ADAM11

GENE INFORMATION

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Gene name

ADAM11 (HGNC Symbol)

Synonyms

MDC

Description

ADAM metallopeptidase domain 11 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the ADAM (a disintegrin and metalloprotease) protein family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This gene represents a candidate tumor suppressor gene for human breast cancer based on its location within a minimal region of chromosome 17q21 previously defined by tumor deletion mapping. [provided by RefSeq, Dec 2014]

Chromosome

17

Cytoband

q21.31

Chromosome location (bp)

44759031 - 44781846

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000073670 (version 78.38)

Entrez gene

4185

UniProt

O75078 (UniProt - Evidence at transcript level)

neXtProt

NX_O75078

Antibodypedia

ADAM11 antibodies
 

PROTEIN VIEW

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ADAM11-001
 
ADAM11-004
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ADAM11-001 ENSP00000200557
ENST00000200557
O75078
Show all »
Show » Show » 769 83.4 Yes 1
ADAM11-004 ENSP00000443773
ENST00000535346
B4DKD2
Show all »
Show » Show » 569 61.6 No 1