EPHA5

GENE INFORMATION

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Gene name

EPHA5 (HGNC Symbol)

Synonyms

CEK7, EHK1, Hek7, TYRO4

Description

EPH receptor A5 (HGNC Symbol)

Entrez gene summary

This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Aug 2013]

Chromosome

4

Cytoband

Chromosome location (bp)

65319563 - 65670495

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000145242 (version 78.38)

Entrez gene

2044

UniProt

P54756 (UniProt - Evidence at protein level)

neXtProt

NX_P54756

Antibodypedia

EPHA5 antibodies
 

PROTEIN VIEW

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EPHA5-001
 
EPHA5-002
 
EPHA5-003
 
EPHA5-004
 
EPHA5-201
 
EPHA5-202
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

EPHA5-001 ENSP00000273854
ENST00000273854
P54756
Show all »
Show » Show » 1037 114.8 No 2
EPHA5-002 ENSP00000346899
ENST00000354839
P54756
Show all »
Show » Show » 1015 112.6 No 1
EPHA5-003 ENSP00000389208
ENST00000432638
F8W9W0
Show all »
Show » Show » 874 96.9 No 2
EPHA5-004 ENSP00000427638
ENST00000511294
F8VP57
Show all »
Show » Show » 1004 111 No 2
EPHA5-201 ENSP00000478537
ENST00000613740
B7ZKW7
Show all »
Show » Show » 1016 112.7 No 1
EPHA5-202 ENSP00000480763
ENST00000622150
B7ZKJ3
Show all »
Show » Show » 1038 114.8 No 2