SP7

GENE INFORMATION

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Gene name

SP7 (HGNC Symbol)

Synonyms

osterix, OSX

Description

Sp7 transcription factor (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the Sp subfamily of Sp/XKLF transcription factors. Sp family proteins are sequence-specific DNA-binding proteins characterized by an amino-terminal trans-activation domain and three carboxy-terminal zinc finger motifs. This protein is a bone specific transcription factor and is required for osteoblast differentiation and bone formation.[provided by RefSeq, Jul 2010]

Chromosome

12

Cytoband

q13.13

Chromosome location (bp)

53326575 - 53345315

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000170374 (version 78.38)

Entrez gene

121340

UniProt

Q8TDD2 (UniProt - Evidence at protein level)

neXtProt

NX_Q8TDD2

Antibodypedia

SP7 antibodies
 

PROTEIN VIEW

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SP7-001
 
SP7-002
 
SP7-003
 
SP7-005
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SP7-001 ENSP00000443827
ENST00000536324
Q8TDD2
Show all »
Show » Show » 431 45 No 0
SP7-002 ENSP00000302812
ENST00000303846
Q8TDD2
Show all »
Show » Show » 431 45 No 0
SP7-003 ENSP00000441367
ENST00000537210
Q8TDD2
Show all »
Show » Show » 413 43.1 No 0
SP7-005 ENSP00000449355
ENST00000547755
F8VV67
Show all »
Show » 269 27 No 0