity:13%; Query identity:100%]Rh blood group D antigen {ECO:0000313|EMBL:CBS91667.1} Q49IM6 [Target identity:11%; Query identity:100%]Rh blood group D antigen {ECO:0000313|EMBL:AFM38801.1}; Rh blood group, D antigen {ECO:0000313|EMBL:CBM95511.1}; Rhesus blood group D antigen {ECO:0000313|EMBL:AAX63192.1} Q6A1H1 [Target identity:11%; Query identity:100%]Rhesus blood group D antigen {ECO:0000313|EMBL:CAH04922.2} Q9UEC7 [Target identity:10%; Query identity:100%]Rh blood group D antigen {ECO:0000313|EMBL:AGC26023.1}; RhC protein {ECO:0000313|EMBL:BAA36694.1}; RhD {ECO:0000313|EMBL:AAN86717.1}; Rhesus blood group D antigen {ECO:0000313|EMBL:AEP84116.1} D2CRH1 [Target identity:10%; Query identity:100%]Rhesus blood group D antigen {ECO:0000313|EMBL:ACF09154.1} A9P3T3 [Target identity:10%; Query identity:100%]Rh blood group D antigen {ECO:0000313|EMBL:AGC26025.1}; Rh blood group RHD {ECO:0000313|EMBL:AEF57639.1}; RhD antigen {ECO:0000313|EMBL:AEL12218.1}; Rhesus blood group D antigen {ECO:0000313|EMBL:ABO28976.1} A0PFK1 [Target identity:10%; Query identity:100%]Rhesus blood group C antigen {ECO:0000313|EMBL:CAL69447.1} A7Y8S3 [Target identity:9%; Query identity:100%]Rh blood group D antigen {ECO:0000313|EMBL:AFM38089.1}; Rhesus blood group D antigen {ECO:0000313|EMBL:ABJ90065.1} Q5NDM5 [Target identity:9%; Query identity:100%]Rhesus blood group C antigen {ECO:0000313|EMBL:CAI30431.1} I0CKG6 [Target identity:9%; Query identity:100%]Rh blood group D antigen {ECO:0000313|EMBL:AFH77613.1} G0TQY3 [Target identity:7%; Query identity:100%]Rhesus blood group D antigen {ECO:0000313|EMBL:CCC42282.1} D8MJ86 [Target identity:7%; Query identity:100%]Truncated Rh blood group D antigen {ECO:0000313|EMBL:CBS91669.1} W6AWB5 [Target identity:5%; Query identity:100%]Rh blood group D antigen {ECO:0000313|EMBL:AHI63008.1}
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Predicted membrane proteins
Prediction method-based
Membrane proteins predicted by MDM
MEMSAT3 predicted membrane proteins
MEMSAT-SVM predicted membrane proteins
Phobius predicted membrane proteins
SCAMPI predicted membrane proteins
SPOCTOPUS predicted membrane proteins
THUMBUP predicted membrane proteins
TMHMM predicted membrane proteins
# TM segments-based
>9TM proteins predicted by MDM
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463 |
50.2 |
No |
>9 |
| RHD-008 |
ENSP00000339577
ENST00000342055
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Q02161
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Q02161 [Direct mapping]Blood group Rh(D) polypeptide I2HA01 [Target identity:69%; Query identity:100%]Rhesus blood group D antigen {ECO:0000313|EMBL:CCH63384.1} B4F4S0 [Target identity:64%; Query identity:100%]Rhesus blood group, D antigen {ECO:0000313|EMBL:CAQ53124.1} E7BAS5 [Target identity:62%; Query identity:100%]Rhesus blood group, D antigen {ECO:0000313|EMBL:CBY78080.1} B4F4S7 [Target identity:54%; Query identity:100%]Rhesus blood group, D antigen {ECO:0000313|EMBL:CAQ53131.1} I2HA00 [Target identity:51%; Query identity:100%]Rhesus blood group D antigen {ECO:0000313|EMBL:CCH63383.1} Q9UDZ3 [Target identity:25%; Query identity:100%]RHD protein {ECO:0000313|EMBL:CAB10170.1} B2ZGQ0 [Target identity:25%; Query identity:100%]Truncated Rhesus blood group D antigen {ECO:0000313|EMBL:ACD43642.1} D8MJ84 [Target identity:12%; Query identity:100%]Rh blood group D antigen {ECO:0000313|EMBL:CBS91667.1} P78522 [Target identity:12%; Query identity:100%]Rh blood group C antigen {ECO:0000313|EMBL:AAB39601.1}; Rh blood group D antigen {ECO:0000313|EMBL:AFH77606.1}; Rh blood group, CcEe antigens {ECO:0000313|EMBL:CAS02275.1}; Rh blood group, D antigen {ECO:0000313|EMBL:CBB12662.1} Q49IM6 [Target identity:11%; Query identity:100%]Rh blood group D antigen {ECO:0000313|EMBL:AFM38801.1}; Rh blood group, D antigen {ECO:0000313|EMBL:CBM95511.1}; Rhesus blood group D antigen {ECO:0000313|EMBL:AAX63192.1} A9P3T3 [Target identity:10%; Query identity:100%]Rh blood group D antigen {ECO:0000313|EMBL:AGC26025.1}; Rh blood group RHD {ECO:0000313|EMBL:AEF57639.1}; RhD antigen {ECO:0000313|EMBL:AEL12218.1}; Rhesus blood group D antigen {ECO:0000313|EMBL:ABO28976.1} Q6A1H1 [Target identity:10%; Query identity:100%]Rhesus blood group D antigen {ECO:0000313|EMBL:CAH04922.2} D2CRH1 [Target identity:9%; Query identity:100%]Rhesus blood group D antigen {ECO:0000313|EMBL:ACF09154.1} Q9UEC7 [Target identity:9%; Query identity:100%]Rh blood group D antigen {ECO:0000313|EMBL:AGC26023.1}; RhC protein {ECO:0000313|EMBL:BAA36694.1}; RhD {ECO:0000313|EMBL:AAN86717.1}; Rhesus blood group D antigen {ECO:0000313|EMBL:AEP84116.1} I0CKG6 [Target identity:9%; Query identity:100%]Rh blood group D antigen {ECO:0000313|EMBL:AFH77613.1} A0PFK1 [Target identity:9%; Query identity:100%]Rhesus blood group C antigen {ECO:0000313|EMBL:CAL69447.1} Q5NDM5 [Target identity:9%; Query identity:100%]Rhesus blood group C antigen {ECO:0000313|EMBL:CAI30431.1} A7Y8S3 [Target identity:8%; Query identity:100%]Rh blood group D antigen {ECO:0000313|EMBL:AFM38089.1}; Rhesus blood group D antigen {ECO:0000313|EMBL:ABJ90065.1} G0TQY3 [Target identity:7%; Query identity:100%]Rhesus blood group D antigen {ECO:0000313|EMBL:CCC42282.1} D8MJ86 [Target identity:7%; Query identity:100%]Truncated Rh blood group D antigen {ECO:0000313|EMBL:CBS91669.1}
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CD markers
Blood group antigen proteins
Transporters
Transporter channels and pores
Predicted membrane proteins
Prediction method-based
Membrane proteins predicted by MDM
MEMSAT3 predicted membrane proteins
MEMSAT-SVM predicted membrane proteins
Phobius predicted membrane proteins
SCAMPI predicted membrane proteins
SPOCTOPUS predicted membrane proteins
THUMBUP predicted membrane proteins
TMHMM predicted membrane proteins
# TM segments-based
>9TM proteins predicted by MDM
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493 |
53.6 |
No |
>9 |
| RHD-009 |
ENSP00000399640
ENST00000423810
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E7EVW1
