APLF

ANTIBODY PRIMARY DATA

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Antibodies in assay

HPA029396 , HPA034642 , HPA034643
 

Tissue presentation order  

Organ

Cell type

Alphabetical

 

Tissue

Antibody staining

Annotated expression

Liver & gallbladder
Liver Hepatocytes
Liver Bile duct cells
Gallbladder Glandular cells
Pancreas
Pancreas Exocrine glandular cells
Pancreas Islets of Langerhans
Gastrointestinal tract
Oral mucosa Squamous epithelial cells
Salivary gland Glandular cells
Esophagus Squamous epithelial cells
Stomach 1 Glandular cells
Stomach 2 Glandular cells
Duodenum Glandular cells
Small intestine Glandular cells
Colon Endothelial cells
Colon Glandular cells
Colon Peripheral nerve/ganglion
Rectum Glandular cells
Bone marrow & immune system
Appendix Glandular cells
Appendix Lymphoid tissue
Kidney & urinary bladder
Kidney Cells in glomeruli
Kidney Cells in tubules
Urinary bladder Urothelial cells
Male reproductive system
Testis Cells in seminiferous ducts
Testis Leydig cells
Epididymis Glandular cells
Prostate Glandular cells
Seminal vesicle Glandular cells
Breast and female reproductive system
Breast Adipocytes
Breast Glandular cells
Breast Myoepithelial cells
Vagina Squamous epithelial cells
Cervix, uterine Squamous epithelial cells
Cervix, uterine Glandular cells
Endometrium 1 Glandular cells
Endometrium 1 Cells in endometrial stroma
Endometrium 2 Glandular cells
Endometrium 2 Cells in endometrial stroma
Fallopian tube Glandular cells
Ovary Follicle cells
Ovary Ovarian stroma cells
Placenta Trophoblastic cells
Placenta Decidual cells
   
HPA029396
HPA034642
HPA034643
  

Tissue

Antibody staining

Annotated expression

Skin
Skin 1 Fibroblasts
Skin 1 Keratinocytes
Skin 1 Langerhans
Skin 1 Melanocytes
Skin 2 Epidermal cells
Bone marrow & immune system
Bone marrow Hematopoietic cells
Lymph node Germinal center cells
Lymph node Non-germinal center cells
Tonsil Germinal center cells
Tonsil Non-germinal center cells
Tonsil Squamous epithelial cells
Spleen Cells in white pulp
Spleen Cells in red pulp
Central nervous system (Brain)
Cerebral cortex Neuronal cells
Cerebral cortex Endothelial cells
Cerebral cortex Glial cells
Cerebral cortex Neuropil
Hippocampus Neuronal cells
Hippocampus Glial cells
Lateral ventricle Neuronal cells
Lateral ventricle Glial cells
Cerebellum Purkinje cells
Cerebellum Cells in granular layer
Cerebellum Cells in molecular layer
Endocrine tissues
Thyroid gland Glandular cells
Parathyroid gland Glandular cells
Adrenal gland Glandular cells
Respiratory system
Nasopharynx Respiratory epithelial cells
Bronchus Respiratory epithelial cells
Lung Pneumocytes
Lung Macrophages
Muscle tissues
Heart muscle Myocytes
Skeletal muscle Myocytes
Smooth muscle Smooth muscle cells
Adipose & soft tissue
Soft tissue 1 Adipocytes
Soft tissue 1 Peripheral nerve
Soft tissue 1 Chondrocytes
Soft tissue 1 Fibroblasts
Soft tissue 2 Adipocytes
Soft tissue 2 Fibroblasts
Soft tissue 2 Chondrocytes
Soft tissue 2 Peripheral nerve
   
HPA029396
HPA034642
HPA034643
 

Staining summary

HPA029396 Most normal tissues displayed moderate granular cytoplasmic immunoreactivity. Strong staining was for example observed in intestinal Paneth cells, lymphoid germinal center cells, heart muscle, endometrial and cervical glands. Glial cells were generally negative.
HPA034642 Normal tissues displayed moderate to strong nuclear positivity with additional granular cytoplasmic staining in several cases.
HPA034643 Most normal tissues showed weak to moderate cytoplasmic staining with occasional nuclear positivity, for example in placenta. Hepatocytes were strongly stained. Cells in CNS, lymphoid tissues and myocytes were generally negative.
 

Level of antibody staining/expression





High
Medium
Low
Not detected