AGTR2

GENERAL INFORMATION

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Gene name

AGTR2

Gene description

Angiotensin II receptor, type 2

Protein class

G-protein coupled receptors
Predicted membrane proteins

Predicted localization

Membrane

Number of transcripts

1
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Group enriched (endometrium, fallopian tube, lung, smooth muscle)
GTEx:Tissue enhanced (fallopian tube, lung)

Protein evidence

Evidence at protein level

ANTIBODY RELIABILITY

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Data reliability

Pending normal tissue annotation.
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
N/A
Endocrine tissues
N/A
Bone marrow & immune system
N/A
Muscle tissues
N/A
Lung
N/A
Nasopharynx
N/A
N/A
Bronchus
N/A
N/A
Lung
N/A
Liver & gallbladder
N/A
Liver
N/A
Pancreas
N/A
Pancreas
N/A
Gastrointestinal tract
N/A
Kidney & urinary bladder
N/A
Male tissues
N/A
Testis
N/A
Epididymis
N/A
N/A
Prostate
N/A
Seminal vesicle
N/A
N/A
Female tissues
N/A
Breast
N/A
N/A
Vagina
N/A
N/A
Cervix, uterine
N/A
N/A
Ovary
N/A
Placenta
N/A
Adipose & soft tissue
N/A
Skin
N/A
Skin
N/A


PROTEIN EXPRESSION OVERVIEW

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Pending normal tissue annotation.


RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Group enriched (endometrium, fallopian tube, lung, smooth muscle)

Organ

Expression

GTEx dataset
RNA tissue category:  Tissue enhanced (fallopian tube, lung)

Organ

Expression



GENE INFORMATION

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Gene name

AGTR2 (HGNC Symbol)

Synonyms

AT2, MRX88

Description

Angiotensin II receptor, type 2 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene belongs to the G-protein coupled receptor 1 family, and functions as a receptor for angiotensin II. It is an intergral membrane protein that is highly expressed in fetus, but scantily in adult tissues, except brain, adrenal medulla, and atretic ovary. This receptor has been shown to mediate programmed cell death and this apoptotic function may play an important role in developmental biology and pathophysiology. Mutations in this gene are been associated with X-linked mental retardation. [provided by RefSeq, Jan 2010]

Chromosome

X

Cytoband

q23

Chromosome location (bp)

116170722 - 116174972

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000180772 (version 78.38)

Entrez gene

186

UniProt

P50052 (UniProt - Evidence at protein level)

neXtProt

NX_P50052

Antibodypedia

AGTR2 antibodies


PROTEIN BROWSER

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ENST00000371906
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

AGTR2-001 ENSP00000360973
ENST00000371906
P50052
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