ADAM19

GENE INFORMATION

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Gene name

ADAM19 (HGNC Symbol)

Synonyms

MLTNB

Description

ADAM metallopeptidase domain 19 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This member is a type I transmembrane protein and serves as a marker for dendritic cell differentiation. It has been demonstrated to be an active metalloproteinase, which may be involved in normal physiological processes such as cell migration, cell adhesion, cell-cell and cell-matrix interactions, and signal transduction. It is proposed to play a role in pathological processes, such as cancer, inflammatory diseases, renal diseases, and Alzheimer's disease. [provided by RefSeq, May 2013]

Chromosome

5

Cytoband

q33.3

Chromosome location (bp)

157395534 - 157575775

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000135074 (version 78.38)

Entrez gene

8728

UniProt

Q9H013 (UniProt - Evidence at protein level)

neXtProt

NX_Q9H013

Antibodypedia

ADAM19 antibodies
 

PROTEIN VIEW

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ADAM19-001
 
ADAM19-003
 
ADAM19-004
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ADAM19-001 ENSP00000257527
ENST00000257527
Q9H013
Show all »
Show » Show » 918 100.8 Yes 1
ADAM19-003 ENSP00000428654
ENST00000517905
Q9H013
Show all »
Show » Show » 955 105 Yes 1
ADAM19-004 ENSP00000431027
ENST00000517374
Q8TBU7
Show all »
Show » Show » 489 52.7 No 1