UGCG

GENERAL INFORMATION

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Gene name

UGCG

Gene description

UDP-glucose ceramide glucosyltransferase

Protein class

Enzymes
FDA approved drug targets
Predicted membrane proteins
Transporters

Predicted localization

Membrane

Number of transcripts

1
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

Cytoplasmic expression in several tissues.

ANTIBODY RELIABILITY

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Data reliability
description

Antibody staining mainly consistent with RNA expression data.

Data reliability

Uncertain based on 1 antibody.
HPA024124
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Expressed in all

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

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Gene name

UGCG (HGNC Symbol)

Synonyms

GCS

Description

UDP-glucose ceramide glucosyltransferase (HGNC Symbol)

Entrez gene summary

This gene encodes an enzyme that catalyzes the first glycosylation step in the biosynthesis of glycosphingolipids, which are membrane components containing lipid and sugar moieties. The product of this reaction is glucosylceramide, which is the core structure of many glycosphingolipids. [provided by RefSeq, Dec 2014]

Chromosome

9

Cytoband

q31.3

Chromosome location (bp)

111896766 - 111935369

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000148154 (version 78.38)

Entrez gene

7357

UniProt

Q16739 (UniProt - Evidence at protein level)

neXtProt

NX_Q16739

Antibodypedia

UGCG antibodies


PROTEIN BROWSER

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ENST00000374279
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

UGCG-001 ENSP00000363397
ENST00000374279
Q16739
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