CTNNB1 - Gene info - The Human Protein Atlas

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Field

Term

CTNNB1-001		CTNNB1-002		CTNNB1-003		CTNNB1-005		CTNNB1-007		CTNNB1-010		CTNNB1-011		CTNNB1-012		CTNNB1-013		CTNNB1-014

P35222 [Direct mapping]
Catenin beta-1
A0A024R2Q3 [Target identity:100%; Query identity:100%]
Catenin (Cadherin-associated protein), beta 1, 88kDa, isoform CRA_a {ECO:0000313|EMBL:EAW64628.1}
B4DGU4 [Target identity:99%; Query identity:100%]
Catenin beta-1 {ECO:0000313|Ensembl:ENSP00000411226}; cDNA FLJ57878, highly similar to Beta-catenin {ECO:0000313|EMBL:BAG57905.1}
E7EMJ5 [Target identity:19%; Query identity:100%]
Catenin beta-1 {ECO:0000313|Ensembl:ENSP00000412219}
E7EV28 [Target identity:13%; Query identity:100%]
Catenin beta-1 {ECO:0000313|Ensembl:ENSP00000409302}
E9PDF9 [Target identity:12%; Query identity:100%]
Catenin beta-1 {ECO:0000313|Ensembl:ENSP00000401599}
G9GAG7 [Target identity:9%; Query identity:100%]
Cadherin-associated protein {ECO:0000313|EMBL:AEW16366.1}
C9IZ65 [Target identity:7%; Query identity:100%]
Catenin beta-1 {ECO:0000313|Ensembl:ENSP00000400508}

Predicted intracellular proteins
Plasma proteins
Cancer-related genes
   Candidate cancer biomarkers
   Mutated cancer genes
   Mutational cancer driver genes
   COSMIC somatic mutations in cancer genes
   COSMIC Somatic Mutations
   COSMIC Other Mutations
   COSMIC Missense Mutations
   COSMIC Translocations
Disease related genes
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)

