SMAD9

GENERAL INFORMATION

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Gene name

SMAD9

Gene description

SMAD family member 9

Protein class

Disease related genes
Predicted intracellular proteins
Transcription factors

Predicted localization

Intracellular

Number of transcripts

3
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Tissue enhanced (thyroid gland)
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

Cytoplasmic and nuclear expression in several tissues.

ANTIBODY RELIABILITY

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Data reliability
description

Antibody staining mainly not consistent with RNA expression data.

Data reliability

Uncertain based on 2 antibodies.
HPA031162 , CAB009119
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Heart muscle

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Tissue enhanced (thyroid gland)

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

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Gene name

SMAD9 (HGNC Symbol)

Synonyms

MADH6, MADH9

Description

SMAD family member 9 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a member of the SMAD family, which transduces signals from TGF-beta family members. The encoded protein is activated by bone morphogenetic proteins and interacts with SMAD4. Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jan 2010]

Chromosome

13

Cytoband

q13.3

Chromosome location (bp)

36844831 - 36920765

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000120693 (version 78.38)

Entrez gene

4093

UniProt

O15198 (UniProt - Evidence at protein level)

neXtProt

NX_O15198

Antibodypedia

SMAD9 antibodies


PROTEIN BROWSER

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ENST00000350148
 
ENST00000379826
 
ENST00000399275
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SMAD9-001 ENSP00000239885
ENST00000350148
O15198
Show all »
Show » Show » 430 48.6 No 0
SMAD9-002 ENSP00000382216
ENST00000399275
O15198
Show all »
Show » Show » 467 52.5 No 0
SMAD9-201 ENSP00000369154
ENST00000379826
O15198
Show all »
Show » Show » 467 52.5 No 0