ABCC12

GENE INFORMATION

? »

Gene name

ABCC12 (HGNC Symbol)

Synonyms

MRP9

Description

ATP-binding cassette, sub-family C (CFTR/MRP), member 12 (HGNC Symbol)

Entrez gene summary

This gene is a member of the superfamily of ATP-binding cassette (ABC) transporters and the encoded protein contains two ATP-binding domains and 12 transmembrane regions. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies: ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White. This gene is a member of the MRP subfamily which is involved in multi-drug resistance. This gene and another subfamily member are arranged head-to-tail on chromosome 16q12.1. Increased expression of this gene is associated with breast cancer. [provided by RefSeq, Jul 2008]

Chromosome

16

Cytoband

q12.1

Chromosome location (bp)

48082973 - 48156018

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000140798 (version 78.38)

Entrez gene

94160

UniProt

Q96J65 (UniProt - Evidence at protein level)

neXtProt

NX_Q96J65

Antibodypedia

ABCC12 antibodies
 

PROTEIN VIEW

? »
 
 
 
ABCC12-001
 
ABCC12-010
 
 
 
 
 

PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ABCC12-001 ENSP00000311030
ENST00000311303
Q96J65
Show all »
Show » Show » 1359 152.3 No 9
ABCC12-010 ENSP00000436647
ENST00000527640
E9PHY2
Show all »
Show » 106 12 No 0