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E7EVW1 [Target identity:100%; Query identity:100%]Blood group Rh(D) polypeptide {ECO:0000313|Ensembl:ENSP00000399640} I2HA01 [Target identity:79%; Query identity:100%]Rhesus blood group D antigen {ECO:0000313|EMBL:CCH63384.1} B4F4S0 [Target identity:73%; Query identity:100%]Rhesus blood group, D antigen {ECO:0000313|EMBL:CAQ53124.1} E7BAS5 [Target identity:71%; Query identity:100%]Rhesus blood group, D antigen {ECO:0000313|EMBL:CBY78080.1} B4F4S7 [Target identity:62%; Query identity:100%]Rhesus blood group, D antigen {ECO:0000313|EMBL:CAQ53131.1} I2HA00 [Target identity:59%; Query identity:100%]Rhesus blood group D antigen {ECO:0000313|EMBL:CCH63383.1} B2ZGQ0 [Target identity:29%; Query identity:100%]Truncated Rhesus blood group D antigen {ECO:0000313|EMBL:ACD43642.1} Q9UDZ3 [Target identity:28%; Query identity:100%]RHD protein {ECO:0000313|EMBL:CAB10170.1} D8MJ84 [Target identity:14%; Query identity:100%]Rh blood group D antigen {ECO:0000313|EMBL:CBS91667.1} P78522 [Target identity:14%; Query identity:100%]Rh blood group C antigen {ECO:0000313|EMBL:AAB39601.1}; Rh blood group D antigen {ECO:0000313|EMBL:AFH77606.1}; Rh blood group, CcEe antigens {ECO:0000313|EMBL:CAS02275.1}; Rh blood group, D antigen {ECO:0000313|EMBL:CBB12662.1} Q6A1H1 [Target identity:12%; Query identity:100%]Rhesus blood group D antigen {ECO:0000313|EMBL:CAH04922.2} Q49IM6 [Target identity:12%; Query identity:100%]Rh blood group D antigen {ECO:0000313|EMBL:AFM38801.1}; Rh blood group, D antigen {ECO:0000313|EMBL:CBM95511.1}; Rhesus blood group D antigen {ECO:0000313|EMBL:AAX63192.1} Q9UEC7 [Target identity:11%; Query identity:100%]Rh blood group D antigen {ECO:0000313|EMBL:AGC26023.1}; RhC protein {ECO:0000313|EMBL:BAA36694.1}; RhD {ECO:0000313|EMBL:AAN86717.1}; Rhesus blood group D antigen {ECO:0000313|EMBL:AEP84116.1} D2CRH1 [Target identity:11%; Query identity:100%]Rhesus blood group D antigen {ECO:0000313|EMBL:ACF09154.1} A9P3T3 [Target identity:11%; Query identity:100%]Rh blood group D antigen {ECO:0000313|EMBL:AGC26025.1}; Rh blood group RHD {ECO:0000313|EMBL:AEF57639.1}; RhD antigen {ECO:0000313|EMBL:AEL12218.1}; Rhesus blood group D antigen {ECO:0000313|EMBL:ABO28976.1} I0CKG6 [Target identity:10%; Query identity:100%]Rh blood group D antigen {ECO:0000313|EMBL:AFH77613.1} Q5NDM5 [Target identity:10%; Query identity:100%]Rhesus blood group C antigen {ECO:0000313|EMBL:CAI30431.1} A7Y8S3 [Target identity:10%; Query identity:100%]Rh blood group D antigen {ECO:0000313|EMBL:AFM38089.1}; Rhesus blood group D antigen {ECO:0000313|EMBL:ABJ90065.1} A0PFK1 [Target identity:10%; Query identity:100%]Rhesus blood group C antigen {ECO:0000313|EMBL:CAL69447.1} G0TQY3 [Target identity:8%; Query identity:100%]Rhesus blood group D antigen {ECO:0000313|EMBL:CCC42282.1} D8MJ86 [Target identity:8%; Query identity:100%]Truncated Rh blood group D antigen {ECO:0000313|EMBL:CBS91669.1}
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Predicted membrane proteins
Prediction method-based
Membrane proteins predicted by MDM
MEMSAT3 predicted membrane proteins
MEMSAT-SVM predicted membrane proteins
Phobius predicted membrane proteins
SCAMPI predicted membrane proteins
SPOCTOPUS predicted membrane proteins
THUMBUP predicted membrane proteins
TMHMM predicted membrane proteins
# TM segments-based
>9TM proteins predicted by MDM
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431 |
