GATA1

GENERAL INFORMATION

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Gene name

GATA1

Gene description

GATA binding protein 1 (globin transcription factor 1)

Protein class

Cancer-related genes
Disease related genes
Predicted intracellular proteins
Transcription factors

Predicted localization

Intracellular

Number of transcripts

2
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Tissue enriched (bone marrow)
GTEx:Tissue enhanced (lung, spleen, testis)

Protein evidence

Evidence at protein level

Protein localization

Selective nuclear expression in hematopoietic cells.

ANTIBODY RELIABILITY

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Data reliability
description

Antibody staining mainly consistent with RNA expression data.

Data reliability

Supportive based on 3 antibodies.
HPA000232 , HPA000233 , CAB009195
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Bone marrow

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Tissue enriched (bone marrow)

Organ

Expression

GTEx dataset
RNA tissue category:  Tissue enhanced (lung, spleen, testis)

Organ

Expression



GENE INFORMATION

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Gene name

GATA1 (HGNC Symbol)

Synonyms

ERYF1, GATA-1, GF1, NF-E1, NFE1

Description

GATA binding protein 1 (globin transcription factor 1) (HGNC Symbol)

Entrez gene summary

This gene encodes a protein which belongs to the GATA family of transcription factors. The protein plays an important role in erythroid development by regulating the switch of fetal hemoglobin to adult hemoglobin. Mutations in this gene have been associated with X-linked dyserythropoietic anemia and thrombocytopenia. [provided by RefSeq, Jul 2008]

Chromosome

X

Cytoband

p11.23

Chromosome location (bp)

48786554 - 48794311

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000102145 (version 78.38)

Entrez gene

2623

UniProt

P15976 (UniProt - Evidence at protein level)

neXtProt

NX_P15976

Antibodypedia

GATA1 antibodies


PROTEIN BROWSER

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ENST00000376665
 
ENST00000376670
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

GATA1-001 ENSP00000365858
ENST00000376670
P15976
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Show » Show » 413 42.8 No 0
GATA1-002 ENSP00000365853
ENST00000376665
B7WNQ9
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Show » Show » 334 35.3 No 0