DDX31

GENERAL INFORMATION

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Gene name

DDX31

Gene description

DEAD (Asp-Glu-Ala-Asp) box polypeptide 31

Protein class

Enzymes
Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

5
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

Exocrine pancreas and renal tubules showed strong cytoplasmic positivity. A fraction of urothelial cells were moderately stained. The intestine displayed distinct luminal membranous staining. Remaining normal tissues were generally negative.

ANTIBODY RELIABILITY

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Data reliability
description

Pending RNA-based expert annotation.

Data reliability

Uncertain based on 1 antibody.
HPA020891
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Nasopharynx
N/A
N/A
Bronchus
N/A
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Pancreas

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Expressed in all

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

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Gene name

DDX31 (HGNC Symbol)

Synonyms

FLJ13633, FLJ14578, FLJ23349, PPP1R25

Description

DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 (HGNC Symbol)

Entrez gene summary

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a member of this family. The function of this member has not been determined. Alternative splicing of this gene generates 2 transcript variants. [provided by RefSeq, Jul 2008]

Chromosome

9

Cytoband

q34.13

Chromosome location (bp)

132592997 - 132670401

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000125485 (version 78.38)

Entrez gene

64794

UniProt

Q9H8H2 (UniProt - Evidence at protein level)

neXtProt

NX_Q9H8H2

Antibodypedia

DDX31 antibodies


PROTEIN BROWSER

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ENST00000310532
 
ENST00000372153
 
ENST00000372159
 
ENST00000438527
 
ENST00000480876
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

DDX31-001 ENSP00000361232
ENST00000372159
Q9H8H2
Show all »
Show » Show » 851 94.1 No 0
DDX31-003 ENSP00000310539
ENST00000310532
Q9H8H2
Show all »
Show » Show » 585 64.1 No 0
DDX31-004 ENSP00000479697
ENST00000480876
Q9H8H2
Show all »
Show » Show » 319 34.6 No 0
DDX31-006 ENSP00000387730
ENST00000438527
Show » Show » 746 83.5 No 0
DDX31-201 ENSP00000361226
ENST00000372153
Q9H8H2
Show all »
Show » Show » 851 94.1 No 0