46.3 |
No |
>9 |
| RHD-201 |
ENSP00000480925
ENST00000615607
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B4F4S7
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B4F4S7 [Target identity:88%; Query identity:100%]Rhesus blood group, D antigen {ECO:0000313|EMBL:CAQ53131.1} I2HA00 [Target identity:84%; Query identity:100%]Rhesus blood group D antigen {ECO:0000313|EMBL:CCH63383.1} B2ZGQ0 [Target identity:42%; Query identity:100%]Truncated Rhesus blood group D antigen {ECO:0000313|EMBL:ACD43642.1} D8MJ84 [Target identity:20%; Query identity:100%]Rh blood group D antigen {ECO:0000313|EMBL:CBS91667.1} P78522 [Target identity:20%; Query identity:100%]Rh blood group C antigen {ECO:0000313|EMBL:AAB39601.1}; Rh blood group D antigen {ECO:0000313|EMBL:AFH77606.1}; Rh blood group, CcEe antigens {ECO:0000313|EMBL:CAS02275.1}; Rh blood group, D antigen {ECO:0000313|EMBL:CBB12662.1} Q49IM6 [Target identity:18%; Query identity:100%]Rh blood group D antigen {ECO:0000313|EMBL:AFM38801.1}; Rh blood group, D antigen {ECO:0000313|EMBL:CBM95511.1}; Rhesus blood group D antigen {ECO:0000313|EMBL:AAX63192.1} Q6A1H1 [Target identity:17%; Query identity:100%]Rhesus blood group D antigen {ECO:0000313|EMBL:CAH04922.2} A9P3T3 [Target identity:16%; Query identity:100%]Rh blood group D antigen {ECO:0000313|EMBL:AGC26025.1}; Rh blood group RHD {ECO:0000313|EMBL:AEF57639.1}; RhD antigen {ECO:0000313|EMBL:AEL12218.1}; Rhesus blood group D antigen {ECO:0000313|EMBL:ABO28976.1} D2CRH1 [Target identity:16%; Query identity:100%]Rhesus blood group D antigen {ECO:0000313|EMBL:ACF09154.1} Q9UEC7 [Target identity:16%; Query identity:100%]Rh blood group D antigen {ECO:0000313|EMBL:AGC26023.1}; RhC protein {ECO:0000313|EMBL:BAA36694.1}; RhD {ECO:0000313|EMBL:AAN86717.1}; Rhesus blood group D antigen {ECO:0000313|EMBL:AEP84116.1} A0PFK1 [Target identity:15%; Query identity:100%]Rhesus blood group C antigen {ECO:0000313|EMBL:CAL69447.1} D8MJ86 [Target identity:12%; Query identity:100%]Truncated Rh blood group D antigen {ECO:0000313|EMBL:CBS91669.1} G0TQY3 [Target identity:12%; Query identity:100%]Rhesus blood group D antigen {ECO:0000313|EMBL:CCC42282.1}
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Predicted membrane proteins
Prediction method-based
Membrane proteins predicted by MDM
MEMSAT3 predicted membrane proteins
MEMSAT-SVM predicted membrane proteins
Phobius predicted membrane proteins
SCAMPI predicted membrane proteins
SPOCTOPUS predicted membrane proteins
THUMBUP predicted membrane proteins
TMHMM predicted membrane proteins
# TM segments-based
9TM proteins predicted by MDM
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302 |
32.9 |
No |
9 |
| RHD-202 |
ENSP00000478087
ENST00000622561
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E7EVW1
