KCNN4

GENE INFORMATION

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Gene name

KCNN4 (HGNC Symbol)

Synonyms

hIKCa1, hKCa4, hSK4, KCa3.1

Description

Potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is part of a potentially heterotetrameric voltage-independent potassium channel that is activated by intracellular calcium. Activation is followed by membrane hyperpolarization, which promotes calcium influx. The encoded protein may be part of the predominant calcium-activated potassium channel in T-lymphocytes. This gene is similar to other KCNN family potassium channel genes, but it differs enough to possibly be considered as part of a new subfamily. [provided by RefSeq, Jul 2008]

Chromosome

19

Cytoband

q13.31

Chromosome location (bp)

43766533 - 43781257

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000104783 (version 78.38)

Entrez gene

3783

UniProt

O15554 (UniProt - Evidence at protein level)

neXtProt

NX_O15554

Antibodypedia

KCNN4 antibodies
 

PROTEIN VIEW

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KCNN4-001
 
KCNN4-010
 
KCNN4-013
 
KCNN4-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

KCNN4-001 ENSP00000262888
ENST00000262888
O15554
Show all »
Show » Show » 427 47.7 No 6
KCNN4-010 ENSP00000471900
ENST00000598836
M0QZ70
Show all »
Show » Show » 165 18.4 Yes 0
KCNN4-013 ENSP00000470339
ENST00000600909
M0QZ70
Show all »
Show » Show » 59 6.6 No 0
KCNN4-201 ENSP00000485014
ENST00000615047
D1MQ08
Show all »
Show » Show » 295 33.4 No 3