ADRBK2

GENE INFORMATION

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Gene name

ADRBK2 (HGNC Symbol)

Synonyms

BARK2, GRK3

Description

Adrenergic, beta, receptor kinase 2 (HGNC Symbol)

Entrez gene summary

The beta-adrenergic receptor kinase specifically phosphorylates the agonist-occupied form of the beta-adrenergic and related G protein-coupled receptors. Overall, the beta adrenergic receptor kinase 2 has 85% amino acid similarity with beta adrenergic receptor kinase 1, with the protein kinase catalytic domain having 95% similarity. These data suggest the existence of a family of receptor kinases which may serve broadly to regulate receptor function. [provided by RefSeq, Jul 2008]

Chromosome

22

Cytoband

q12.1

Chromosome location (bp)

25564849 - 25729294

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000100077 (version 78.38)

Entrez gene

157

UniProt

P35626 (UniProt - Evidence at protein level)

neXtProt

NX_P35626

Antibodypedia

ADRBK2 antibodies
 

PROTEIN VIEW

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ADRBK2-001
 
ADRBK2-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ADRBK2-001 ENSP00000317578
ENST00000324198
P35626
Show all »
Show » Show » 688 79.7 No 0
ADRBK2-201 ENSP00000478925
ENST00000619906
Q8N433
Show all »
Show » Show » 387 44.6 No 0