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E7EVW1 [Target identity:100%; Query identity:100%]Blood group Rh(D) polypeptide {ECO:0000313|Ensembl:ENSP00000399640} I2HA01 [Target identity:79%; Query identity:100%]Rhesus blood group D antigen {ECO:0000313|EMBL:CCH63384.1} B4F4S0 [Target identity:73%; Query identity:100%]Rhesus blood group, D antigen {ECO:0000313|EMBL:CAQ53124.1} E7BAS5 [Target identity:71%; Query identity:100%]Rhesus blood group, D antigen {ECO:0000313|EMBL:CBY78080.1} B4F4S7 [Target identity:62%; Query identity:100%]Rhesus blood group, D antigen {ECO:0000313|EMBL:CAQ53131.1} I2HA00 [Target identity:59%; Query identity:100%]Rhesus blood group D antigen {ECO:0000313|EMBL:CCH63383.1} B2ZGQ0 [Target identity:29%; Query identity:100%]Truncated Rhesus blood group D antigen {ECO:0000313|EMBL:ACD43642.1} Q9UDZ3 [Target identity:28%; Query identity:100%]RHD protein {ECO:0000313|EMBL:CAB10170.1} D8MJ84 [Target identity:14%; Query identity:100%]Rh blood group D antigen {ECO:0000313|EMBL:CBS91667.1} P78522 [Target identity:14%; Query identity:100%]Rh blood group C antigen {ECO:0000313|EMBL:AAB39601.1}; Rh blood group D antigen {ECO:0000313|EMBL:AFH77606.1}; Rh blood group, CcEe antigens {ECO:0000313|EMBL:CAS02275.1}; Rh blood group, D antigen {ECO:0000313|EMBL:CBB12662.1} Q6A1H1 [Target identity:12%; Query identity:100%]Rhesus blood group D antigen {ECO:0000313|EMBL:CAH04922.2} Q49IM6 [Target identity:12%; Query identity:100%]Rh blood group D antigen {ECO:0000313|EMBL:AFM38801.1}; Rh blood group, D antigen {ECO:0000313|EMBL:CBM95511.1}; Rhesus blood group D antigen {ECO:0000313|EMBL:AAX63192.1} Q9UEC7 [Target identity:11%; Query identity:100%]Rh blood group D antigen {ECO:0000313|EMBL:AGC26023.1}; RhC protein {ECO:0000313|EMBL:BAA36694.1}; RhD {ECO:0000313|EMBL:AAN86717.1}; Rhesus blood group D antigen {ECO:0000313|EMBL:AEP84116.1} D2CRH1 [Target identity:11%; Query identity:100%]Rhesus blood group D antigen {ECO:0000313|EMBL:ACF09154.1} A9P3T3 [Target identity:11%; Query identity:100%]Rh blood group D antigen {ECO:0000313|EMBL:AGC26025.1}; Rh blood group RHD {ECO:0000313|EMBL:AEF57639.1}; RhD antigen {ECO:0000313|EMBL:AEL12218.1}; Rhesus blood group D antigen {ECO:0000313|EMBL:ABO28976.1} I0CKG6 [Target identity:10%; Query identity:100%]Rh blood group D antigen {ECO:0000313|EMBL:AFH77613.1} Q5NDM5 [Target identity:10%; Query identity:100%]Rhesus blood group C antigen {ECO:0000313|EMBL:CAI30431.1} A7Y8S3 [Target identity:10%; Query identity:100%]Rh blood group D antigen {ECO:0000313|EMBL:AFM38089.1}; Rhesus blood group D antigen {ECO:0000313|EMBL:ABJ90065.1} A0PFK1 [Target identity:10%; Query identity:100%]Rhesus blood group C antigen {ECO:0000313|EMBL:CAL69447.1} G0TQY3 [Target identity:8%; Query identity:100%]Rhesus blood group D antigen {ECO:0000313|EMBL:CCC42282.1} D8MJ86 [Target identity:8%; Query identity:100%]Truncated Rh blood group D antigen {ECO:0000313|EMBL:CBS91669.1}
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Predicted membrane proteins
Prediction method-based
Membrane proteins predicted by MDM
MEMSAT3 predicted membrane proteins
MEMSAT-SVM predicted membrane proteins
Phobius predicted membrane proteins
SCAMPI predicted membrane proteins
SPOCTOPUS predicted membrane proteins
THUMBUP predicted membrane proteins
TMHMM predicted membrane proteins
# TM segments-based
>9TM proteins predicted by MDM
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431 |
46.3 |
No |
>9 |
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