GO:0000122 [negative regulation of transcription from RNA polymerase II promoter]
GO:0000578 [embryonic axis specification]
GO:0000904 [cell morphogenesis involved in differentiation]
GO:0001102 [RNA polymerase II activating transcription factor binding]
GO:0001501 [skeletal system development]
GO:0001569 [patterning of blood vessels]
GO:0001570 [vasculogenesis]
GO:0001658 [branching involved in ureteric bud morphogenesis]
GO:0001701 [in utero embryonic development]
GO:0001702 [gastrulation with mouth forming second]
GO:0001706 [endoderm formation]
GO:0001708 [cell fate specification]
GO:0001709 [cell fate determination]
GO:0001711 [endodermal cell fate commitment]
GO:0001764 [neuron migration]
GO:0001822 [kidney development]
GO:0001837 [epithelial to mesenchymal transition]
GO:0001840 [neural plate development]
GO:0001889 [liver development]
GO:0001944 [vasculature development]
GO:0002052 [positive regulation of neuroblast proliferation]
GO:0002053 [positive regulation of mesenchymal cell proliferation]
GO:0002089 [lens morphogenesis in camera-type eye]
GO:0003136 [negative regulation of heart induction by canonical Wnt signaling pathway]
GO:0003266 [regulation of secondary heart field cardioblast proliferation]
GO:0003337 [mesenchymal to epithelial transition involved in metanephros morphogenesis]
GO:0003338 [metanephros morphogenesis]
GO:0003677 [DNA binding]
GO:0003682 [chromatin binding]
GO:0003690 [double-stranded DNA binding]
GO:0003700 [sequence-specific DNA binding transcription factor activity]
GO:0003713 [transcription coactivator activity]
GO:0004871 [signal transducer activity]
GO:0005198 [structural molecule activity]
GO:0005488 [binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005667 [transcription factor complex]
GO:0005737 [cytoplasm]
GO:0005813 [centrosome]
GO:0005829 [cytosol]
GO:0005886 [plasma membrane]
GO:0005911 [cell-cell junction]
GO:0005912 [adherens junction]
GO:0005913 [cell-cell adherens junction]
GO:0005915 [zonula adherens]
GO:0005916 [fascia adherens]
GO:0005923 [tight junction]
GO:0005925 [focal adhesion]
GO:0005938 [cell cortex]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006357 [regulation of transcription from RNA polymerase II promoter]
GO:0006915 [apoptotic process]
GO:0006921 [cellular component disassembly involved in execution phase of apoptosis]
GO:0007016 [cytoskeletal anchoring at plasma membrane]
GO:0007155 [cell adhesion]
GO:0007160 [cell-matrix adhesion]
GO:0007268 [synaptic transmission]
GO:0007398 [ectoderm development]
GO:0007403 [glial cell fate determination]
GO:0007494 [midgut development]
GO:0007507 [heart development]
GO:0008022 [protein C-terminus binding]
GO:0008134 [transcription factor binding]
GO:0008283 [cell proliferation]
GO:0008284 [positive regulation of cell proliferation]
GO:0008285 [negative regulation of cell proliferation]
GO:0009725 [response to hormone]
GO:0009898 [cytoplasmic side of plasma membrane]
GO:0009948 [anterior/posterior axis specification]
GO:0009950 [dorsal/ventral axis specification]
GO:0009953 [dorsal/ventral pattern formation]
GO:0009954 [proximal/distal pattern formation]
GO:0009987 [cellular process]
GO:0010468 [regulation of gene expression]
GO:0010628 [positive regulation of gene expression]
GO:0010718 [positive regulation of epithelial to mesenchymal transition]
GO:0010909 [positive regulation of heparan sulfate proteoglycan biosynthetic process]
GO:0014010 [Schwann cell proliferation]
GO:0014070 [response to organic cyclic compound]
GO:0014704 [intercalated disc]
GO:0016020 [membrane]
GO:0016055 [Wnt signaling pathway]
