DARS

GENE INFORMATION

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Gene name

DARS

Synonyms

Description

Aspartyl-tRNA synthetase (HGNC Symbol)

Entrez gene summary

This gene encodes a member of a multienzyme complex that functions in mediating the attachment of amino acids to their cognate tRNAs. The encoded protein ligates L-aspartate to tRNA(Asp). Mutations in this gene have been found in patients showing hypomyelination with brainstem and spinal cord involvement and leg spasticity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014]

Chromosome

2

Cytoband

q21.3

Chromosome location (bp)

135906677 - 135986100

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000115866 (version 78.38)

Entrez gene

1615

UniProt

P14868 (UniProt - Evidence at protein level)

neXtProt

NX_P14868

Antibodypedia

DARS antibodies
 

PROTEIN VIEW

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DARS-001
 
DARS-002
 
DARS-003
 
DARS-004
 
DARS-009
 
DARS-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

DARS-001 ENSP00000264161
ENST00000264161
P14868
Show all »
Show » Show » 501 57.1 No 0
DARS-002 ENSP00000397616
ENST00000456565
C9J7S3
Show all »
Show » Show » 176 20 No 0
DARS-003 ENSP00000388801
ENST00000449218
C9JQM9
Show all »
Show » Show » 135 15.3 No 0
DARS-004 ENSP00000389867
ENST00000441323
C9JLC1
Show all »
Show » Show » 182 20.6 No 0
DARS-009 ENSP00000387508
ENST00000422708
H7BZ35
Show all »
Show » Show » 188 21.6 No 0
DARS-201 ENSP00000444192
ENST00000537273
P14868
Show all »
Show » Show » 401 45.8 No 0