FKBP2

GENE INFORMATION

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Gene name

FKBP2 (HGNC Symbol)

Synonyms

FKBP-13, PPIase

Description

FK506 binding protein 2, 13kDa (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It is thought to function as an ER chaperone and may also act as a component of membrane cytoskeletal scaffolds. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Sep 2008]

Chromosome

11

Cytoband

q13.1

Chromosome location (bp)

64241003 - 64244132

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000173486 (version 78.38)

Entrez gene

2286

UniProt

P26885 (UniProt - Evidence at protein level)

neXtProt

NX_P26885

Antibodypedia

FKBP2 antibodies
 

PROTEIN VIEW

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FKBP2-001
 
FKBP2-003
 
FKBP2-004
 
FKBP2-005
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

FKBP2-001 ENSP00000378046
ENST00000394540
P26885
Show all »
Show » Show » 142 15.6 Yes 0
FKBP2-003 ENSP00000310935
ENST00000309366
P26885
Show all »
Show » Show » 142 15.6 Yes 0
FKBP2-004 ENSP00000398147
ENST00000449942
P26885
Show all »
Show » Show » 142 15.6 Yes 0
FKBP2-005 ENSP00000438749
ENST00000535135
F5H0N4
Show all »
Show » Show » 102 11.3 Yes 0