NR1D1

GENE INFORMATION

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Gene name

NR1D1 (HGNC Symbol)

Synonyms

ear-1, hRev, Rev-ErbAalpha, THRA1, THRAL

Description

Nuclear receptor subfamily 1, group D, member 1 (HGNC Symbol)

Entrez gene summary

This gene encodes a transcription factor that is a member of the nuclear receptor subfamily 1. The encoded protein is a ligand-sensitive transcription factor that negatively regulates the expression of core clock proteins. In particular this protein represses the circadian clock transcription factor aryl hydrocarbon receptor nuclear translocator-like protein 1 (ARNTL). This protein may also be involved in regulating genes that function in metabolic, inflammatory and cardiovascular processes. [provided by RefSeq, Jan 2013]

Chromosome

17

Cytoband

q21.1

Chromosome location (bp)

40092787 - 40100725

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000126368 (version 78.38)

Entrez gene

9572

UniProt

P20393 (UniProt - Evidence at protein level)

neXtProt

NX_P20393

Antibodypedia

NR1D1 antibodies
 

PROTEIN VIEW

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NR1D1-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

NR1D1-001 ENSP00000246672
ENST00000246672
P20393
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