GATA3

GENERAL INFORMATION

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Gene name

GATA3

Gene description

GATA binding protein 3

Protein class

Cancer-related genes
Disease related genes
Plasma proteins
Predicted intracellular proteins
Transcription factors

Predicted localization

Intracellular

Number of transcripts

2
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Tissue enhanced (skin)
GTEx:Group enriched (breast, skin, urinary bladder)

Protein evidence

Evidence at protein level

Protein localization

Nuclear expression mainly in breast, skin and urinary bladder.

ANTIBODY RELIABILITY

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Data reliability
description

Pending RNA-based expert annotation.

Data reliability

Supportive based on 3 antibodies.
HPA029730 , HPA029731 , CAB016217
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

Breast



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Tissue enhanced (skin)

Organ

Expression

GTEx dataset
RNA tissue category:  Group enriched (breast, skin, urinary bladder)

Organ

Expression



GENE INFORMATION

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Gene name

GATA3 (HGNC Symbol)

Synonyms

HDR

Description

GATA binding protein 3 (HGNC Symbol)

Entrez gene summary

This gene encodes a protein which belongs to the GATA family of transcription factors. The protein contains two GATA-type zinc fingers and is an important regulator of T-cell development and plays an important role in endothelial cell biology. Defects in this gene are the cause of hypoparathyroidism with sensorineural deafness and renal dysplasia. [provided by RefSeq, Nov 2009]

Chromosome

10

Cytoband

p14

Chromosome location (bp)

8053604 - 8075198

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000107485 (version 78.38)

Entrez gene

2625

UniProt

P23771 (UniProt - Evidence at protein level)

neXtProt

NX_P23771

Antibodypedia

GATA3 antibodies


PROTEIN BROWSER

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ENST00000346208
 
ENST00000379328
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

GATA3-001 ENSP00000368632
ENST00000379328
P23771
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Show » Show » 444 48 No 0
GATA3-002 ENSP00000341619
ENST00000346208
P23771
Show all »
Show » Show » 443 47.9 No 0