NGFR

GENERAL INFORMATION

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Gene name

NGFR

Gene description

Nerve growth factor receptor

Protein class

Cancer-related genes
CD markers
Predicted intracellular proteins
Predicted membrane proteins
RAS pathway related proteins

Predicted localization

Intracellular,Membrane

Number of transcripts

3
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Mixed
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

Selective cytoplasmic expression in peripheral nerves, reticular fibers of germinal centra, myoepthelia and basal cells of surface epithelium and glandular epithelia of seminal vesicle and prostate.

ANTIBODY RELIABILITY

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Data reliability
description

Pending RNA-based expert annotation.

Data reliability

Supportive based on 3 antibodies.
HPA004765 , CAB000143 , CAB001995
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Small intestine

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Mixed

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

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Gene name

NGFR (HGNC Symbol)

Synonyms

CD271, p75NTR, TNFRSF16

Description

Nerve growth factor receptor (HGNC Symbol)

Entrez gene summary

Nerve growth factor receptor contains an extracellular domain containing four 40-amino acid repeats with 6 cysteine residues at conserved positions followed by a serine/threonine-rich region, a single transmembrane domain, and a 155-amino acid cytoplasmic domain. The cysteine-rich region contains the nerve growth factor binding domain. [provided by RefSeq, Jul 2008]

Chromosome

17

Cytoband

q21.33

Chromosome location (bp)

49495293 - 49515017

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000064300 (version 78.38)

Entrez gene

4804

UniProt

P08138 (UniProt - Evidence at protein level)

neXtProt

NX_P08138

Antibodypedia

NGFR antibodies


PROTEIN BROWSER

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ENST00000172229
 
ENST00000504201
 
ENST00000509200
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

NGFR-001 ENSP00000172229
ENST00000172229
P08138
Show all »
Show » Show » 427 45.2 Yes 1
NGFR-002 ENSP00000421731
ENST00000504201
B4E096
Show all »
Show » Show » 333 35.8 No 1
NGFR-003 ENSP00000421514
ENST00000509200
Show » 4 0.4 No 0