GO:0016323 [basolateral plasma membrane]
GO:0016328 [lateral plasma membrane]
GO:0016331 [morphogenesis of embryonic epithelium]
GO:0016337 [single organismal cell-cell adhesion]
GO:0016342 [catenin complex]
GO:0019899 [enzyme binding]
GO:0019900 [kinase binding]
GO:0019901 [protein kinase binding]
GO:0019903 [protein phosphatase binding]
GO:0021819 [layer formation in cerebral cortex]
GO:0022009 [central nervous system vasculogenesis]
GO:0022405 [hair cycle process]
GO:0030018 [Z disc]
GO:0030027 [lamellipodium]
GO:0030054 [cell junction]
GO:0030057 [desmosome]
GO:0030097 [hemopoiesis]
GO:0030154 [cell differentiation]
GO:0030217 [T cell differentiation]
GO:0030316 [osteoclast differentiation]
GO:0030324 [lung development]
GO:0030326 [embryonic limb morphogenesis]
GO:0030331 [estrogen receptor binding]
GO:0030521 [androgen receptor signaling pathway]
GO:0030539 [male genitalia development]
GO:0030856 [regulation of epithelial cell differentiation]
GO:0030858 [positive regulation of epithelial cell differentiation]
GO:0030877 [beta-catenin destruction complex]
GO:0030900 [forebrain development]
GO:0030902 [hindbrain development]
GO:0030997 [regulation of centriole-centriole cohesion]
GO:0031016 [pancreas development]
GO:0031069 [hair follicle morphogenesis]
GO:0031253 [cell projection membrane]
GO:0031528 [microvillus membrane]
GO:0031641 [regulation of myelination]
GO:0032331 [negative regulation of chondrocyte differentiation]
GO:0032355 [response to estradiol]
GO:0032403 [protein complex binding]
GO:0032481 [positive regulation of type I interferon production]
GO:0032993 [protein-DNA complex]
GO:0033077 [T cell differentiation in thymus]
GO:0033234 [negative regulation of protein sumoylation]
GO:0034097 [response to cytokine]
GO:0034332 [adherens junction organization]
GO:0034333 [adherens junction assembly]
GO:0034394 [protein localization to cell surface]
GO:0034613 [cellular protein localization]
GO:0034750 [Scrib-APC-beta-catenin complex]
GO:0035050 [embryonic heart tube development]
GO:0035112 [genitalia morphogenesis]
GO:0035115 [embryonic forelimb morphogenesis]
GO:0035116 [embryonic hindlimb morphogenesis]
GO:0035255 [ionotropic glutamate receptor binding]
GO:0035257 [nuclear hormone receptor binding]
GO:0035315 [hair cell differentiation]
GO:0036023 [embryonic skeletal limb joint morphogenesis]
GO:0042127 [regulation of cell proliferation]
GO:0042129 [regulation of T cell proliferation]
GO:0042475 [odontogenesis of dentin-containing tooth]
GO:0042493 [response to drug]
GO:0042692 [muscle cell differentiation]
GO:0042733 [embryonic digit morphogenesis]
GO:0042981 [regulation of apoptotic process]
GO:0043005 [neuron projection]
GO:0043065 [positive regulation of apoptotic process]
GO:0043123 [positive regulation of I-kappaB kinase/NF-kappaB signaling]
GO:0043198 [dendritic shaft]
GO:0043234 [protein complex]
GO:0043296 [apical junction complex]
GO:0043410 [positive regulation of MAPK cascade]
GO:0043587 [tongue morphogenesis]
GO:0043588 [skin development]
GO:0043627 [response to estrogen]
GO:0044212 [transcription regulatory region DNA binding]
GO:0044325 [ion channel binding]
GO:0044334 [canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition]
GO:0044336 [canonical Wnt signaling pathway involved in negative regulation of apoptotic process]
GO:0045087 [innate immune response]
GO:0045177 [apical part of cell]
GO:0045202 [synapse]
GO:0045294 [alpha-catenin binding]
GO:0045296 [cadherin binding]
GO:0045445 [myoblast differentiation]
GO:0045453 [bone resorption]
GO:0045595 [regulation of cell differentiation]
