ADAM9

GENERAL INFORMATION

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Gene name

ADAM9

Gene description

ADAM metallopeptidase domain 9

Protein class

Cancer-related genes
Disease related genes
Enzymes
Plasma proteins
Potential drug targets
Predicted membrane proteins
Predicted secreted proteins

Predicted localization

Membrane,Secreted

Number of transcripts

3
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

Neuronal cells in CNS, showed moderate to strong cytoplasmic positivity. Decidual cells in placenta and squamous epithelium in skin displayed nuclear membrane immunoreactivity. Remaining normal cells were weakly stained or negative.

ANTIBODY RELIABILITY

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Data reliability
description

Pending RNA-based expert annotation.

Data reliability

Uncertain based on 1 antibody.
HPA004000
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Expressed in all

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

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Gene name

ADAM9 (HGNC Symbol)

Synonyms

CORD9, KIAA0021, MCMP, MDC9, Mltng

Description

ADAM metallopeptidase domain 9 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene interacts with SH3 domain-containing proteins, binds mitotic arrest deficient 2 beta protein, and is also involved in TPA-induced ectodomain shedding of membrane-anchored heparin-binding EGF-like growth factor. Several alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, Jul 2010]

Chromosome

8

Cytoband

p11.22

Chromosome location (bp)

38996869 - 39105144

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000168615 (version 78.38)

Entrez gene

8754

UniProt

Q13443 (UniProt - Evidence at protein level)

neXtProt

NX_Q13443

Antibodypedia

ADAM9 antibodies


PROTEIN BROWSER

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ENST00000466936
 
ENST00000481513
 
ENST00000487273
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ADAM9-001 ENSP00000419446
ENST00000487273
Q13443
Show all »
Show » Show » 819 90.6 Yes 1
ADAM9-002 ENSP00000417066
ENST00000481513
C9J6H5
Show all »
Show » Show » 128 14.7 Yes 0
ADAM9-003 ENSP00000420257
ENST00000466936
C9JPM3
Show all »
Show » Show » 147 16.8 Yes 0