ABCC6

GENE INFORMATION

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Gene name

ABCC6 (HGNC Symbol)

Synonyms

ARA, EST349056, MLP1, MRP6, PXE, URG7

Description

ATP-binding cassette, sub-family C (CFTR/MRP), member 6 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). The encoded protein, a member of the MRP subfamily, is involved in multi-drug resistance. Mutations in this gene cause pseudoxanthoma elasticum. Alternatively spliced transcript variants that encode different proteins have been described for this gene. [provided by RefSeq, Jul 2008]

Chromosome

16

Cytoband

p13.11

Chromosome location (bp)

16148928 - 16223522

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000091262 (version 78.38)

Entrez gene

368

UniProt

O95255 (UniProt - Evidence at protein level)

neXtProt

NX_O95255

Antibodypedia

ABCC6 antibodies
 

PROTEIN VIEW

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ABCC6-001
 
ABCC6-006
 
ABCC6-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ABCC6-001 ENSP00000205557
ENST00000205557
O95255
Show all »
Show » Show » 1503 164.9 No >9
ABCC6-006 ENSP00000461686
ENST00000575728
O95255
Show all »
Show » Show » 99 10.8 No 1
ABCC6-201 ENSP00000483331
ENST00000622290
E7ESW8
Show all »
Show » Show » 871 95.9 No >9