GO:0045596 [negative regulation of cell differentiation]
GO:0045603 [positive regulation of endothelial cell differentiation]
GO:0045667 [regulation of osteoblast differentiation]
GO:0045669 [positive regulation of osteoblast differentiation]
GO:0045670 [regulation of osteoclast differentiation]
GO:0045671 [negative regulation of osteoclast differentiation]
GO:0045743 [positive regulation of fibroblast growth factor receptor signaling pathway]
GO:0045765 [regulation of angiogenesis]
GO:0045892 [negative regulation of transcription, DNA-templated]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0045944 [positive regulation of transcription from RNA polymerase II promoter]
GO:0046332 [SMAD binding]
GO:0046686 [response to cadmium ion]
GO:0048145 [regulation of fibroblast proliferation]
GO:0048262 [determination of dorsal/ventral asymmetry]
GO:0048469 [cell maturation]
GO:0048471 [perinuclear region of cytoplasm]
GO:0048489 [synaptic vesicle transport]
GO:0048513 [organ development]
GO:0048538 [thymus development]
GO:0048599 [oocyte development]
GO:0048617 [embryonic foregut morphogenesis]
GO:0048660 [regulation of smooth muscle cell proliferation]
GO:0048715 [negative regulation of oligodendrocyte differentiation]
GO:0050681 [androgen receptor binding]
GO:0050808 [synapse organization]
GO:0050998 [nitric-oxide synthase binding]
GO:0051145 [smooth muscle cell differentiation]
GO:0051149 [positive regulation of muscle cell differentiation]
GO:0051291 [protein heterooligomerization]
GO:0060066 [oviduct development]
GO:0060070 [canonical Wnt signaling pathway]
GO:0060173 [limb development]
GO:0060439 [trachea morphogenesis]
GO:0060440 [trachea formation]
GO:0060441 [epithelial tube branching involved in lung morphogenesis]
GO:0060479 [lung cell differentiation]
GO:0060484 [lung-associated mesenchyme development]
GO:0060492 [lung induction]
GO:0060742 [epithelial cell differentiation involved in prostate gland development]
GO:0060769 [positive regulation of epithelial cell proliferation involved in prostate gland development]
GO:0060789 [hair follicle placode formation]
GO:0060916 [mesenchymal cell proliferation involved in lung development]
GO:0061047 [positive regulation of branching involved in lung morphogenesis]
GO:0061154 [endothelial tube morphogenesis]
GO:0061198 [fungiform papilla formation]
GO:0061324 [canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation]
GO:0070062 [extracellular vesicular exosome]
GO:0070369 [beta-catenin-TCF7L2 complex]
GO:0070411 [I-SMAD binding]
GO:0070412 [R-SMAD binding]
GO:0070491 [repressing transcription factor binding]
GO:0070602 [regulation of centromeric sister chromatid cohesion]
GO:0071260 [cellular response to mechanical stimulus]
GO:0071363 [cellular response to growth factor stimulus]
GO:0071407 [cellular response to organic cyclic compound]
GO:0071664 [catenin-TCF7L2 complex]
GO:0071681 [cellular response to indole-3-methanol]
GO:0071944 [cell periphery]
GO:0072001 [renal system development]
GO:0072033 [renal vesicle formation]
GO:0072053 [renal inner medulla development]
GO:0072054 [renal outer medulla development]
GO:0072079 [nephron tubule formation]
GO:0072182 [regulation of nephron tubule epithelial cell differentiation]
GO:0090279 [regulation of calcium ion import]
GO:1901215 [negative regulation of neuron death]
GO:1990314 [cellular response to insulin-like growth factor stimulus]
GO:2000008 [regulation of protein localization to cell surface]
GO:2000017 [positive regulation of determination of dorsal identity]
GO:2001234 [negative regulation of apoptotic signaling pathway]

