NDUFV2

GENE INFORMATION

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Gene name

NDUFV2 (HGNC Symbol)

Synonyms

CI-24k

Description

NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa (HGNC Symbol)

Entrez gene summary

The NADH-ubiquinone oxidoreductase complex (complex I) of the mitochondrial respiratory chain catalyzes the transfer of electrons from NADH to ubiquinone, and consists of at least 43 subunits. The complex is located in the inner mitochondrial membrane. This gene encodes the 24 kDa subunit of complex I, and is involved in electron transfer. Mutations in this gene are implicated in Parkinson's disease, bipolar disorder, schizophrenia, and have been found in one case of early onset hypertrophic cardiomyopathy and encephalopathy. A non-transcribed pseudogene of this locus is found on chromosome 19. [provided by RefSeq, Oct 2009]

Chromosome

18

Cytoband

p11.22

Chromosome location (bp)

9102630 - 9134345

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000178127 (version 78.38)

Entrez gene

4729

UniProt

P19404 (UniProt - Evidence at protein level)

neXtProt

NX_P19404

Antibodypedia

NDUFV2 antibodies
 

PROTEIN VIEW

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NDUFV2-001
 
NDUFV2-002
 
NDUFV2-003
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

NDUFV2-001 ENSP00000327268
ENST00000318388
P19404
Show all »
Show » Show » 249 27.4 No 0
NDUFV2-002 ENSP00000382908
ENST00000400033
E7EPT4
Show all »
Show » Show » 252 27.9 No 0
NDUFV2-003 ENSP00000464504
ENST00000497577
J3QS34
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Show » 21 2.4 No 0