CHGA

GENE INFORMATION

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Gene name

CHGA

Synonyms

Description

Chromogranin A (parathyroid secretory protein 1) (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. It is found in secretory vesicles of neurons and endocrine cells. This gene product is a precursor to three biologically active peptides; vasostatin, pancreastatin, and parastatin. These peptides act as autocrine or paracrine negative modulators of the neuroendocrine system. Two other peptides, catestatin and chromofungin, have antimicrobial activity and antifungal activity, respectively. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2014]

Chromosome

14

Cytoband

q32.12

Chromosome location (bp)

92923080 - 92935293

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000100604 (version 78.38)

Entrez gene

1113

UniProt

P10645 (UniProt - Evidence at protein level)

neXtProt

NX_P10645

Antibodypedia

CHGA antibodies
 

PROTEIN VIEW

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CHGA-001
 
CHGA-003
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CHGA-001 ENSP00000216492
ENST00000216492
P10645
Show all »
Show » Show » 457 50.7 Yes 0
CHGA-003 ENSP00000334023
ENST00000334654
G5E968
Show all »
Show » Show » 306 34.3 Yes 0