GO:0000122 [negative regulation of transcription from RNA polymerase II promoter]
GO:0000578 [embryonic axis specification]
GO:0001102 [RNA polymerase II activating transcription factor binding]
GO:0001569 [patterning of blood vessels]
GO:0001658 [branching involved in ureteric bud morphogenesis]
GO:0001702 [gastrulation with mouth forming second]
GO:0001711 [endodermal cell fate commitment]
GO:0001837 [epithelial to mesenchymal transition]
GO:0001889 [liver development]
GO:0003136 [negative regulation of heart induction by canonical Wnt signaling pathway]
GO:0003337 [mesenchymal to epithelial transition involved in metanephros morphogenesis]
GO:0003713 [transcription coactivator activity]
GO:0004871 [signal transducer activity]
GO:0005198 [structural molecule activity]
GO:0005488 [binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005667 [transcription factor complex]
GO:0005737 [cytoplasm]
GO:0005813 [centrosome]
GO:0005829 [cytosol]
GO:0005886 [plasma membrane]
GO:0005911 [cell-cell junction]
GO:0005912 [adherens junction]
GO:0005913 [cell-cell adherens junction]
GO:0005915 [zonula adherens]
GO:0005916 [fascia adherens]
GO:0005925 [focal adhesion]
GO:0005938 [cell cortex]
GO:0006351 [transcription, DNA-templated]
GO:0006915 [apoptotic process]
GO:0006921 [cellular component disassembly involved in execution phase of apoptosis]
GO:0007016 [cytoskeletal anchoring at plasma membrane]
GO:0007155 [cell adhesion]
GO:0007160 [cell-matrix adhesion]
GO:0007398 [ectoderm development]
GO:0007403 [glial cell fate determination]
GO:0008022 [protein C-terminus binding]
GO:0008134 [transcription factor binding]
GO:0008285 [negative regulation of cell proliferation]
GO:0009898 [cytoplasmic side of plasma membrane]
GO:0009950 [dorsal/ventral axis specification]
GO:0009954 [proximal/distal pattern formation]
GO:0010718 [positive regulation of epithelial to mesenchymal transition]
GO:0010909 [positive regulation of heparan sulfate proteoglycan biosynthetic process]
GO:0014010 [Schwann cell proliferation]
GO:0016020 [membrane]
GO:0016055 [Wnt signaling pathway]
GO:0016328 [lateral plasma membrane]
GO:0016337 [single organismal cell-cell adhesion]
GO:0016342 [catenin complex]
GO:0019899 [enzyme binding]
GO:0019900 [kinase binding]
GO:0019901 [protein kinase binding]
GO:0019903 [protein phosphatase binding]
GO:0022009 [central nervous system vasculogenesis]
GO:0030018 [Z disc]
GO:0030027 [lamellipodium]
GO:0030054 [cell junction]
GO:0030057 [desmosome]
GO:0030326 [embryonic limb morphogenesis]
GO:0030331 [estrogen receptor binding]
GO:0030521 [androgen receptor signaling pathway]
GO:0030539 [male genitalia development]
GO:0030877 [beta-catenin destruction complex]
GO:0030902 [hindbrain development]
GO:0030997 [regulation of centriole-centriole cohesion]
GO:0031016 [pancreas development]
GO:0031069 [hair follicle morphogenesis]
GO:0031528 [microvillus membrane]
GO:0032331 [negative regulation of chondrocyte differentiation]
GO:0032355 [response to estradiol]
GO:0032481 [positive regulation of type I interferon production]
GO:0032993 [protein-DNA complex]
GO:0033077 [T cell differentiation in thymus]
GO:0033234 [negative regulation of protein sumoylation]
GO:0034333 [adherens junction assembly]
GO:0034394 [protein localization to cell surface]
GO:0035257 [nuclear hormone receptor binding]
GO:0035315 [hair cell differentiation]
GO:0036023 [embryonic skeletal limb joint morphogenesis]
GO:0042129 [regulation of T cell proliferation]
GO:0042475 [odontogenesis of dentin-containing tooth]
GO:0042493 [response to drug]
GO:0042692 [muscle cell differentiation]
GO:0043065 [positive regulation of apoptotic process]
GO:0043123 [positive regulation of I-kappaB kinase/NF-kappaB signaling]
GO:0043198 [dendritic shaft]
GO:0043410 [positive regulation of MAPK cascade]
GO:0043587 [tongue morphogenesis]
GO:0044212 [transcription regulatory region DNA binding]
GO:0044325 [ion channel binding]
GO:0044334 [canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition]
GO:0044336 [canonical Wnt signaling pathway involved in negative regulation of apoptotic process]
GO:0045087 [innate immune response]
GO:0045202 [synapse]
GO:0045294 [alpha-catenin binding]
GO:0045296 [cadherin binding]
GO:0045669 [positive regulation of osteoblast differentiation]
GO:0045671 [negative regulation of osteoclast differentiation]
GO:0045743 [positive regulation of fibroblast growth factor receptor signaling pathway]
GO:0045765 [regulation of angiogenesis]
GO:0045892 [negative regulation of transcription, DNA-templated]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0045944 [positive regulation of transcription from RNA polymerase II promoter]
GO:0046332 [SMAD binding]
GO:0048145 [regulation of fibroblast proliferation]
GO:0048262 [determination of dorsal/ventral asymmetry]
GO:0048471 [perinuclear region of cytoplasm]
GO:0048489 [synaptic vesicle transport]
GO:0048538 [thymus development]
GO:0048599 [oocyte development]
GO:0048617 [embryonic foregut morphogenesis]
GO:0048660 [regulation of smooth muscle cell proliferation]
GO:0050681 [androgen receptor binding]
GO:0050808 [synapse organization]
GO:0051145 [smooth muscle cell differentiation]
GO:0051149 [positive regulation of muscle cell differentiation]
GO:0060070 [canonical Wnt signaling pathway]
GO:0060440 [trachea formation]
GO:0060479 [lung cell differentiation]
GO:0060484 [lung-associated mesenchyme development]
GO:0060492 [lung induction]
GO:0060769 [positive regulation of epithelial cell proliferation involved in prostate gland development]
GO:0060789 [hair follicle placode formation]
GO:0060916 [mesenchymal cell proliferation involved in lung development]
GO:0061047 [positive regulation of branching involved in lung morphogenesis]
GO:0061154 [endothelial tube morphogenesis]
GO:0061324 [canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation]
GO:0070062 [extracellular vesicular exosome]
GO:0070369 [beta-catenin-TCF7L2 complex]
GO:0070411 [I-SMAD binding]
GO:0070412 [R-SMAD binding]
GO:0070602 [regulation of centromeric sister chromatid cohesion]
GO:0071363 [cellular response to growth factor stimulus]
GO:0071681 [cellular response to indole-3-methanol]
GO:0071944 [cell periphery]
GO:0072033 [renal vesicle formation]
GO:0072053 [renal inner medulla development]
GO:0072054 [renal outer medulla development]
GO:0072079 [nephron tubule formation]
GO:0072182 [regulation of nephron tubule epithelial cell differentiation]
GO:0090279 [regulation of calcium ion import]
GO:2000008 [regulation of protein localization to cell surface]

