NEK2

GENE INFORMATION

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Gene name

NEK2 (HGNC Symbol)

Synonyms

NEK2A, NLK1, PPP1R111, RP67

Description

NIMA-related kinase 2 (HGNC Symbol)

Entrez gene summary

This gene encodes a serine/threonine-protein kinase that is involved in mitotic regulation. This protein is localized to the centrosome, and undetectable during G1 phase, but accumulates progressively throughout the S phase, reaching maximal levels in late G2 phase. Alternatively spliced transcript variants encoding different isoforms with distinct C-termini have been noted for this gene. [provided by RefSeq, Feb 2011]

Chromosome

1

Cytoband

q32.3

Chromosome location (bp)

211658657 - 211675630

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000117650 (version 78.38)

Entrez gene

4751

UniProt

P51955 (UniProt - Evidence at protein level)

neXtProt

NX_P51955

Antibodypedia

NEK2 antibodies
 

PROTEIN VIEW

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NEK2-001
 
NEK2-002
 
NEK2-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

NEK2-001 ENSP00000355966
ENST00000366999
P51955
Show all »
Show » Show » 445 51.8 No 0
NEK2-002 ENSP00000355965
ENST00000366998
P51955
Show all »
Show » Show » 384 44.9 No 0
NEK2-201 ENSP00000440237
ENST00000540251
Show » Show » 388 45.2 No 0