FYN

GENERAL INFORMATION

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Gene name

FYN

Gene description

FYN proto-oncogene, Src family tyrosine kinase

Protein class

Enzymes
Plasma proteins
Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

19
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

Cytoplasmic expression mainly in in lymphoid tissues and in neuropil.

ANTIBODY RELIABILITY

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Data reliability
description

Pending RNA-based expert annotation.

Data reliability

Supportive based on 3 antibodies.
HPA023887 , CAB005034 , CAB018387
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Expressed in all

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

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Gene name

FYN (HGNC Symbol)

Synonyms

MGC45350, SLK, SYN

Description

FYN proto-oncogene, Src family tyrosine kinase (HGNC Symbol)

Entrez gene summary

This gene is a member of the protein-tyrosine kinase oncogene family. It encodes a membrane-associated tyrosine kinase that has been implicated in the control of cell growth. The protein associates with the p85 subunit of phosphatidylinositol 3-kinase and interacts with the fyn-binding protein. Alternatively spliced transcript variants encoding distinct isoforms exist. [provided by RefSeq, Jul 2008]

Chromosome

6

Cytoband

q21

Chromosome location (bp)

111660332 - 111873452

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000010810 (version 78.38)

Entrez gene

2534

UniProt

P06241 (UniProt - Evidence at protein level)

neXtProt

NX_P06241

Antibodypedia

FYN antibodies


PROTEIN BROWSER

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 « 
 
ENST00000229471
 
ENST00000354650
 
ENST00000368667
 
ENST00000368678
 
ENST00000368682
 
ENST00000462598
 
ENST00000462856
 
ENST00000484067
 
ENST00000487824
 
ENST00000517419
 
ENST00000518295
 
ENST00000518630
 
ENST00000520518
 
ENST00000521062
 
ENST00000523238
 
ENST00000523570
 
ENST00000523574
 
ENST00000524310
 
ENST00000538466
 
 » 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

FYN-001 ENSP00000346671
ENST00000354650
P06241
Show all »
Show » Show » 537 60.8 No 0
FYN-002 ENSP00000357671
ENST00000368682
P06241
Show all »
Show » Show » 534 60.1 No 0
FYN-010 ENSP00000429590
ENST00000462598
E5RHX7
Show all »
Show » 70 7.5 No 0
FYN-011 ENSP00000427993
ENST00000462856
E5RFS5
Show all »
Show » Show » 232 26 No 0
FYN-012 ENSP00000430364
ENST00000523238
E5RFM0
Show all »
Show » Show » 152 16.7 No 0
FYN-013 ENSP00000428042
ENST00000521062
E5RFM6
Show all »
Show » Show » 103 11.1 No 0
FYN-014 ENSP00000357656
ENST00000368667
P06241
Show all »
Show » Show » 537 60.8 No 0
FYN-017 ENSP00000357667
ENST00000368678
P06241
Show all »
Show » Show » 534 60.1 No 0
FYN-018 ENSP00000428983
ENST00000484067
E5RK23
Show all »
Show » Show » 106 11.4 No 0
FYN-019 ENSP00000429813
ENST00000518630
E5RHF7
Show all »
Show » Show » 118 12.8 No 0
FYN-020 ENSP00000429294
ENST00000520518
E5RIX5
Show all »
Show » Show » 186 20.5 No 0
FYN-022 ENSP00000428695
ENST00000518295
E5RGT0
Show all »
Show » Show » 153 16.8 No 0
FYN-023 ENSP00000428045
ENST00000523570
E5RFM4
Show all »
Show » Show » 116 12.6 No 0
FYN-024 ENSP00000430455
ENST00000487824
E5RJX7
Show all »
Show » 65 7 No 0
FYN-025 ENSP00000429992
ENST00000523574
E5RGM6
Show all »
Show » Show » 140 15.3 No 0
FYN-026 ENSP00000428493
ENST00000524310
E5RI25
Show all »
Show » Show » 145 15.8 No 0
FYN-028 ENSP00000429866
ENST00000517419
E5RH71
Show all »
Show » Show » 175 19.3 No 0
FYN-029 ENSP00000229471
ENST00000229471
P06241
Show all »
Show » Show » 482 54.5 No 0
FYN-201 ENSP00000440646
ENST00000538466
P06241
Show all »
Show » Show » 534 60.1 No 0