B4DGU4 [Target identity:100%; Query identity:100%]
Catenin beta-1 {ECO:0000313|Ensembl:ENSP00000411226}; cDNA FLJ57878, highly similar to Beta-catenin {ECO:0000313|EMBL:BAG57905.1}
C9IZ65 [Target identity:7%; Query identity:100%]
Catenin beta-1 {ECO:0000313|Ensembl:ENSP00000400508}

Predicted intracellular proteins
Cancer-related genes
   Mutated cancer genes
   Mutational cancer driver genes
   COSMIC somatic mutations in cancer genes
   COSMIC Somatic Mutations
   COSMIC Other Mutations
   COSMIC Missense Mutations
   COSMIC Translocations
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)

GO:0005488 [binding]
GO:0005515 [protein binding]
GO:0005886 [plasma membrane]

C9IZ65 [Target identity:100%; Query identity:100%]
Catenin beta-1 {ECO:0000313|Ensembl:ENSP00000400508}

E7EMJ5 [Target identity:99%; Query identity:100%]
Catenin beta-1 {ECO:0000313|Ensembl:ENSP00000412219}
E7EV28 [Target identity:72%; Query identity:100%]
Catenin beta-1 {ECO:0000313|Ensembl:ENSP00000409302}
E9PDF9 [Target identity:66%; Query identity:100%]
Catenin beta-1 {ECO:0000313|Ensembl:ENSP00000401599}
G9GAG7 [Target identity:47%; Query identity:100%]
Cadherin-associated protein {ECO:0000313|EMBL:AEW16366.1}
C9IZ65 [Target identity:39%; Query identity:100%]
Catenin beta-1 {ECO:0000313|Ensembl:ENSP00000400508}

GO:0005886 [plasma membrane]

E7EV28 [Target identity:100%; Query identity:100%]
Catenin beta-1 {ECO:0000313|Ensembl:ENSP00000409302}
E9PDF9 [Target identity:92%; Query identity:100%]
Catenin beta-1 {ECO:0000313|Ensembl:ENSP00000401599}
G9GAG7 [Target identity:65%; Query identity:100%]
Cadherin-associated protein {ECO:0000313|EMBL:AEW16366.1}
C9IZ65 [Target identity:54%; Query identity:100%]
Catenin beta-1 {ECO:0000313|Ensembl:ENSP00000400508}

GO:0005886 [plasma membrane]

E9PDF9 [Target identity:100%; Query identity:100%]
Catenin beta-1 {ECO:0000313|Ensembl:ENSP00000401599}
G9GAG7 [Target identity:71%; Query identity:100%]
Cadherin-associated protein {ECO:0000313|EMBL:AEW16366.1}
C9IZ65 [Target identity:59%; Query identity:100%]
Catenin beta-1 {ECO:0000313|Ensembl:ENSP00000400508}

GO:0005886 [plasma membrane]

The Human Protein Atlas project is funded by the Knut & Alice Wallenberg foundation.